New methods for early screening of liver cancer, combined with statin therapy can improve efficacy

Share This Post

The advantages of early detection in cancer screening cannot be underestimated. There is a lot of evidence that the importance of rapid intervention can not only prevent the spread of the disease, but also significantly improve the survival rate of almost all forms of cancer. However, identifying early markers of cancer remains a challenge for scientists. Although now, researchers from Brunel University and Leeds University in London have just released new evidence that can provide hope for early identification of liver cancer.

The results of the study show that the expression of glycolytic enzymes in the liver of pre-cancerous cirrhosis is significantly increased, which is related to the significantly increased risk of developing hepatocellular carcinoma (HCC), and can identify groups at risk of malignant HCC. The results of this new study were published in the “Forefront of Cellular and Developmental Biology” with the title “The high expression of glycolytic genes in liver cirrhosis is associated with the risk of developing liver cancer.

In other words: the conversion of glycolysis occurs in the precancerous period, the expression level of glycolysis-related genes is positively correlated with the progression of liver cirrhosis to HCC, and the prognosis of patients with biopsy HCC is poor. This indicates that the expression of glycolytic enzymes can be used as a new biomarker to predict the risk of HCC in patients with liver cirrhosis in the later stage. Further research is needed to determine whether these changes in gene expression are confirmed as changes in glycolysis activity.

The results of the study reveal promising methods for improving the survival of HCC through early detection and treatment. According to Dr. Papa, the shift in glycolysis expression profile in cirrhotic cells may even become the target of new HCC therapies. For example, clinical trials are currently underway to explore the role of statins-used to help prevent cardiovascular disease, HCC development in patients with liver cirrhosis or recurrence of HCC after surgical resection, most likely by blocking cholesterol synthesis, statins inhibit Glycolysis.

Early Liver Cancer Detection through Glycolytic Genes

Subscribe To Our Newsletter

Get updates and never miss a blog from Cancerfax

More To Explore

Seattle Children's Hospital to Start CAR T-Cell Clinical Trial for Pediatric Lupus Patients
CAR T-Cell therapy

Seattle Children’s Hospital to Start CAR T-Cell Clinical Trial for Pediatric Lupus Patients

Seattle Children’s Hospital is launching a groundbreaking CAR T-cell clinical trial for pediatric lupus patients. This innovative approach harnesses the body’s immune cells to target and eliminate lupus-affected cells, offering new hope for young patients with this autoimmune disorder. The trial represents a significant advancement in lupus treatment, aiming to improve outcomes and reduce long-term complications for children suffering from this challenging condition.

Efficacy of CAR T Cell Therapy in B-Cell lymphoma Richter Transformation
CAR T-Cell therapy

Efficacy of CAR T Cell Therapy in B-Cell lymphoma Richter Transformation

CAR T cell therapy has shown promising efficacy in treating B-cell lymphoma Richter Transformation, a rare and aggressive disease. This advanced therapy involves genetically modifying a patient’s T cells to target and destroy cancerous B cells. Clinical trials indicate significant response rates, with some patients achieving complete remission. Despite challenges like potential severe side effects, CAR T cell therapy represents a groundbreaking approach, offering hope for improved outcomes in this difficult-to-treat condition.

Need help? Our team is ready to assist you.

We wish a speedy recovery of your dear and near one.

Start chat
We Are Online! Chat With Us!
Scan the code
Hello,

Welcome to CancerFax !

CancerFax is a pioneering platform dedicated to connecting individuals facing advanced-stage cancer with groundbreaking cell therapies like CAR T-Cell therapy, TIL therapy, and clinical trials worldwide.

Let us know what we can do for you.

1) Cancer treatment abroad?
2) CAR T-Cell therapy
3) Cancer vaccine
4) Online video consultation
5) Proton therapy