Introduction CAR T cell therapy is a nascent cancer treatment that targets and eliminates cancerous cells by using the body's immune system. Gene modification is done for the expression of chimeric a...
Two types of T-cells There exist two distinct categories of T cells: αβ T cells and γδ T cells. The previous statement describes a T-cell receptor (TCR) that consists of a heterodimer composed of...
CAR T-Cell treatment Chimeric Antigen Receptor (CAR) T-cell treatments, which target antigens that are unique to cancer, have shown amazing results in curing leukemia and lymphoma that has not respon...
CAR T-Cell therapy in the treatment of cancer A preclinical study conducted by researchers at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center suggests that the...
Introduction Chronic lymphocytic leukemia (CLL) is a long-lasting condition where mature B lymphocytes, which have encountered antigens before, become cancerous. This leads to the buildup of malignan...
May 2024: The Food and Drug Administration has granted approval to lisocabtagene maraleucel (Breyanzi, Juno Therapeutics, Inc.) for the treatment of adult patients with relapsed or refractory mantle c...
June 2024: The chances of getting secondary blood cancers after CAR-T cell therapy, a cell-based cancer treatment that got a lot of attention in 2017 for being effective against hard-to-treat blood ca...
June 2024: Seattle Children's Hospital will initiate the inaugural clinical trial in the United States this summer to evaluate the efficacy of an autologous CAR T-cell treatment against a prevalent ki...
What is the Richter transformation? Richter transformation is an infrequent but not rare occurrence when an aggressive B-cell lymphoma develops in people with chronic lymphocytic leukemia or small ly...
Pancreatic cancer Pancreatic cancer, also referred to as the "king of cancers," is a highly deadly malignant tumor, with a survival rate of fewer than 10% over a 5-year period. As a result of inadequ...