Inzicht in de relaties tussen MRD en CAR T-celtherapie
What is MRD in cancer treatment? Measurable Residual Disease, or MRD, is the name for the very few cancer cells that stay in the body after or during treatment. Flow cytometry, polymerase chain reaction (PCR), or next-generati..
Mesenchymale stamceltherapie bij neurologische aandoeningen
Neurological diseases are big problems around the world because they cause a lot of death and disability. Traditional treatments haven't always worked, which has led to a change toward new methods like cell-based therapies. Beca..
De FDA heeft de aanwijzing als weesgeneesmiddel gegeven aan CART T-Cell Therapy A2B530 voor de behandeling van colorectale kanker
In March 2024, a news release said that A2B530 (A2 Biotherapeutics), a CAR T-cell therapy, had been given Orphan Drug Designation to treat colorectal cancer that expresses carcinoembryonic antigen (CEA) and has lost HLA-A*02 expr..
Iovance's Amtagvi is door USFDA goedgekeurd als eerste T-celtherapie voor een solide tumor
Iovance Biotherapeutics' first-of-its-kind immunotherapy was approved by the FDA. This means that T-cell therapy, which has changed the way some types of blood cancer are treated, can now be used directly on solid tumors.The drug..
Amivantamab-vmjw is goedgekeurd door de USFDA voor EGFR exon 20 insertie-gemuteerde niet-kleincellige longkanker-indicaties
The Food and Drug Administration approved amivantamab-vmjw (Rybrevant, Janssen Biotech, Inc.) in combination with carboplatin and pemetrexed on March 1, 2024. Patients with epidermal growth factor receptor (EGFR) exon 20 insertio..
Osimertinib met chemotherapie is door de USFDA goedgekeurd voor EGFR-gemuteerde niet-kleincellige longkanker
The Food and Drug Administration approved osimertinib (Tagrisso, AstraZeneca Pharmaceuticals LP) in combination with platinum-based chemotherapy for patients with locally advanced or metastatic non-small cell lung cancer (la/mNSC..
Lifileucel is door de USFDA goedgekeurd voor inoperabel of gemetastaseerd melanoom
The Food and Drug Administration granted accelerated approval to lifileucel (Amtagvi, Iovance Biotherapeutics, Inc.) on February 16, 2024. This approval is for adult patients with unresectable or metastatic melanoma who have been..
Tepotinib is door de USFDA goedgekeurd voor gemetastaseerde niet-kleincellige longkanker
The Food and Drug Administration officially approved tepotinib (Tepmetko, EMD Serono, Inc.) on February 15, 2024, for adult patients with metastatic non-small cell lung cancer (NSCLC) that had mesenchymal-epithelial transition (M..
Irinotecan-liposoom is door de USFDA goedgekeurd voor eerstelijnsbehandeling van gemetastaseerd adenocarcinoom van de pancreas
The Food and Drug Administration approved irinotecan liposome (Onivyde, Ipsen Biopharmaceuticals, Inc.) with oxaliplatin, fluorouracil, and leucovorin on February 13, 2024, for treating metastatic pancreatic adenocarcinoma as the..
Erdafitinib is goedgekeurd door USFDA voor lokaal gevorderd of gemetastaseerd urotheelcarcinoom
Erdafitinib (Balversa, Janssen Biotech) was approved by the Food and Drug Administration on January 19, 2024, for adult patients with FGFR3 genetic changes who have locally advanced or metastatic urothelial carcinoma (mUC). Patie..