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Remestemcel-L-rknd is approved by the USFDA for steroid-refractory acute graft versus host disease in pediatric patients

On December 18, 2024, the Food and Drug Administration sanctioned remestemcel-L-rknd (Ryoncil, Mesoblast, Inc.), an allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy, for steroid-r...

Ibrutinib is approved for pediatric patients with chronic graft versus host disease, including a new oral suspension

Sept 2022: Ibrutinib (Imbruvica, Pharmacyclics LLC) was approved by the Food and Drug Administration for use in paediatric patients with chronic graft versus host disease (cGVHD) who are younger than...

Abatacept is approved for prophylaxis of acute graft versus host disease

March 2022: Abatacept (Orencia, Bristol-Myers Squibb Company) has been approved by the Food and Drug Administration for the prevention of acute graft versus host disease (aGVHD) in adults and paediat...

Ruxolitinib is approved for chronic graft-versus-host disease

October 2021: After failure of one or two lines of systemic therapy, the Food and Drug Administration approved ruxolitinib (Jakafi, Incyte Corp.) for chronic graft-versus-host disease (cGVHD) in adult...

The FDA has approved belumosudil for the treatment of chronic graft-versus-host disease

August 2021: After failure of at least two prior lines of systemic therapy, the Food and Drug Administration approved belumosudil (Rezurock, Kadmon Pharmaceuticals, LLC), a kinase inhibitor, for adult...

Beta Thalassemia and its consideration with COVID-19

July 2021: Beta-thalassemia is an inherited condition caused by mutations in a gene involved in the production of a component of haemoglobin, the protein that transports oxygen throughout the body. Th...

Bone marrow stem cell transplant

Bone marrow transplant Bone marrow transplants are procedures that restore blood-forming stem cells in people who have had theirs destroyed by the very high doses of chemotherapy or radiation thera...

Bone marrow transplant in India

Bone marrow transplant in India Bone marrow stem cell transplants in India are performed by some of the leading cancer centres. To date, more than 10,000 successful bone marrow stem cell transplants ...

Bone marrow transplant in India – A patient story

This story is about bone marrow transplant in India. Mukhtar, who is from Assela in Ethiopia, suffers from deadly aplastic anemia. He travels to India for his stem cell transplant. Read the entire sto...

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