Izixazululo Ezithuthukisiwe Zokwelapha Umdlavuza
"Sixhuma iziguli ezinomdlavuza ezisezingeni eliphezulu ukuze ziphumelele ekwelashweni kwamaseli kanye nokuhlolwa komtholampilo."
Sisebenza phezulu
izibhedlela zomdlavuza emhlabeni
"Izixazululo ezithuthukisiwe zokwelapha umdlavuza ezinomkhawulo
Ukwelashwa kwe-CAR T-Cell, ukwelashwa kwe-TIL, nezivivinyo zomtholampilo.
Hlanganyela nathi ekulweni nomdlavuza namuhla!"
“Ngezixazululo ezintsha nokuzinikela okungantengantengi, silwela ukuqeda izithiyo, sinikeze ithemba, futhi
nomthelela ezweni lapho umdlavuza ungelapheki nje kuphela kodwa unganqotshwa.”
I-CAR T-cell Therapy, Izilingo Zomtholampilo
Nokwelashwa Kwamanye Amazwe
1.
Ukwelashwa Kwamaseli
ICancerFax iyinkundla yokuphayona ezinikele ekuxhumaniseni abantu ababhekene nomdlavuza osezingeni eliphezulu ngemithi yokwelapha yamangqamuzana eyisisekelo njengokwelashwa kwe-CAR T-Cell, ukwelashwa kwe-TIL, nezivivinyo zomtholampilo emhlabeni wonke. Le sevisi esindisa ukuphila inika iziguli amandla okuhlola imingcele emisha ekwelapheni umdlavuza kuyilapho izinikeza ulwazi oluphelele mayelana nemibandela yokufaneleka yokuhlolwa, izindawo, nezinqubo zokubhalisa.
2.
Ukwelashwa Kwamanye Amazwe
ICancerFax ingumsizi wesiguli othenjwa kakhulu emhlabeni wonke, esebenza nezibhedlela eziphezulu zomdlavuza emhlabeni wonke njengo-MD Anderson, Dana Farber, Mayo Clinic, Parkway Singapore, Asan, Sheba, NCC Japan, Beijing Cancer Institute, Apollo, kanye neBLK Max ukukulethela izidakamizwa zakamuva kanye nokwelapha. Ithimba lethu liqinisekisa ukuthi iziguli zithola izinsiza ze-concierge ukuze zelashwe umdlavuza e-USA, Japan, South Korea, Israel, China, nase-India.
3.
Izivivinyo zemitholampilo
Inkampani yethu igxile kakhulu ezinsizeni zokuhlolwa komdlavuza, yenza kube lula ukufinyelela ocwaningweni oluyisisekelo kanye nezinketho zokwelapha. Sixhuma iziguli nezivivinyo ezisezingeni eliphezulu, ezikhuthaza ithemba kanye nenqubekelaphambili ekulweni nomdlavuza. Ngokuzibophezela ekwenzeni ngcono izimpilo, sihamba phambili ekuthuthukiseni ukunakekelwa komdlavuza ngokusungula izindlela ezintsha zomtholampilo.
- Izivivinyo zemitholampilo
- I-CAR T-Cell Therapy
- Ukwelashwa komdlavuza e-USA
- Ukwelapha umdlavuza eNdiya
- Ukwelashwa komdlavuza eSingapore
- Ukwelashwa komdlavuza eSouth-Korea
- Ukwelashwa komdlavuza kwa-Israyeli
- Ukwelashwa kwe-CAR T-Cell eNdiya
- Ukwelashwa kwe-CAR T-Cell eChina
- Ukwelashwa kwe-CAR T-Cell kwa-Israyeli
- I-CAR T-Cell therapy eSingapore
- ICancerFax: Ukunika Izimpilo Amandla, Ukuguqula Uhambo
Izivivinyo zemitholampilo
ICancerFax igxile kakhulu ekuqondiseni abantu ngenqubo eyinkimbinkimbi yokubhalisa ezivivinyweni zomtholampilo zomdlavuza. Ngokuzinikezela okungantengantengi, sixhuma iziguli ocwaningweni olusezingeni eliphezulu kanye nezinketho zokwelapha, sinikeza umzila wethemba empini yazo yokulwa nomdlavuza. Ithimba lethu lochwepheshe abanozwela lizulazula emhlabeni oyinkimbinkimbi wezivivinyo zomtholampilo, liqinisekisa ukuthi sonke isiguli sithola ukwesekwa komuntu siqu kanye nesiqondiso. Sizibophezele ekunikezeni amandla iziguli, ukuzinikeza ukufinyelela ekwelapheni okusha, kanye nokuqhubekisela phambili impi yokulwa nomdlavuza. Enkampanini yethu, sikholwa ukuthi ukuhlanganyela ezivivinyweni zomtholampilo kungaba isinyathelo esibalulekile esiya ekusasa eliqhakazile.
Hlola imininingwane
I-CAR T-Cell Therapy
Ukwelashwa kwe-CAR T Cell kuyindlela yokuguqula i-immunotherapy enikeza ithemba elisha ekulweni nomdlavuza. I-CAR, emele i-Chimeric Antigen Receptor, iyisamukeli sokwenziwa esakhelwe ama-T cell esiguli, isivikelo esingokwemvelo somzimba ezifweni. Lawa maseli e-CAR T ashintshiwe aklanyelwe ukubona futhi ahlasele amangqamuzana omdlavuza athile ngokunemba, konga izicubu ezinempilo. Ukwelashwa kwe-CAR T cell kubonise impumelelo ephawulekayo, ikakhulukazi ekwelapheni izinhlobo ezithile ze-leukemia ne-lymphoma, okuholela ekukhululweni nasekuthuthukisweni kwamazinga okusinda kwezinye izimo. Naphezu kwezinselele ezifana nemiphumela engemihle engase ibe khona kanye nezindleko eziphakeme, ucwaningo oluqhubekayo luhlose ukwandisa ukusetshenziswa kwalo ezinhlobonhlobo zomdlavuza, okuthembisa ikusasa eliqhakazile empini yokulwa nalesi sifo esesabekayo.
