Introduction: What is the PiggyBac Transposon System? The PiggyBac transposon system is a non-viral gene delivery tool that enables the insertion of specific genes into host genomes. Originally discov...
Introduction Chimeric Antigen Receptor (CAR) T-cell therapy has already transformed the landscape of cancer treatment. Now, the 4th generation CAR T-cell therapy, augmented with interleukin-15 (IL-15...
Gene Therapy for Gaucher’s Disease in ChinaGaucher's disease is a rare inherited condition that happens when the body doesn't have enough of the glucocerebrosidase (GBA) enzyme, leading to harmful f...
IntroductionLiver transplant surgery has seen tremendous progress in the last few decades, transforming the therapeutic possibilities of patients with end-stage liver disease, acute liver failure, and...
CAR T Cell therapy in KoreaCAR T cell therapy is an advanced cancer treatment that has gained significant momentum in South Korea. It involves genetically modifying a patient’s T cells to recognize ...
What is gene therapy? Gene therapy acts as the lighthouse of contemporary medicine by offering to help correct hereditary afflictions at their very roots—the genome itself. Such treatment involves ...
History and Evolution of Gene Therapy The history and development of gene therapy, a radically new medical intervention that intends to treat or prevent diseases by modifying the genetic material wit...
Genetic disorders and gene therapy Gene therapy has transformed the concept of treatment for a genetic disorder, thus giving hopes to millions across the globe. Therefore, regarding biomedical resear...
FDA approval of gene therapy The FDA has made it possible for people 12 years of age and older who have transfusion-dependent beta-thalassemia (TDT) to use exagamglogene autotemcel (Casgevy, Vertex)....
USFDA approved gene therapy for sickle cell disease The U.S. Food and Drug Administration has granted approval for two significant medications, Casgevy and Lyfgenia, which are the first gene therap...