Main Topics

CAR T Cell Therapy for Solid Tumors
CAR T Cell Therapy for Solid Tumors

CAR T cell therapy has moved from its original effective blood cancers to solid tumors. Herein, a patient's modified T cells are made to express...

CAR T-Cell therapy for lymphoma
CAR T-Cell therapy for lymphoma

Introduction CAR T cell therapy has been a game-changer in the treatment of certain lymphomas, more so in patients relapsing or refractory to conventional therapies....

CAR T-Cell therapy for leukemia
CAR T-Cell therapy for leukemia

Introduction CAR T cell therapy is the breakthrough treatment against various kinds of leukemias, particularly B-cell ALL. In this treatment, genetically modified T cells are...

Types of cancer treated with CAR T-Cell therapy

Introduction CAR T cell therapy has really taken off in harnessing the immune system to specifically destroy cancerous cells. After showing tremendous success at first...

Mechanism of CAR T Cell therapy
Complete mechanism of CAR T Cell therapy explained

CAR T cell production involves several key steps. Initially, T cells are isolated from a patient's blood (autologous) or from a healthy donor (allogeneic). These...

Gamma delta T cells Latest option in cancer treatment
Gamma delta T cells: Latest option in cancer treatment

Two types of T-cells There exist two distinct categories of T cells: αβ T cells and γδ T cells. The previous statement describes a T-cell...

Targeting FGFR4 and CD276 with CAR T-cells demonstrates a strong antitumor impact against children rhabdomyosarcoma
Targeting FGFR4 and CD276 with CAR T-cells demonstrates a strong antitumor impact against children rhabdomyosarcoma

Chimeric antigen receptor (CAR) T-cells that specifically target Fibroblast Growth Factor Receptor 4 (FGFR4), a surface tyrosine receptor that is extensively expressed in rhabdomyosarcoma (RMS),...

Disruption of CD5 on CAR T Cells Enhances the Effectiveness of Anti-Tumor Treatment
Disruption of CD5 on CAR T Cells Enhances the Effectiveness of Anti-Tumor Treatment

CAR T-Cell therapy in the treatment of cancer A preclinical study conducted by researchers at the University of Pennsylvania’s Perelman School of Medicine and Abramson...

The future of gene therapy What to expect in the next decade
The future of gene therapy: What to expect in the next decade?

Gene therapy Gene therapy, which means changing genes to cure or avert diseases, has progressed significantly in the last number of years. The future of...

The future of gene therapy for genetic disorders
Unlocking the genetic code: The future of gene therapy for genetic disorders

Gene therapy has typified the revolution in medicine that gives hope to various genetic disorders. This advanced treatment stops, and sometimes even reverses, the progress...

CRISPR and gene editing Revolutionizing gene therapy pic
CRISPR and gene editing: Revolutionizing gene therapy

This makes the CRISPR-Cas9 technology one of the most potent tools known in gene therapy for very accurate, efficient, and versatile genome editing; it has...

Gene therapy in treating cancer Success stories and challenges
Gene therapy in treating cancer: Success stories and challenges

Gene therapy is shifting concepts in cancer treatments from genes to boosting immune responses. The success stories are CAR-T cell therapies like Kymriah against leukaemia,...

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