Hlola imininingwane
Ukwelashwa komdlavuza e-USA
E-USA, ukunakekelwa komdlavuza osezingeni eliphezulu kuwukuhlanganiswa okumangalisayo kokuqanjwa kabusha, ucwaningo, nokunakekelwa okuhlanganisa konke. Izibhedlela eziphezulu zomdlavuza e-USA sebenzisa ubuchwepheshe obusezingeni eliphezulu njenge-immunotherapy kanye nemithi enembile ukwenza izindlela zokwelapha ngokwezifiso zofuzo lwesiguli ngasinye kanye nohlobo lomdlavuza. Leli su elenzelwe wena likhiqize imiphumela engcono kanye nemiphumela engemihle embalwa. Izivivinyo zemitholampilo nazo zifinyeleleka kalula, okunikeza iziguli ukufinyelela ekwelashweni okusha okubonisa isithembiso sesikhathi esizayo. Kodwa-ke, izindleko eziphezulu zokwelashwa komdlavuza zisaqhubeka nokuba yinkinga, okuqubula izingxoxo eziqhubekayo mayelana nokufinyelela kanye nokufinyeleleka kokunakekelwa kwezempilo. Iziguli ezinomdlavuza kanye nemindeni yazo zisaqhubeka nokuba nethemba ngenxa yokuzinikela kwe-USA ekwelapheni umdlavuza.
Hlola imininingwane
Ukwelapha umdlavuza eNdiya
Ukwelashwa komdlavuza e-India kwenze intuthuko enkulu, kuhlinzeka ngemithi yokwelapha ethuthukisiwe njengokuhlinzwa, i-chemotherapy, imisebe, kanye ne-immunotherapy. Izibhedlela eziphezulu zomdlavuza eNdiya njenge-Tata Memorial Centre, i-Apollo Cancer Hospital, i-BLK, i-Artemis, i-Asian Oncology, i-American Oncology, i-HCG, njll., inikeza ukunakekelwa okusezingeni lomhlaba. Inzuzo ye-India isekuthengeni, ukuheha abavakashi bezokwelapha abafuna ukwelashwa komdlavuza kwekhwalithi ephezulu, nengabizi.
Hlola imininingwane
Ukwelashwa komdlavuza eSingapore
Ukwelashwa komdlavuza eSingapore kubonakala ngobuchwepheshe bezokwelapha obusezingeni eliphezulu kanye nendlela ephelele yokunakekela. Izikhungo ezisezingeni lomhlaba njengeParkway Cancer Center zihlinzeka ngohlu olubanzi lwezindlela zokwelapha, kusukela ekuhlinzweni nasekwelapheni ngamakhemikhali kuya ekwelapheni okuhlosiwe kanye ne-immunotherapy. Amaqembu ahlukahlukene ongoti be-oncologists abanolwazi benza izinhlelo zokwelashwa eziqondene nomuntu, ziqinisekisa imiphumela engcono kakhulu yeziguli. Uhlelo lwezempilo lwaseSingapore lwaziwa ngokusebenza kahle kwalo nokufinyeleleka, luheha iziguli emhlabeni wonke. Ngaphandle kokunakekelwa kwezokwelapha, izwe linikeza indawo esekela iziguli nemindeni yazo, ngamaqembu amaningi okusekela kanye nezinsizakalo zokwelulekwa ukusiza ukuzulazula ohambweni oluyinselele lokwelashwa komdlavuza.
Hlola imininingwane
Ukwelashwa komdlavuza eSouth-Korea
Ukwelashwa komdlavuza eSouth Korea kubonakala ngenhlanganisela evumelanayo yezindlela zendabuko nesimanje ekunakekelweni kwezempilo. Izikhungo zezokwelapha ezihamba phambili njengeNational Cancer Center Korea kanye ne-Asan Medical Center zinikeza ubuchwepheshe besimanje kanye nendlela ephelele yokugxilisa isiguli. Uhlelo lokunakekelwa kwezempilo lwaseNingizimu Korea ludume ngokusebenza kahle kwalo, ukufinyeleleka, kanye nekhwalithi yokunakekelwa, luheha iziguli emhlabeni wonke. Izwe linomkhakha wezokuvakasha wezokwelapha ophumelelayo, ohlinzeka ngemithi ethuthukisiwe njengomuthi onembile kanye nokwelashwa kwamasosha omzimba. Iziguli azizuzi nje kuphela ekwelashweni kwesimanjemanje kodwa futhi kusukela ohlelweni olusekelayo lwe-ecosystem yocwaningo, izivivinyo zemitholampilo, kanye nezinsizakalo ezibanzi zokunakekelwa komdlavuza.
