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Dr. Zhang Wei: Leading Innovation in Epigenetic Therapy for Diffuse Midline Glioma at Tsinghua University

IntroductionDiffuse midline glioma (DMG) remains one of the most aggressive and devastating brain tumors in children and young adults. Surgical removal is often impossible due to its deep-seated midli...

Epigenetic Agent-Based Immunotherapy Shows Promise in Diffuse Midline Glioma

Diffuse midline glioma (DMG), specifically the H3K27-mutated subtype, is among the most malignant and lethal types of pediatric-type brain tumors. Marked by poor prognosis and ineffectiveness to tradi...

Breakthrough in Cancer Treatment: FDA Approves Drug from Small Enterprise in Tianjin, China

Introduction In a stunning surprise that has stunned the international biotech industry, a tiny and micro business in Tianjin, China, has come up with an anti-cancer medication that just won official...

ONC201 Capsules: A New Hope for Brain Glioma Patients in China

Gliomas IntroductionBrain gliomas, especially aggressive types such as glioblastoma multiforme (GBM), have long been extremely challenging to treat because of their insensitivity to traditional therap...

4th Generation CAR T Cell Therapy with IL-15: A new era in cancer treatment

Introduction Chimeric Antigen Receptor (CAR) T-cell therapy has already transformed the landscape of cancer treatment. Now, the 4th generation CAR T-cell therapy, augmented with interleukin-15 (IL-15...

Nivolumab with ipilimumab is approved by the USFDA for unresectable or metastatic hepatocellular carcinoma

On April 11, 2025, the Food and Drug Administration sanctioned nivolumab (Opdivo, Bristol Myers Squibb Company) in conjunction with ipilimumab (Yervoy, Bristol Myers Squibb Company) for the first trea...

Nivolumab with ipilimumab is approved by the USFDA for unresectable or metastatic MSI-H or dMMR colorectal cancer

On April 8, 2025, the Food and Drug Administration approved nivolumab (Opdivo, Bristol Myers Squibb Company) and ipilimumab (Yervoy, Bristol Myers Squibb Company) for adults and children 12 years and ...

Durvalumab is approved by the USFDA for muscle invasive bladder cancer

On March 28, 2025, the Food and Drug Administration approved durvalumab (Imfinzi, AstraZeneca) to be used with gemcitabine and cisplatin as a first treatment, followed by durvalumab alone as a follow-...

The FDA has broadened the indication for Pluvicto to include metastatic castration-resistant prostate cancer

On March 28, 2025, the Food and Drug Administration expanded the use of lutetium Lu 177 vipivotide tetraxetan (Pluvicto, Novartis Pharmaceuticals Corporation) to include adults with prostate-specific ...

Cabozantinib is approved by the USFDA for adults and pediatric patients 12 years of age and older with pNET and epNET

On March 26, 2025, the Food and Drug Administration sanctioned cabozantinib (Cabometyx, Exelixis, Inc.) for adult and pediatric patients aged 12 and older with previously treated, unresectable, locall...

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