New methods for early screening of liver cancer, combined with statin therapy can improve efficacy

Share This Post

The advantages of early detection in cancer screening cannot be underestimated. There is a lot of evidence that the importance of rapid intervention can not only prevent the spread of the disease, but also significantly improve the survival rate of almost all forms of cancer. However, identifying early markers of cancer remains a challenge for scientists. Although now, researchers from Brunel University and Leeds University in London have just released new evidence that can provide hope for early identification of liver cancer.

The results of the study show that the expression of glycolytic enzymes in the liver of pre-cancerous cirrhosis is significantly increased, which is related to the significantly increased risk of developing hepatocellular carcinoma (HCC), and can identify groups at risk of malignant HCC. The results of this new study were published in the “Forefront of Cellular and Developmental Biology” with the title “The high expression of glycolytic genes in liver cirrhosis is associated with the risk of developing liver cancer.

In other words: the conversion of glycolysis occurs in the precancerous period, the expression level of glycolysis-related genes is positively correlated with the progression of liver cirrhosis to HCC, and the prognosis of patients with biopsy HCC is poor. This indicates that the expression of glycolytic enzymes can be used as a new biomarker to predict the risk of HCC in patients with liver cirrhosis in the later stage. Further research is needed to determine whether these changes in gene expression are confirmed as changes in glycolysis activity.

The results of the study reveal promising methods for improving the survival of HCC through early detection and treatment. According to Dr. Papa, the shift in glycolysis expression profile in cirrhotic cells may even become the target of new HCC therapies. For example, clinical trials are currently underway to explore the role of statins-used to help prevent cardiovascular disease, HCC development in patients with liver cirrhosis or recurrence of HCC after surgical resection, most likely by blocking cholesterol synthesis, statins inhibit Glycolysis.

Early Liver Cancer Detection through Glycolytic Genes

Subscribe To Our Newsletter

Get updates and never miss a blog from Cancerfax

More To Explore

Limkato Korea’s first CAR T Cell therapy
CAR T-Cell therapy

Limkato: Korea’s first CAR T Cell therapy

South Korea is making significant strides in **CAR T cell therapy**, highlighted by the approval of **Limkato**, the first domestically developed CAR T therapy by **Curocell** in 2023. This milestone reduces reliance on foreign treatments and boosts Korea’s position in the global biotech industry. With strong government support and cutting-edge research, Korea is poised to advance CAR T therapies further, expanding applications and improving accessibility for cancer patients.

TIL therapy for melanoma in China
Melanoma

TIL therapy for melanoma in China

Tumor-Infiltrating Lymphocyte (TIL) therapy represents a promising advancement in the treatment of melanoma, particularly in cases where traditional treatments have failed. In China, the adoption of TIL therapy is gaining momentum, offering new hope to patients battling this aggressive form of skin cancer.

Need help? Our team is ready to assist you.

We wish a speedy recovery of your dear and near one.

Start chat
We Are Online! Chat With Us!
Scan the code
Hello,

CancerFax is the most trusted online platform dedicated to connecting individuals facing advanced-stage cancer with groundbreaking cell therapies.

Send your medical reports and get a free analysis.

🌟 Join us in the fight against cancer! 🌟

Привет,

CancerFax — это самая надежная онлайн-платформа, призванная предоставить людям, столкнувшимся с раком на поздних стадиях, доступ к революционным клеточным методам лечения.

Отправьте свои медицинские заключения и получите бесплатный анализ.

🌟 Присоединяйтесь к нам в борьбе с раком! 🌟