Hlola imininingwane
Ukwelashwa komdlavuza kwa-Israyeli
Ukwelashwa komdlavuza kwa-Israyeli kumi phambili emisha yezokwelapha. Idume ngocwaningo lwayo oluthuthukisiwe kanye nemithi yokuphayona, uhlelo lwezempilo lwakwa-Israel lunikeza ukunakekelwa kwe-oncology okusezingeni lomhlaba. Izikhungo ezihamba phambili ezifana neSheba Medical Center kanye neSibhedlela saseHadassah zisebenzisa ubuchwepheshe besimanjemanje, umuthi oqondile, kanye nokwelashwa kwamasosha omzimba ukuze kuliwe nomdlavuza ngempumelelo. Indawo yokusebenzisana yakwa-Israel ikhuthaza ucwaningo oluyisisekelo kanye nezivivinyo zomtholampilo, ikwenze kube isizinda sokuqanjwa kabusha kwe-oncology. Ukwengeza, indlela yozwela nemikhakha eminingi iqinisekisa ukunakekelwa kwesiguli okuphelele, kuyilapho abavakashi bezokwelapha befuna ubuchwepheshe bayo. Ukuzibophezela kuka-Israyeli ekwelashweni komdlavuza kudlulela ngale kwemingcele, kunikeza ithemba nezixazululo ezithuthukile ezigulini emhlabeni wonke.
Ukwelashwa kwe-CAR T-Cell eNdiya
I-CAR-T cell therapy yaseNdiya, i-NexCAR19, iyisu lokuqala lezwe lendabuko lokulwa nomdlavuza. Idalwe yi-ImmunoACT, igatsha le-IIT Bombay, lokhu kwelashwa okuthuthukisiwe kusebenzisa ama-T-cell ashintshwe izakhi ukuze aqondise futhi aqede amangqamuzana anomdlavuza, ikakhulukazi emazingeni egazi afana ne-leukemia kanye ne-lymphomas. Izivivinyo zokuqala zibonisa amandla, cishe amaphesenti angama-50 athola ukuxolelwa okuphelele, ikakhulukazi ezimweni zentsha ze-B-cell acute lymphoblastic leukemia. I-NexCAR19 ibonisa ukuncipha kwe-neurotoxicity uma kuqhathaniswa nezinketho zangaphandle, okubonisa izinzuzo ezingaba khona phezu kokwelashwa kwamanje. I-India ihlela ukunikeza lokhu kwelashwa ngezindleko ezincishisiwe uma kuqhathaniswa nezintengo zomhlaba wonke, kusukela ku-INR 30–40 lakhs futhi ihlose ukuyehlisa ibe ngama-INR 10–20 lakhs ngemvume engokomthetho.
Hlola imininingwane
Ukwelashwa kwe-CAR T-Cell eChina
Ukwelashwa kwe-CAR T-cell eChina ibone intuthuko emangalisayo eminyakeni yamuva nje, ikhombisa inqubekelaphambili yomhlaba wonke kulokhu kwelashwa komdlavuza osezingeni eliphezulu. Njengoba kunezilingo zomtholampilo eziqhubekayo ezingaphezu kuka-700, i-China ihola ukuthuthukiswa kokwelashwa kwe-CAR T-Cell. I-China iye yakwamukela ngokushesha ukwelashwa kwe-CAR T-cell, okunikeza ithemba elisha ezigulini ezilwa nomdlavuza ohlukahlukene, okuhlanganisa i-leukemia ne-lymphoma. Izibhedlela eziningana zaseShayina nezikhungo zocwaningo ziqhuba izivivinyo zemitholampilo ngenkuthalo futhi zihlinzeka ngokwelashwa kwe-CAR T-cell ezigulini ezifanele. Ingqalasizinda eqinile yezwe kanye nokufinyelela kubantu abaningi abaneziguli kusheshise imizamo yocwaningo nentuthuko. Ngokuzibophezela ekuthuthukiseni lolu hlelo olusha lokwelapha, i-China ibamba iqhaza elikhulu endaweni yomhlaba wonke ye-immunotherapy yomdlavuza, ithuthukisa izindlela zokwelapha iziguli ezweni lonke.
Hlola imininingwane
Ukwelashwa kwe-CAR T-Cell kwa-Israyeli
Kwa-Israel, ukwelashwa kwe-CAR T-cell kuye kwavela njengendlela yokuguqula ekulweni nomdlavuza. Umkhakha wezokunakekelwa kwempilo wezwe, owaziwa ngocwaningo lwayo olusezingeni lomhlaba kanye nokusungula izinto ezintsha, wenze intuthuko enkulu ekuthuthukiseni nasekusebenziseni izindlela zokwelapha ze-CAR T-cell ezigulini ezinezifo ze-hematological kanye nezimila eziqinile. Izikhungo zezokwelapha ezihamba phambili nezinkampani ze-biotechnology kwa-Israel zibambe iqhaza ngenkuthalo ezivivinyweni zemitholampilo namaphrojekthi ocwaningo, zicindezela imingcele yokwelashwa kwe-CAR T-cell. Imvelo yokusebenzisana yakwa-Israyeli kanye nobuchwepheshe obuphambili buyibeke njengesidlali somhlaba wonke ekuthuthukiseni i-immunotherapy, ihlinzeka ngezindlela ezintsha zokwelapha nethemba ezigulini ezinomdlavuza, ekhaya nasemhlabeni jikelele.
