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Pembrolizumab is approved by the USFDA for HER2 positive gastric or gastroesophageal junction adenocarcinoma expressing PD-L1 (CPS ≥1)

On March 19, 2025, the Food and Drug Administration officially approved pembrolizumab (Keytruda, Merck) to be used along with trastuzumab and chemotherapy that includes fluoropyrimidine and platinum f...

Gene Therapy for Gaucher’s Disease in China

Gene Therapy for Gaucher’s Disease in ChinaGaucher's disease is a rare inherited condition that happens when the body doesn't have enough of the glucocerebrosidase (GBA) enzyme, leading to harmful f...

Gene Therapy for Wilson’s Disease in China

Gene Therapy for Wilson's Disease in China   Introduction Wilson’s disease is a rare genetic disorder that causes excessive copper accumulation in the liver, brain, and other vital organs. With...

Gene Therapy for Phenylketonuria in China

Gene Therapy for Phenylketonuria in China: A Breakthrough Treatment IntroductionPhenylketonuria (PKU) is a rare genetic disorder that affects the body's ability to break down phenylalanine (Phe), an ...

Datopotamab deruxtecan-dlnk is approved by the USFDA for unresectable or metastatic, HR-positive, HER2-negative breast cancer

On January 17, 2025, the Food and Drug Administration sanctioned datopotamab deruxtecan-dlnk (Datroway, Daiichi Sankyo, Inc.), a Trop-2-targeted antibody and topoisomerase inhibitor conjugate, for adu...

Advances in Liver Transplant Surgery: Techniques and Technologies

IntroductionLiver transplant surgery has seen tremendous progress in the last few decades, transforming the therapeutic possibilities of patients with end-stage liver disease, acute liver failure, and...

Ensartinib is approved by the USFDA for ALK-positive locally advanced or metastatic non-small cell lung cancer

 On December 18, 2024, the Food and Drug Administration sanctioned ensartinib (Ensacove, Xcovery Holdings, Inc.) for adult patients with anaplastic lymphoma kinase (ALK)-positive locally advanced or ...

Cosibelimab-ipdl is approved by the USFDA for metastatic or locally advanced cutaneous squamous cell carcinoma

 On December 13, 2024, the Food and Drug Administration sanctioned cosibelimab-ipdl (Unloxcyt, Checkpoint Therapeutics, Inc.), a programmed death ligand-1 (PD-L1) inhibiting antibody, for adults with...

Durvalumab is approved by the USFDA for limited-stage small cell lung cancer

 On December 4, 2024, the Food and Drug Administration sanctioned durvalumab (Imfinzi, AstraZeneca) for adults with limited-stage small cell lung cancer (LS-SCLC) whose condition remains stable after...

Zenocutuzumab-zbco is approved by the USFDA for non-small cell lung cancer and pancreatic adenocarcinoma

 On December 4, 2024, the Food and Drug Administration granted accelerated approval to zenocutuzumab-zbco (Bizengri, Merus N.V.) for use in adults with specific conditions.Patients with advanced, unr...

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