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trifluridine and tipiracil
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Trifluridine and tipiracil with bevacizumab is approved by FDA for previously treated metastatic colorectal cancer

August 2023: For metastatic colorectal cancer (mCRC) that has already been treated with fluoropyrimidine, oxaliplatin, and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy..

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