Hlola imininingwane
I-CAR T-Cell therapy eSingapore
Ukwelashwa kwe-CAR T-cell kungenelele kakhulu endaweni yokunakekelwa kwezempilo yase-Singapore, kunikeze indlela ethembisayo yokwelashwa komdlavuza. Ingqalasizinda yezokwelashwa esezingeni eliphezulu kanye namakhono ocwaningo yenze ukuthi kuthuthukiswe kanye nokusetshenziswa kwalokhu kwelashwa kokuzivikela komzimba okuphambili. Iziguli eSingapore manje sezinokufinyelela ekwelashweni kwe-CAR T-cell komdlavuza wegazi ohlukahlukene, okumaka ushintsho oluguquguqukayo ekunakekelweni kwe-oncology. Izikhungo zokunakekelwa kwezempilo zasendaweni zibambe iqhaza ekuhlolweni kwemitholampilo kanye nokusebenzisana nochwepheshe bomhlaba wonke, ukuqinisekisa ukuthi iziguli zithola ukwelashwa okusezingeni lomhlaba. Ngokuzibophezela kwayo ekusungulweni nasekunakekeleni isiguli, iSingapore idlala indima ebalulekile ekuthuthukiseni ukwelashwa kwe-CAR T-cell, okuhlinzeka ngethemba elisha ezigulini ezinomdlavuza esifundeni nangale kwayo.
Hlola imininingwane
ICancerFax: Ukunika Izimpilo Amandla, Ukuguqula Uhambo
"Owethu umbono wukuhola indlela yokuguqula indlela yokwelashwa komdlavuza, kuqinisekiswe ukuthi wonke umuntu uyafinyelela ekunakekelweni okwenziwe ngokwezifiso, okuphelele, nozwela. Ngezixazululo ezintsha kanye nokuzinikela okungantengantengi, silwela ukuqeda izithiyo, sinikeze ithemba, futhi sibe neqhaza emhlabeni lapho umdlavuza ungelapheki nje kuphela, kodwa unqotshwa.”
Mission Statement
"Ku ICancerFax, umgomo wethu uwukuba ibhuloho phakathi kwabantu abaphethwe umdlavuza kanye nokwelashwa okuthuthukile okubafanele.”
Sizibophezele:
- 1. Izindlela eziqondene nawe: Ukuhlanganisa izindlela zokwelapha ezihambisana nezidingo ezihlukile zesiguli ngasinye.
- 2. I-Global Network: Ukwakha inethiwekhi yomhlaba wonke yama-oncologists aziwayo, izikhungo zokwelapha ezisezingeni eliphezulu, kanye nezinsizakalo ezisekelayo.
- 3. Ukunikeza Amandla Ngolwazi: Ukunikeza ulwazi oluphelele, olusesikhathini samanje.
- 4. Ukusekela Okunozwelo: Ukunikeza ukusekela okungokomzwelo nokungokoqobo.
- 5. Ukuqamba Nokucwaninga: Ukusebenzisana nezikhungo zocwaningo ezihamba phambili.
- 6. Ukumela Nokuqwashisa: Ukukhuthaza izinqubomgomo zokunakekelwa komdlavuza ezithuthukisiwe.
- 7. Ubuhle Bokuziphatha: Ukugcina izindinganiso zokuziphatha eziphakeme kakhulu.
"Ngokuzibophezela okungantengantengi, ukusungula izinto ezintsha, nomoya wozwelo, sifisa ukuchaza kabusha isimo sokwelashwa komdlavuza, sinikeze ithemba, ukuphulukiswa, kanye nekusasa eliqhakazile kubo bonke abathintwe umdlavuza."
Hlola imininingwane
nobufakazi
Zithini iziguli ngathi?
Siyabathanda abasebenzisi bethu ngoba bayasithanda. Bheka olunye uthando abasithumelele lona
“Ngibhala lobu bufakazi ukuze ngidlulise ukubonga kwami okukhulu ngokushintsha impilo engibe nayo nethimba leCancerFax, elangethula ngeCAR T-cell therapy eChina. Uhambo lwami lokulwa nomdlavuza lwashintsha ngendlela enethemba lapho ngingeniswa kulokhu kwelashwa okuyisisekelo, futhi bekuyinto emangalisayo. Ngaphambi kokwelashwa kwe-CAR T-cell, ngase ngikhathele ukwelashwa okuvamile ngaphandle kwempumelelo enkulu. Isimo sami sasinzima, nethemba lase lifiphala. Nokho, isinqumo sami sokwelashwa nge-CAR T-cell eShayina saba inguquko. Izinga lokunakekelwa nobungcweti engaluthola lalingavamile. Ithimba lezokwelapha lalingenalo nje kuphela ikhono eliphezulu kodwa futhi lalinobubele ngendlela emangalisayo, linginikeza ukusekelwa nokuqinisekiswa engangikudinga phakathi nalesi sikhathi esiyinselele.”
Bjorn Simenson
I-Multiple Myeloma Survivor, eNorway
Imibuzo ejwayelekile ukubuzwa.
Thola ngezansi izimpendulo zemibuzo evame kakhulu iziguli ezinayo mayelana nokwelashwa komdlavuza.
Yiziphi ezinye izindlela zokwelapha ezithuthukisiwe ezitholakalayo zomdlavuza?
Izinketho ezithuthukisiwe zokwelapha umdlavuza zihlanganisa:
I-Immunotherapy: Lokhu kwelashwa kusebenzisa amasosha omzimba ukulwa namaseli omdlavuza. Ingasebenza kahle kakhulu kumdlavuza othile ngokukhuphula izinga lokuzivikela komzimba kumaseli omdlavuza.
Ukwelapha Okuhlosiwe: Lokhu kuhilela izidakamizwa eziqondise ngokuqondile ukuguqulwa kofuzo noma okungavamile ngaphakathi kwamaseli omdlavuza, ukunciphisa ukulimala kwamaseli anempilo.
Umuthi Wokunemba: Ngokuhlaziya ufuzo lwesiguli kanye nezici zesimila, odokotela bangakwazi ukuklama ukwelashwa kwezinhlobo ezithile zomdlavuza, okuholela emiphumeleni ephumelela kakhudlwana.
