കുട്ടിക്കാലത്തെ കാൻസറിനുള്ള പുതിയ ജനിതക പരിശോധന

ബ്രിട്ടീഷ് ശാസ്ത്രജ്ഞർ കുട്ടിക്കാലത്തെ മുഴകളുടെ ജനിതക പരിശോധന ആരംഭിച്ചു. ജനിതക പരിശോധന ചെറുപ്പക്കാരായ രോഗികൾക്ക് അവരുടെ അതിജീവനം വർദ്ധിപ്പിക്കുന്ന പുതിയതും കൂടുതൽ വ്യക്തിഗതവുമായ ചികിത്സകൾ നൽകുമെന്ന് ബ്രിട്ടീഷ് ശാസ്ത്രജ്ഞർ പ്രതീക്ഷിക്കുന്നു. പുതിയ പരിശോധനയിൽ 81 വ്യത്യസ്ത കാൻസർ ജനിതകമാറ്റങ്ങൾ വിശകലനം ചെയ്യുന്നു.

Scientists say the test will lead to “a higher level of playing field” and accelerate children’s access to important new drug treatments. The test was performed at the Royal Marsden National Health System Hospital in London and will be tested on 400 children from all over the UK over the next two years.

The test has been implemented with genetic funding from the National Institutes of Health (NIHR) foundation and the കാൻസർ Institute. A charity called Christopher has provided more than £ 300,000 in funding to develop the test. The organization was founded by a couple whose children died of invasive മസ്തിഷ്ക മുഴകൾ at the age of six.

This is a real first step towards personalized കാൻസർ ചികിത്സ for children,” said Christopher’s parents, Karen and Kevin Capel. Christopher got a generic ട്യൂമർ. Hopefully, in the future, children will know exactly what type of tumor they have.” “We almost feel that the treatment for the child is not to kill the cancer, but to kill our child.”
“He used to be a healthy, happy, very athletic 4-year-old kid. But he became unable to speak or even eat on his own, and lost weight. “In the year he was diagnosed, he was unable to grow into a child of his age. We tried to keep him from other children.”

കുട്ടികളിൽ മാരകമായ മുഴകൾ വളരെ അപൂർവമാണ്, ധാരാളം രോഗികളുടെ ജനസംഖ്യയില്ല, കൂടാതെ ക്ലിനിക്കൽ പരീക്ഷണങ്ങൾ for pharmaceutical companies will lack motivation. This means that children will miss the opportunity to receive targeted treatments for cancer cells without damaging healthy cells with innovative therapies.

Professor Louis Chesler, who is leading the genetic testing research, said: “Children often don’t have equal access to the most advanced and potentially beneficial cancer treatments.” “The cost of developing gene-targeted drugs is very high. They tend to Test it on adults first so that more people can get treatment and the results can be seen faster. ”
“This test is an incredible advance because it will very clearly identify all genetic changes in the tumor.” “Gene testing gives clinicians an extremely powerful tool—helping them choose the right medicine for their children and do their best. It may be possible to quickly determine the effectiveness of these drugs. ”

Children’s tumors are usually genetically simpler than adult tumors, so eventually these drugs may be more effective in children.” The goal of ജനിതക പരിശോധന is to give scientists and doctors detailed genes for childhood tumors within a few weeks of diagnosis. information.

Genetic testing gives doctors strong evidence to use ടാർഗെറ്റുചെയ്‌ത ചികിത്സകൾ for younger patients, potentially preventing these patients from experiencing the side effects associated with traditional chemotherapy and radiation therapy.

Jack Daly, 14, from Wokingham, was diagnosed with a brain tumor when he was 7 and is now a brain tumor രക്ഷകൻ. Radiotherapy helped save his life, but left him with sequelae. “My athletic ability is not very good,” Jack said. “I have to get someone to help me dress and undress at school.” “My balance is not good-I am awkward and often fall. I worked hard at school, where I found friendship.” Jack and his mother, Helen, use their donations to make ends meet in Capels-hoping that ജനിതക പരിശോധന will make a huge difference in the quality of life of future children.

ജാക്ക് ക്യാൻസറിൽ നിന്ന് കരകയറിയതിനാൽ ആളുകൾ യഥാർത്ഥത്തിൽ പ്രശ്നം കാണുന്നില്ല. അയാൾക്ക് വീൽചെയറിൽ ഇരിക്കേണ്ട ആവശ്യമില്ല. അയാൾക്ക് തലപ്പാവു ധരിക്കേണ്ടതില്ല, ”ഹെലൻ പറഞ്ഞു.
“നിങ്ങൾ എപ്പോഴെങ്കിലും ജാക്കിനെ കണ്ടിട്ടുണ്ടെങ്കിൽ, അവൻ ഒരു സാധാരണ കൗമാരക്കാരനെപ്പോലെയാണ്. എന്നാൽ നിങ്ങൾ കാണാത്തത് ചികിത്സ മൂലമുണ്ടാകുന്ന മസ്തിഷ്ക ടിഷ്യു തകരാറാണ്. ”

ഈ ലേഖനത്തിന്റെ ഉറവിട URL: http://www.bbc.com/news/health-35918744