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Dr. Zhang Wei: Leading Innovation in Epigenetic Therapy for Diffuse Midline Glioma at Tsinghua University

IntroductionDiffuse midline glioma (DMG) remains one of the most aggressive and devastating brain tumors in children and young adults. Surgical removal is often impossible due to its deep-seated midli...

Epigenetic Agent-Based Immunotherapy Shows Promise in Diffuse Midline Glioma

Diffuse midline glioma (DMG), specifically the H3K27-mutated subtype, is among the most malignant and lethal types of pediatric-type brain tumors. Marked by poor prognosis and ineffectiveness to tradi...

ONC201 Capsules: A New Hope for Brain Glioma Patients in China

Gliomas IntroductionBrain gliomas, especially aggressive types such as glioblastoma multiforme (GBM), have long been extremely challenging to treat because of their insensitivity to traditional therap...

Latest therapies in the treatment of hematological malignancies

 IntroductionHematological malignancies, such as leukemias, lymphomas, and multiple myeloma, are a heterogeneous group of cancers that arise in the bone marrow and lymphatic system. Conventional trea...

Limkato: Korea’s first CAR T Cell therapy

CAR T Cell therapy in KoreaCAR T cell therapy is an advanced cancer treatment that has gained significant momentum in South Korea. It involves genetically modifying a patient’s T cells to recognize ...

The FDA has granted approval for the use of vorasidenib in the treatment of Grade 2 astrocytoma or oligodendroglioma in patients having a specific IDH1 or IDH2 mutation

August 2024: Vorasidenib (Voranigo, Servier Pharmaceuticals LLC), an inhibitor of isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2), has been approved by the Food and Drug Admini...

The FDA has granted accelerated approval to afamitresgene autoleucel for the treatment of unresectable or metastatic synovial sarcoma

August 2024: The Food and Drug Administration has given accelerated approval to afamitresgene autoleucel (TECELRA, Adaptimmune, LLC), a genetically modified autologous T cell immunotherapy that target...

The FDA has broadened the indication for dostarlimab-gxly to include the treatment of endometrial cancer in combination with chemotherapy

August 2024: The Food and Drug Administration has granted approval for dostarlimab-gxly (Jemperli, GSK) in combination with carboplatin and paclitaxel, followed by single-agent dostarlimab-gxly, for t...

Toripalimab-tpzi is approved by the FDA for nasopharyngeal carcinoma

In October 2023, the FDA approved toripalimab-tpzi (LOQTORZ, Coherus BioSciences, Inc.) with cisplatin and gemcitabine as the first-line treatment for people with locally advanced nasopharyngeal canc...

Mesenchymal stem cells (MSC) and platelet-rich plasma (PRP) therapy in the treatment of knee osteoarthritis

Feb 2024: Mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) therapy have shown potential in treating knee osteoarthritis (KOA) in China. A meta-analysis of randomized controlled studies lo...

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