I-CAR T-cell Therapy: Lokhu kwelashwa okusha kuhilela ukuguqula izakhi zofuzo ama-T-cell esiguli ukuze abone futhi ahlasele amangqamuzana omdlavuza, ikakhulukazi kumdlavuza wegazi njenge-leukemia, i-myeloma eminingi, ne-lymphoma.
Yiziphi izinzuzo zokwelapha umdlavuza oseqophelweni eliphezulu uma kuqhathaniswa nemithi yesintu?
Ukwelashwa komdlavuza okuthuthukisiwe kunikeza izinzuzo ezimbalwa:
Ukusebenza Okuthuthukisiwe: Izindlela zokwelapha ezihlosiwe kanye nama-immunotherapies ngokuvamile asebenza kangcono futhi anembe, okuholela emiphumeleni engcono kanye nemiphumela engemihle embalwa.
Indlela Eqondene nawe: Ukwelashwa okuthuthukisiwe kuvame ukuvunyelaniswa nephrofayili yomuntu yofuzo kanye namangqamuzana, okwandisa ukusebenza kahle kuyilapho kunciphisa ukwelashwa okungadingekile.
Imiphumela Emibi Encishisiwe: Uma kuqhathaniswa nokwelashwa ngamakhemikhali okungokwesiko kanye nemisebe, izindlela zokwelapha ezithuthukisiwe zingaba nemiphumela engemihle embalwa, ethuthukisa izinga lokuphila ngesikhathi sokwelashwa.
Amazinga Okusinda Anyusiwe: Imithi eminingi ethuthukisiwe ibonise ukuthi ithuthukisa kakhulu amazinga okusinda kanye nemiphumela yesikhathi eside, ikakhulukazi ezimeni zomdlavuza osezingeni eliphezulu noma we-metastatic.
Iziguli zingafinyelela kanjani ekwelashweni nokwelashwa komdlavuza okuthuthukile?
Ukufinyelela ekwelashweni okuthuthukisiwe komdlavuza kuhilela izinyathelo ezimbalwa:
ICancerFax: Sithumelele imibiko yakho yezokwelashwa nge-imeyili noma ku-WhatsApp futhi ithimba lethu lezokwelapha lizokuqondisa ngezinketho ezitholakalayo ezingcono kakhulu zokwelapha umdlavuza.
Ukubonisana ne-Oncologist: Iziguli kufanele zixoxe ngezinketho zokwelapha ezithuthukisiwe nodokotela wazo we-oncologist, onganikeza ulwazi ngemithi etholakalayo kanye nokufaneleka kwamacala ngamanye.
Izivivinyo zemitholampilo: Ukubamba iqhaza ezivivinyweni zomtholampilo kunganikeza ukufinyelela ekwelashweni okuphambili okungakatholakali kabanzi.
Umshuwalense Wezempilo: Iziguli kufanele zihlole nomhlinzeki wazo womshwalense wezempilo ukuze ziqonde ukuhlinzekwa kokwelashwa okuthuthukile nezindleko ezihambisanayo.
Ukudluliselwa Ezikhungweni Ezikhethekile: Ukudluliselwa ezikhungweni ezikhethekile zomdlavuza noma izibhedlela ezaziwa ngokunakekela umdlavuza okuthuthukisiwe kungaqinisekisa ukufinyelela ezinhlobonhlobo zezinketho zokwelapha.
Amaqembu Okumela Iziguli: Lawa maqembu angahlinzeka ngezinsiza, ukwesekwa, kanye nolwazi lokufinyelela ekwelashweni okuthuthukile nokuzulazula ohlelweni lokunakekelwa kwezempilo ngempumelelo. Joyina iqembu lethu le-Facebook, Ukunqoba umdlavuza.
Ngingazithola kanjani izibhedlela e-USA ezinikeza ukubonisana ngomdlavuza ku-inthanethi?
ICancerFax ixhunywe kwezinye zezibhedlela ezihamba phambili zomdlavuza emhlabeni kanye nase-USA. Hlola uhlu lwethu lwezibhedlela ngenhla bese ukhetha esifanelana nezidingo zakho. Ithimba lethu lezokwelapha lingakusiza futhi ukuthi ukhethe leyo ehambisana nezidingo zakho nezidingo zakho. Bheka uhlu lwe- izibhedlela ezihamba phambili zomdlavuza e-USA. .
Yiluphi ulwazi noma amarekhodi ezokwelapha engiwadingayo ukuze ngibonise umdlavuza ku-inthanethi?
Udinga ukuhlinzeka ngamarekhodi ezempilo alandelayo:
- 1. Isifinyezo sezokwelapha
- 2. Iskena se-PET CT sakamuva
- 3. Imibiko yakamuva yegazi
- 4. Umbiko we-Biopsy
- 5. I-Bone marrow biopsy (Okweziguli ezinomdlavuza wegazi)
- 6. Zonke izikena ngefomethi ye-DICOM
Kuyini ukubonisana nomdlavuza ku-inthanethi?
Ukubonisana nomdlavuza ku-inthanethi kubhekisela enqubweni yokuthola izeluleko zezokwelapha, ukuxilongwa, kanye nezincomo zokwelashwa ezindabeni eziphathelene nomdlavuza ngokusebenzisa izinkundla ezibonakalayo. Ivumela iziguli ukuthi zixhumane zikude nodokotela be-oncologists nabanye ochwepheshe bezokunakekelwa kwempilo ngezingcingo zevidiyo nobuchwepheshe be-telemedicine. Ukubonisana nge-inthanethi kunikeza lula nokufinyeleleka, ikakhulukazi kulabo abanezinkinga zokuhamba noma abahlala ezindaweni ezikude.
