Xyuston universitetidan Ruyven Chjan va Robert L. Boblitt oshqozon osti bezi saratoniga qarshi yangi dori ishlab chiqdilar. The research was published in the Journal of Cancer Research. The drug targets two genes at the same time, and this breakthrough achievement is of great significance for the treatment of aggressive and deadly pankreatik saraton.
Shuningdek, preparat saraton kasalligining boshqa turlarini yoki boshqa kasalliklarni davolash uchun dori vositalarini yaratish uchun asos bo'lib xizmat qilishi kutilmoqda. Oshqozon osti bezi saratoni me'da osti bezi hujayralari nazoratsiz ko'payib, parcha bo'lib rivojlana boshlaganda paydo bo'ladi va natijada paydo bo'lgan saraton hujayralari tananing boshqa qismlarini bosib olishi mumkin. Saratonning aksariyati oshqozon-ichak fermentlarini ishlab chiqaradigan oshqozon osti bezi hududidan boshlanadi. Belgilari bel yoki oshqozon og'rig'i, kutilmagan vazn yo'qotish va sariqlik (sariq teri). In addition, a person’s urine may appear dark yellow and itchy skin. There are two oncogenes associated with pancreatic cancer. There are two main ways for the drug to inhibit pancreatic cancer. They activate the nuclear factor of T cell 1 (NFAT1) and murine double microparticle 2 (MDM2), respectively. The latter gene regulates a shish suppressor gene called p53. When there is no tumor suppressor p53, MDM2 can cause cancer. NFAT1 is used to up-regulate the expression of MDM2, thereby promoting tumor growth. Factors related to diet, nutrition and the environment can lead to increased levels of these factors in the cell.
Doktor Jang ushbu kashfiyot haqida gapirganda, oshqozon osti bezi saratonini davolash uchun yangi, samarali va xavfsiz dorilarning klinik ehtiyojlari hali qondirilmaganligini aytdi. Bizning topilmalarimiz saraton kasalligini o'rganish bo'yicha katta yutuqlarni anglatadi. U qo'shimcha qildi: «Ko'pgina dorilar faqat bitta omilga qaratilgan. Biz saraton bilan bog'liq ikkita genga qaratilgan birikmani aniqladik. “Yangi dori MA242 ning sintetik birikmasidir. Preparat bir vaqtning o'zida ikkita oqsilni iste'mol qilishi va shu bilan o'smani yo'q qilish samaradorligini oshirishi mumkin.
