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Breakthrough Treatments for Advanced Breast Cancer in 2025

Latest breakthroughs in the treatment of breast cancerBy 2025, the domain of advanced breast cancer treatment is swiftly transforming, providing renewed optimism to patients globally. Recent advanceme...
immunotherapy

Neoadjuvant and adjuvant pembrolizumab is approved by the USFDA for resectable locally advanced head and neck squamous cell carcinoma

On June 12, 2025, the Food and Drug Administration approved pembrolizumab (Keytruda, Merck) for adults with advanced head and neck squamous cell carcinoma (HNSCC) that can be surgically removed and sh...
immunotherapy

Atezolizumab Plus Chemotherapy Improves Survival in Advanced-Stage Small-Cell Lung Cancer: Insights from the IMpower133 Study

IMPower133 study The IMpower133 study has brought significant advancements in the treatment of advanced-stage small-cell lung cancer (ES-SCLC). By combining atezolizumab, a type of immunotherapy, wit...
immunotherapy

Retifanlimab-dlwr with carboplatin and paclitaxel is approved by the USFDA and as a single agent for squamous cell carcinoma of the anal canal

On May 15, 2025, the Food and Drug Administration sanctioned retifanlimab-dlwr (Zynyz, Incyte Corporation) in conjunction with carboplatin and paclitaxel for the initial treatment of people with inope...
immunotherapy

Penpulimab-kcqx is approved by the USFDA for non-keratinizing nasopharyngeal carcinoma

On April 23, 2025, the Food and Drug Administration sanctioned penpulimab-kcqx (Akeso Biopharma Co., Ltd.) in conjunction with cisplatin or carboplatin and gemcitabine for the initial treatment of peo...
immunotherapy

Cosibelimab-ipdl is approved by the USFDA for metastatic or locally advanced cutaneous squamous cell carcinoma

 On December 13, 2024, the Food and Drug Administration sanctioned cosibelimab-ipdl (Unloxcyt, Checkpoint Therapeutics, Inc.), a programmed death ligand-1 (PD-L1) inhibiting antibody, for adults with...
immunotherapy

Durvalumab is approved by the USFDA for limited-stage small cell lung cancer

 On December 4, 2024, the Food and Drug Administration sanctioned durvalumab (Imfinzi, AstraZeneca) for adults with limited-stage small cell lung cancer (LS-SCLC) whose condition remains stable after...
immunotherapy

Enhancing Cancer Outcomes: The Critical Role of Early CAR T-Cell Therapy

Cancer remains one of the most challenging diseases to treat, requiring innovative and effective therapies. One of the most promising advancements in cancer treatment is Chimeric Antigen Receptor (CA...
immunotherapy

Obecabtagene autoleucel for adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia

On November 8, 2024, the Food and Drug Administration sanctioned obecabtagene autoleucel (Aucatzyl, Autolus Inc.), a CD19-targeted genetically engineered autologous CAR T cell therapy, for people with...
immunotherapy

Neoadjuvant/adjuvant nivolumab is approved by the USFDA for resectable non-small cell lung cancer

 On October 3, 2024, the Food and Drug Administration sanctioned nivolumab (Opdivo, Bristol Myers Squibb Company) in conjunction with platinum-doublet chemotherapy as neoadjuvant therapy, succeeded b...
immunotherapy

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