Kusebenza kanjani ukubonisana nomdlavuza ku-inthanethi?
Kusetshenziswa ubuchwepheshe be-telemedicine, ukubonisana nomdlavuza ku-inthanethi kuxhuma iziguli kanye nabasebenzi bezempilo ukude. Iziguli zingaxoxa ngokukhathazeka kwazo okuhlobene nomdlavuza, zabelane ngamarekhodi ezokwelapha, futhi zithole izeluleko zochwepheshe ngamakholi wevidiyo avikelekile noma izinkundla zokuxhumana ngocingo. Odokotela bangahlola ulwazi olunikeziwe bekude futhi banikeze ukuxilongwa, izincomo zokwelashwa, nokusekelwa okuqhubekayo. Uma kudingeka, ochwepheshe bangaphinde baxhumane nodokotela bendawo ukuze benze uhlelo lokwelapha olufaneleka kakhulu isiguli.
Ngingathola imiyalelo noma izincomo zokwelashwa ngokubonisana nomdlavuza ku-inthanethi?
Yebo, uthola incwadi kadokotela kanye nombiko ophelele/iphrothokholi ngesikhathi sokwelashwa okudingekayo.
Yiziphi izinto ezisetshenziswayo engizidingayo ukuze ngixoxisane nomdlavuza ku-inthanethi?
Awudingi noma yimiphi imishini yokubonisana nge-inthanethi; udinga nje ukubonisana nge-pathology kanye nombiko obhaliwe. Ukuze uthole ukubonisana ngevidiyo nocingo, uzodinga ifoni ehlakaniphile enejubane elihle le-inthanethi.
Kuyini ukwelashwa kwe-CAR T-cell, futhi kusebenza kanjani?
I-CAR T-cell therapy, noma i-chimeric antigen receptor T-cell therapy, iyindlela emisha yokuzivikela komzimba. Kuhilela ukuqoqa amaseli e-T esiguli, ukuwaguqula ukuze aqondise kumaseli omdlavuza ngempumelelo, bese ebuyisela la maseli ashintshiwe emzimbeni wesiguli. Amaseli e-CAR T angakwazi ukubona futhi ahlasele amaseli omdlavuza ngokunemba. Bheka imininingwane ephelele ngokwelashwa kwe-CAR T-Cell. .
Ubani ofanelekela ukwelashwa kwe-CAR T-cell?
Ukufaneleka kokwelashwa kwe-CAR T-cell kuncike ezintweni ezihlukahlukene, okuhlanganisa uhlobo lomdlavuza, isigaba sawo, kanye nempilo yesiguli iyonke. Ngokuvamile, ukwelashwa kwe-CAR T-cell kucatshangelwa iziguli ezinezinhlobo ezithile zomdlavuza wegazi obuyele emuva noma ophikisanayo, njenge-leukemia noma i-lymphoma, ezingazange ziphendule ekwelashweni okujwayelekile. I-oncologist yakho izohlola icala lakho elithile ukuze inqume ukufaneleka.
Yimiphi imiphumela emibi engaba khona kanye nezingozi zokwelashwa kwe-CAR T-cell?
Ukwelashwa kwe-CAR T-cell kungaba nemiphumela engemihle, okuhlanganisa i-cytokine release syndrome (CRS) nemiphumela emibi ye-neurologic. I-CRS ingabangela umkhuhlane, izimpawu ezinjengomkhuhlane, futhi, ezimweni ezimbi kakhulu, ukungasebenzi kwezitho zomzimba. Imiphumela emibi ye-Neurologic ingase ihlanganise ukudideka noma ukuquleka. Ochwepheshe bezokunakekelwa kwempilo baqapha ngokucophelela futhi balawula le miphumela engemihle. Kubalulekile ukuxoxa ngezingozi nezinzuzo ezingaba khona nethimba lakho lezokwelapha.
Kuyini ukuhlola komtholampilo, futhi kungani kufanele ngicabange ukuhlanganyela koyedwa?
Ukuhlolwa komtholampilo wucwaningo locwaningo oluklanyelwe ukuhlola izindlela zokwelapha ezintsha noma ukungenelela komdlavuza. Ngokubamba iqhaza, ungase uthole ukufinyelela kumithi yokwelapha esezingeni eliphezulu okungenzeka isebenze kangcono kunokwelashwa okujwayelekile. Izivivinyo zemitholampilo nazo zinomthelela ekuthuthukiseni ulwazi lwezokwelapha kanye nokwenza ngcono ukunakekelwa komdlavuza esikhathini esizayo.
Ngingasithola kanjani isilingo somtholampilo esingifanele?
Ungaqala ngokuxoxa ngezinketho zesilingo somtholampilo nodokotela wakho we-oncologist noma umhlinzeki wezempilo. Bangancoma izivivinyo ngokusekelwe ohlotsheni lwakho oluthile lomdlavuza, isigaba, nomlando wezokwelapha. Ukwengeza, amawebhusayithi afana ne-ClinicalTrials.gov kanye nezinhlangano ezimelela isiguli ngokuvamile zihlinzeka ngemininingwane yolwazi eseshekayo yezilingo eziqhubekayo.
Yiziphi izingozi ezingaba khona kanye nezinzuzo zokubamba iqhaza ocwaningweni lomtholampilo?
Izinzuzo zingase zihlanganise ukufinyelela ekwelashweni okusha, ukuqapha okuseduze kwezokwelapha, kanye nemiphumela engase ibe ngcono. Izingozi zingahluka kodwa zingabandakanya imiphumela engemihle evela ekwelashweni kokuhlola noma ithuba lokuthi ukwelashwa okusha kungasebenzi kanye nokunakekelwa okujwayelekile. Kubalulekile ukuxoxisana ngokugcwele kokubili izingozi nezinzuzo nethimba lakho lezempilo ngaphambi kokwenza isinqumo.
