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Seattle Children’s Hospital to Start CAR T-Cell Clinical Trial for Pediatric Lupus Patients

June 2024: Seattle Children's Hospital will initiate the inaugural clinical trial in the United States this summer to evaluate the efficacy of an autologous CAR T-cell treatment against a prevalent ki...

Efficacy of CAR T Cell Therapy in B-Cell lymphoma Richter Transformation

What is the Richter transformation? Richter transformation is an infrequent but not rare occurrence when an aggressive B-cell lymphoma develops in people with chronic lymphocytic leukemia or small ly...

Claudin18.2-targeted CAR-T cell therapy brings complete remission in advanced pancreatic cancer patient : A case report

Pancreatic cancer Pancreatic cancer, also referred to as the "king of cancers," is a highly deadly malignant tumor, with a survival rate of fewer than 10% over a 5-year period. As a result of inadequ...

What is the treatment after BCMA CAR T failed in R/R multiple myeloma cases?

OriCAR-017 for RRMM A top biopharmaceutical company in the clinical stage, Oricell Therapeutics, shared the long-term follow-up results of OriCAR-017, a Phase I study that looked at how well GPRC5D-t...

CARSgen presents latest data of Satri-cel therapy in ASCO 2024

Results of SATRi-cel therapy CARsgen Therapeutics Holdings Limited (Stock Code: 2171.HK) has released the latest findings from the investigator-initiated trial CT041-CG4006 (NCT03874897) of satricabt...

Can CAR T cell therapy shortcomings be avoided by NK Cell therapy?

NK Cell therapy vs CAR T-Cell therapy The FDA's approval of the first CAR T cell therapy in 2017 was widely celebrated as a significant advancement in cancer treatment. The method enabled a focused a...

CAR T Cell therapy for refractory systemic lupus erythematosus in China

What is systemic lupus erythematosus? Systemic lupus erythematosus (SLE) is defined by an abnormal immune response, resulting in a highly varied clinical presentation that can potentially impact many...

Zevorcabtagene autoleucel (Zevra-cel therapy) approved for R/R multiple myeloma

SHANGHAI, China, April 30, 2024, CARsgen Therapeutics Holdings Limited (Stock Code: 2171.HK), a company focused on innovative CAR T-cell therapies for the treatment of hematologic malignancies and sol...

After amazing growth of CAR T-Cell therapy: what’s next?

The future of CAR T-cell therapy: an analysis of its rapid growth and expansion. Within the realm of contemporary medicine, CAR T-cell therapy emerges as an innovative and groundbreaking intervention...

Human-Based CAR T Cell Therapy: Breakthroughs and Challenges

Introduction In the domain of oncology, immunotherapy has emerged as a pioneering methodology, harnessing the body's immune system to combat malignant tumors. There are many immunotherapeutic approac...

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