Verstaan verhoudings tussen MRD en CAR T-Sel terapie
What is MRD in cancer treatment? Measurable Residual Disease, or MRD, is the name for the very few cancer cells that stay in the body after or during treatment. Flow cytometry, polymerase chain reaction (PCR), or next-generati..
Mesenchimale stamselterapie in neurologiese afwykings
Neurological diseases are big problems around the world because they cause a lot of death and disability. Traditional treatments haven't always worked, which has led to a change toward new methods like cell-based therapies. Beca..
Weesgeneesmiddelbenaming word deur FDA aan CART T-Cell Therapy A2B530 gegee vir die behandeling van kolorektale kanker
In March 2024, a news release said that A2B530 (A2 Biotherapeutics), a CAR T-cell therapy, had been given Orphan Drug Designation to treat colorectal cancer that expresses carcinoembryonic antigen (CEA) and has lost HLA-A*02 expr..
Iovance se Amtagvi word deur die USFDA goedgekeur as eerste T-selterapie vir 'n soliede gewas
Iovance Biotherapeutics' first-of-its-kind immunotherapy was approved by the FDA. This means that T-cell therapy, which has changed the way some types of blood cancer are treated, can now be used directly on solid tumors.The drug..
Amivantamab-vmjw is deur die USFDA goedgekeur vir EGFR ekson 20 invoeging-gemuteerde nie-kleinselle longkanker indikasies
The Food and Drug Administration approved amivantamab-vmjw (Rybrevant, Janssen Biotech, Inc.) in combination with carboplatin and pemetrexed on March 1, 2024. Patients with epidermal growth factor receptor (EGFR) exon 20 insertio..
Osimertinib met chemoterapie word deur die USFDA goedgekeur vir EGFR-gemuteerde nie-kleinselle longkanker
The Food and Drug Administration approved osimertinib (Tagrisso, AstraZeneca Pharmaceuticals LP) in combination with platinum-based chemotherapy for patients with locally advanced or metastatic non-small cell lung cancer (la/mNSC..
Lifileucel word deur die USFDA goedgekeur vir nie-opereerbare of metastatiese melanoom
The Food and Drug Administration granted accelerated approval to lifileucel (Amtagvi, Iovance Biotherapeutics, Inc.) on February 16, 2024. This approval is for adult patients with unresectable or metastatic melanoma who have been..
Tepotinib word deur die USFDA goedgekeur vir metastatiese nie-kleinselle longkanker
The Food and Drug Administration officially approved tepotinib (Tepmetko, EMD Serono, Inc.) on February 15, 2024, for adult patients with metastatic non-small cell lung cancer (NSCLC) that had mesenchymal-epithelial transition (M..
Irinotecan liposoom is goedgekeur deur die USFDA vir eerste-lyn behandeling van metastatiese pankreas adenokarsinoom
The Food and Drug Administration approved irinotecan liposome (Onivyde, Ipsen Biopharmaceuticals, Inc.) with oxaliplatin, fluorouracil, and leucovorin on February 13, 2024, for treating metastatic pancreatic adenocarcinoma as the..
Erdafitinib is deur die USFDA goedgekeur vir plaaslik gevorderde of metastatiese urotheelkarsinoom
Erdafitinib (Balversa, Janssen Biotech) was approved by the Food and Drug Administration on January 19, 2024, for adult patients with FGFR3 genetic changes who have locally advanced or metastatic urothelial carcinoma (mUC). Patie..