Ingabe ngizothola i-placebo esivivinyweni somtholampilo?
Akuzona zonke izivivinyo zomtholampilo ezisebenzisa ama-placebo, futhi eziningi zibandakanya ukuqhathanisa ukwelashwa kokuhlola nezinga lamanje lokunakekela. Uma kusetshenziswa i-placebo, ababambiqhaza baziswe kusengaphambili, futhi imihlahlandlela yokuziphatha iqinisekisa ukuthi akekho owenqatshelwe ukwelashwa okudingekayo. Ithimba lakho lezokunakekelwa kwempilo lizochaza idizayini yesilingo kanye nokuthi i-placebo iyabandakanyeka yini.
Ingabe izivivinyo zomtholampilo ziphephile, futhi bavikelwa kanjani ababambiqhaza?
Ukuhlolwa kwemitholampilo kwenziwa ngokugcizelela kakhulu ukuphepha kwesiguli. Amakomiti okuziphatha nezinhlangano ezilawulayo ziwaqapha eduze futhi aphoqelele izimiso eziyisisekelo. Uzokwaziswa ngezingozi ezingaba khona futhi uqashwe kulo lonke ucwaningo. Ungahoxa esivivinyweni nganoma yisiphi isikhathi uma unokukhathazeka mayelana nokuphepha noma ezinye izinkinga.
Ingabe ukubamba iqhaza esivivinyweni somtholampilo kuzongibiza imali, futhi ingabe umshwalense wami uzoyikhokhela?
Ngokuvamile, umxhasi wesilingo somtholampilo unesibopho sokumboza izindleko zokwelashwa kokuhlola kanye nokuhlola okuhlobene nocwaningo. Kodwa-ke, ungase ube nesibopho sezindleko zokwelashwa ezijwayelekile ezingahlobene nokuhlola, njengokuvakashela odokotela okuvamile noma ukwelapha okungekhona okokuhlola. Kubalulekile ukuxoxa ngezici zezezimali nomxhumanisi wesilingo kanye nomhlinzeki wakho womshwalense ukuze uqonde ukuthi yini ekhavayo kanye nanoma yiziphi izindleko ezingaba khona eziphuma ephaketheni. Izinhlelo eziningi zomshwalense manje zimboza izindleko ezijwayelekile zokubamba iqhaza kocwaningo lomtholampilo.
Ingabe i-CAR T-cell therapy iwukwelashwa kwesikhathi esisodwa, noma ngizodinga ukufakwa okuningi?
Ukwelashwa kwe-CAR T-cell kuvamise ukuba ukwelashwa kwesikhathi esisodwa. Kodwa-ke, ezinye iziguli zingase zidinge ukuthakwa okwengeziwe noma ezinye izindlela zokwelapha uma umdlavuza wazo ubuyela emuva noma uma kunesidingo sokunakekelwa kokulandelela isikhathi eside. Uhlelo lwakho lokwelapha luzofanelana nesimo sakho esithile.
Yini engingayilindela ngemva kokwelashwa kwe-CAR T-cell, futhi lingakanani izinga lempumelelo?
Ngemuva kokwelashwa kwe-CAR T-cell, uzogadwa eduze ukuze uthole imiphumela engemihle engaba khona kanye nokuhlola ukusebenza kokwelashwa. Amazinga empumelelo angahluka kuye ngohlobo nesigaba somdlavuza. Ukwelashwa kwe-CAR T-cell kubonise imiphumela ethembisayo kwezinye iziguli ezinomdlavuza wegazi obuye wabuyela emuva noma ongashintshi, okuholela ekukhululweni okuphelele. Nokho, izimpendulo ngazinye zingahluka, futhi kubalulekile ukuxoxa ngesifo sakho nethimba lakho lezokwelapha.
Ingabe i-CAR T-Cell therapy iyatholakala eNdiya?
Yebo, ezinye izinkampani seziqalile Ukwelashwa kwe-CAR T-Cell eNdiya ngosizo lwama-vector avela e-China naseMalaysia. Nokho, lokhu kwelashwa kusengaphansi kokuhlolwa komtholampilo. Amafomu emvume yesiguli kanye nezeluleko zikadokotela ziyacelwa ngaphambi kokuthi uye kulezi zivivinyo.
Ziyini izindleko zokwelashwa kwe-CAR T-Cell?
Izindleko zokwelashwa kwe-CAR T-cell ziyahlukahluka kuye ngamazwe. Nazi izindleko ezilinganiselwe emazweni ahlukene. I-USA- $ 600,000-700,000 USD E-China – $ 60,000-90,000 USD India – $ 60,000-90,000 USD Israel – $ 85,000-100,000 USD Singapore – $ 700,000-750,000 SGD
Yiziphi izinhlobo zomdlavuza ezifanelekela ukwelashwa kwe-CAR T-Cell eChina?
E-China, ukwelashwa kwe-CAR T-cell kuvunyelwe ngokuyinhloko futhi kusetshenziselwe ukwelapha izifo ze-hematological, ezifana i-lymphoma, i-leukemia, ne-myeloma.
Yize kukhona ezinye izivivinyo zemitholampilo nemizamo yocwaningo ehlola ukwelashwa kwe-CAR T-cell yamathumba aqinile, inqubekelaphambili kule ndawo ihambe kancane uma iqhathaniswa ne-hematological malignancies.
