According to a recent study published in JAMA Oncology, obesity is associated with an increased risk of early-onset colorectal cancer (CRC) in women.
Udokotela waseBoston Massachusetts General Hospital wenze ucwaningo lokunquma ukuthi kwenzekani komdlavuza we-colorectal kwabesifazane abangu-85,256 abangenawo umdlavuza kanye nesifo samathumbu esivuvukalayo ngokusekelwe kudatha yabesifazane abaneminyaka engu-25-42 ubudala.
Abacwaningi bathole izehlakalo eziyi-114 ze-CRC yokuqala (iminyaka emaphakathi ekuxilongweni, iminyaka engama-45) phakathi nesikhathi socwaningo. Kwabesifazane abakhuluphele ngokweqile (inkomba yesisindo somzimba [BMI] , 25-29.9 kg / m²) nabesifazane abakhuluphele (BMI, ≥30 kg/m²) abanesisindo esijwayelekile (BMI ingu-18.5-22.9 kg/m²) uma kuqhathaniswa nabesifazane, i-CRC yanda ubungozi. . Lokhu okutholakele kungahlotshaniswa ne-BMI eneminyaka engu-18 ubudala kanye nokukhuluphala ngemva kweminyaka engu-18 ubudala. Kuwo wonke amayunithi angu-5 e-BMI akhuphuka, i-RR (ingozi ehlobene) yomdlavuza we-colorectal ikhuphuka ngo-1.2. Uma kuqhathaniswa ne-BMI yeminyaka engu-18 ubudala yayingu-18.5-20.9 kg m² / owesifazane, i-BMI ingama-21 – 22.9 kg / m² abesifazane, i-CRC yokuqala ye-RRIs 1.32, i-BMI ingu-≥23kg i-RR yabesifazane yayingu-1.63. Ngokufanayo, uma kuqhathaniswa nabesifazane abathole ngaphansi kwe-5 kg noma belahlekelwa isisindo, abesifazane babe nokwanda kwe-20-39.9 kg ekuqaleni kwe-CRC ene-RR ye-1.65, abesifazane abanokwanda kwe-≥40 kg kanye ne-RR ye-2.15.
