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Teclistamab-cqyv is approved by FDA for relapsed or refractory multiple myeloma

November 2022: The first bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager, teclistamab-cqyv (Tecvayli, Janssen Biotech, Inc.), was given accelerated approval by the Food and Dru...

Tremelimumab is approved by FDA in combination with durvalumab for unresectable hepatocellular carcinoma

November 2022: The Food and Drug Administration approved tremelimumab (Imjudo, AstraZeneca Pharmaceuticals) in combination with durvalumab for adult patients with unresectable hepatocellular carcinoma...

Cccelerated approval is granted by FDA to futibatinib for cholangiocarcinoma

November 2022: The Food and Drug Administration granted accelerated approval to futibatinib (Lytgobi, Taiho Oncology, Inc.) for adult patients with previously treated, unresectable, locally advanced o...

Pemigatinib is approved for relapsed or refractory myeloid/lymphoid neoplasms with FGFR1 rearrangement

November 2022: Pemigatinib (Pemazyre, Incyte Corporation) has been licenced by the Food and Drug Administration for use in people with relapsed or refractory myeloid/lymphoid neoplasms (MLNs) that hav...

Claudin 18.2 and its role in advanced gastric cancers

August 2022: The most apical portion of polarized epithelial and endothelial cells contains tight junctions, which are specialized membrane domains. The claudins, which are important proteins in tigh...

Accelerated approval is granted by FDA to fam-trastuzumab deruxtecan-nxki for HER2-mutant non-small cell lung cancer

August 2022: For adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumours have a mutation resulting in mesenchymal-epithelial transition (MET) exon 14 skipping, as detected by ...

Capmatinib is approved for metastatic non-small cell lung cancer

August 2022: For adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumours have a mutation resulting in mesenchymal-epithelial transition (MET) exon 14 skipping, as detected by ...

Darolutamide tablets is approved by FDA for metastatic hormone-sensitive prostate cancer

August 2022: Darolutamide (Nubeqa, Bayer HealthCare Pharmaceuticals Inc.) tablets combined with docetaxel were approved by the Food and Drug Administration for adult patients with metastatic hormone-...

Lisocabtagene maraleucel is approved by FDA for second-line treatment of large B-cell lymphoma

July 2022:  Lisocabtagene maraleucel (Breyanzi, Juno Therapeutics, Inc.) has been approved by the Food and Drug Administration for adult patients with large B-cell lymphoma (LBCL) who have refractor...

All participants in a small cancer trial achieved complete remission

June 2022: A small study of rectal cancer patients yielded extraordinary results: 100 percent of the individuals were in remission. The results were published in The New England Journal of Medicine t...

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