Ngokolwazi olutholakalayo, izindlela zokwelapha ze-CAR T-cell zamathumba aqinile zenza u-9% kuphela wengqikithi yokwelashwa kwe-CAR T-cell eyenziwa eChina.
Isebenza kanjani i-CAR T Cell Therapy e-China uma iqhathaniswa nezinye izindlela zokwelapha?
Ukusebenza kokwelashwa kwe-chimeric antigen receptor T-cell (CAR-T) e-China kuqhathaniswe nezinye izindlela zokwelapha ngokuhlolwa okubanzi kwemitholampilo nocwaningo. Kusukela ngo-2022, i-China inenani elikhulu lezifundo zomtholampilo ze-CAR-T kune-United States, ikakhulukazi ezifweni ze-hematological. Izindlela zokwelapha ezimbili ze-CAR-T, i-axicabtagene ciloleucel (Yescarta) kanye ne-relmacabtagene autoleucel (Carteyva), zigunyazwe e-China yi-National Medical Products Administration (NMPA). Ukwelashwa kwe-CAR-T e-China kubonise ukusebenza ngempumelelo ezinkingeni ezihlukahlukene ze-hematological, okuhlanganisa i-B-cell acute lymphoblastic leukemia (ALL), i-lymphoma, ne-multiple myeloma (MM). Nokho, izinselele zisekhona, njengezindleko eziphezulu, inqubo yokukhiqiza edla isikhathi, kanye nezenzakalo ezimbi ezihlobene nokuzivikela komzimba. Ukuze kubhekwane nalezi zinkinga, abacwaningi baseShayina bakha amasu okuthuthukisa ukwelashwa kwe-CAR-T, okuhlanganisa ukuthuthukiswa kwemikhiqizo ye-allogeneic CAR-T kanye nokusetshenziswa kwezinye izizinda ze-costimulatory. Kafushane, ukwelashwa kwe-CAR-T e-China kubonise imiphumela ethembisayo ku-hematological malignancies, ngenani elikhulu lezivivinyo zomtholampilo uma kuqhathaniswa ne-United States. Kodwa-ke, izinselelo zisekhona, futhi ucwaningo olwengeziwe luyadingeka ukuze kwandiswe ukwelashwa futhi andise ukusetshenziswa kwakho kube izimila eziqinile.
Zingakanani izindleko zokwelashwa kwe-CAR T Cell e-China?
Izindleko zokwelashwa kwe-CAR T-Cell e-China ziyehluka phakathi 45,000 USD kanye 90,000 USD. Izindleko zizonke zincike esibhedlela esikhethiwe kanye nenani lama-antigen okuhlosiwe akhethiwe. Izindleko zemithi yokwelapha yamaseli e-CAR-T egunyaziwe e-China ngokuvamile icishe ibe yi-1,200,000 yama-yuan yesiShayina (CNY), okulingana cishe no-$170,000. Izindleko ze-Cilta-Cel, FUCASO (i-NMPA-igunyazwe) ye-myeloma eminingi ziyahlukahluka phakathi I-250,000 ne-300,000 USD. Ukusebenza kahle kwezindleko zokwelashwa kwamaseli e-CAR-T e-China kuyehluka kuye ngokwelashwa okuqondile kanye nesimo sesiguli.
Konke okudingeka ukwazi ngakho
izinhlobo ezahlukene zomdlavuza
Izibhedlela Eziphezulu Zomdlavuza
ESTD: 1941
Inombolo yemibhede: 1200
MD Anderson Cancer Centre, USA
I-MD Anderson Cancer Center iyinhlangano eyaziwayo ehola umhlaba wonke ekwelapheni umdlavuza, ucwaningo, kanye nemfundo. Yasungulwa ngo-1941 futhi izinze eHouston, eTexas. Sekuyisikhathi eside ihola ocwaningweni nokwelashwa komdlavuza. Lesi sikhungo siqanjwe ngoMonroe Dunaway Anderson, usomabhizinisi ocebile futhi osiza umphakathi owayenombono wokwakha isikhungo somdlavuza esizoletha izinguquko endleleni umdlavuza oqondwa futhi welashwe ngayo.
ESTD: 2001
Inombolo yemibhede: 380
Isikhungo Somdlavuza saseParkway, eSingapore
Izibhedlela zaseParkway ziheha iziguli zakwamanye amazwe ngenxa yezikhungo zazo zezokwelapha ezisezingeni lomhlaba kanye nobuchwepheshe. I-Parkway Hospitals ingumhlinzeki wezempilo ozimele omkhulu kunabo bonke e-Asia.
ESTD: 2003
Inombolo yemibhede: 400
Isibhedlela saseBeijing Gobroad, eChina
Isibhedlela i-Beijing Gobroad Boren yisikhungo sezokwelapha esizimele esizinikele kubuchwepheshe bezokwelapha obusezingeni eliphezulu, ukunakekelwa kozwela, nokwaneliseka kwesiguli, esibeka kuqala inhlalakahle yeziguli ngaphezu kwakho konke okunye. Sihlanganisa isistimu yolwazi oluthuthukisiwe, izinqubo zokuxilonga nokwelashwa, ukuqeqeshwa kwezokwelapha okusimeme, imfundo yesiguli, ukuphathwa kwesibhedlela, nomqondo wesevisi ovela eqenjini lezokwelapha lezinga eliphezulu e-United States, i-Mayo Clinic.
Ama-Oncologists aphezulu
UDkt Ang Peng Tiam
Singapore
UProfesa Arnon Nagler
I-Tel Aviv, i-Israel
UProfesa Peihua Peggy Lu
Beijing, eChina
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