COG ACCL0431, Fennec Pharmaceuticals Inc., NCT00716976, Pedmark, SIOPEL 6, sodium thiosulfate (Pedmark

Sodium thiosulfate is approved by FDA to reduce the risk of ototoxicity associated with cisplatin in pediatric patients with localized, non-metastatic solid tumors

November 2022: In children aged one month and older with localised, non-metastatic solid tumours, the Food and Drug Administration has approved sodium thiosulfate (Pedmark, Fennec Pharmaceuticals Inc.) to lower the risk of ototoxi..

AstraZeneca UK Limited, durvalumab, Imfinzi, NCT03875235, TOPAZ-1

Durvalumab is approved for locally advanced or metastatic biliary tract cancer

November 2022: For adult patients with locally advanced or metastatic biliary tract cancer, the Food and Drug Administration has approved durvalumab (Imfinzi, AstraZeneca UK Limited) in combination with gemcitabine and cisplatin (..

Claudin 18.2, Claudins, hepatocellular carcinoma, renal cell carcinoma

Claudin 18.2 and its role in advanced gastric cancers

August 2022: The most apical portion of polarised epithelial and endothelial cells contains tight junctions, which are specialised membrane domains. The transmembrane proteins known as claudins, which are essential parts of tight..

ADVL0912, anaplastic lymphoma kinase, lymphoma, NCT00939770, Pfizer, Xalkori

Crizotinib is approved by FDA for ALK-positive inflammatory myofibroblastic tumor

 July 2022: Crizotinib (Xalkori, Pfizer Inc.) was granted approval by the Food and Drug Administration (FDA) for the treatment of adult and paediatric patients 1 year of age and older who were diagnosed with unresectable, recurr..

BRAF V600E, dabrafenib, Mekinist, melanoma, Novartis, Tafinlar, Trametinib

Dabrafenib in combination with trametinib is approved by FDA for unresectable or metastatic solid tumors with BRAF V600E mutation

July 2022: Dabrafenib (Tafinlar, Novartis) and trametinib (Mekinist, Novartis) received accelerated approval from the Food and Drug Administration for the treatment of adult and paediatric patients older than 6 years old with unre..

KEYTRUDA, Merck, Pembrolizumab, Roche Tissue Diagnostics, Ventana Medical Systems

Pembrolizumab is approved for advanced endometrial carcinoma

April 2022: Pembrolizumab (Keytruda, Merck) was approved by the Food and Drug Administration as a single agent for patients with advanced endometrial carcinoma that is microsatellite instability-high (MSI-H) or mismatch repair de..

BMS, CHECKMATE-816, nivolumab, NSCLC, Opdivo

Neoadjuvant nivolumab and platinum-doublet chemotherapy is approved for early-stage non-small cell lung cancer

March 2022: In the neoadjuvant setting, the FDA approved nivolumab (Opdivo, Bristol-Myers Squibb Company) in combination with platinum-doublet chemotherapy for adult patients with resectable non-small cell lung cancer (NSCLC).Thi..

China, Chongqing, Professor Qian Cheng, University of Pennsylvania

Patient in China achieves complete remission from leukemia after CAR T-Cell therapy

Feb 2022: In China, a patient whose life was on the verge of ending was entirely healed of leukaemia thanks to CAR T-cell therapy, which stimulated the immune system. All cancer cells vanished swiftly in the first study of its kin..

CAR - T Cell therapy, CAR T, CAR T Cell therapy in China, CAR T-Cell, China, Treatment in China

China-based CAR-T Cell therapy achieves breakthrough clinical trial results

June 2016: Professor Huang He of Zhejiang University's First Affiliated Hospital presented the outcomes of 10 clinical cases, including CAR-T cell therapy for leukaemia treatment, at the 2016 Haematogenic Immunity Summit in Hangz..

World Cancer Day 2022

4th Feb 2022: In India, cancer can have serious social and economic effects, typically resulting in family destitution and societal injustice. In this demographically young country, reported age-adjusted cancer incidence rates are..