New treatment identified for low grade and serous ovarian cancer

Share This Post

May 2022: Trametinib may become a new standard of care for recurring, low-grade serous ovarian cancer (Mekinist). According to study findings published in the February 2022 issue of The Lancet, trametinib beat both chemotherapy and anti-estrogens like tamoxifen by around 52 percent, adding six months of progression-free (period during which the cancer did not advance) survival for patients.


New treatment for ovarian cancer


In 260 women with recurrent serous ovarian tumours who had previously received chemotherapy, researchers from the United States and the United Kingdom compared once-daily oral trametinib to one of five standard of care regimens (either chemotherapy or anti-estrogen medications). When compared to usual treatment, trametinib participants showed a fourfold higher response to therapy after 15 months. Trametinib outperformed all other treatments, slowing disease progression for 13 months (versus seven months for standard treatment). Skin rash, anaemia, high blood pressure, diarrhoea, and weariness are some of the potentially dangerous adverse effects of trametinib treatment.

Low-grade serous ovarian cancer is a difficult-to-treat invasive form of ovarian cancer marked by strong hormone receptor activation, genetic alterations, and poor chemotherapy response. Until now, the cancer toolbox lacked effective therapeutic options for patients with low-grade serous ovarian cancer. According to an editorial accompanying the report, 70% of these women will recur, with only 5% responding to further chemotherapy.


Subscribe To Our Newsletter

Get updates and never miss a blog from Cancerfax

More To Explore

Ivosidenib is approved by FDA for myelodysplastic syndromes

Ivosidenib is approved by FDA for myelodysplastic syndromes

The Food and Drug Administration approved ivosidenib (Tibsovo, Servier Pharmaceuticals LLC) for adult patients with relapsed or refractory myelodysplastic syndromes (MDS) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation, as detected by an FDA-approved test.

Need help? Our team is ready to assist you.

We wish a speedy recovery of your dear and near one.

درمان سرطان در تركيه
Start chat
Need help with cancer treatment?
Scan the code
Welcome to CancerFax !

CancerFax is the most trusted international patient facilitator working with top cancer hospital's in the world like MD Anderson, Dana Farber, Asan, NCC Japan, Sheba, Beijing Cancer Institute and Apollo to bring you best of therapies and drugs.

Let us know what services would you like to avail?

1) Cancer treatment in the USA, Japan, Israel, India, Korea or Singapore?
2) CAR T-Cell therapy treatment
3) Cancer vaccine
4) Online video consultation
5) Proton therapy