New adjuvant therapy for pancreatic cancer comes out

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In a recent interview, Dr. Afsaneh Barzi, assistant professor of clinical medicine at the University of Southern California Norris Comprehensive Cancer Center, told you about existing and emerging new adjuvant therapies for patients with non-metastatic pancreatic cancer.

Gemcitabine is given to patients with pancreatic cancer as a standard practice to assess response. However, Barzi said that the patient’s response to gemcitabine was very poor and that many patients were unable to undergo surgery. The LAPACT trial investigated the combination therapy of gemcitabine and nab-paclitaxel (Abraxane). Tests show that 36% of pancreatic cancer patients respond to treatment, and about 15% of pancreatic cancer patients can receive surgical treatment.

In addition, a meta-analysis of the FOLFIRINOX study of patients with locally advanced pancreatic cancer showed that approximately 28% of pancreatic cancer patients were able to undergo surgery. Barzi explained that as chemotherapy becomes more effective, the likelihood of resection increases. Therefore, the patient’s resection should be evaluated accordingly. Barzi concluded that although most patients may still not be eligible for surgery, it is still worth evaluating patients to find patients who can undergo surgery after neoadjuvant therapy.

https://www.onclive.com/conference-coverage/soss-gi-usc-2018/dr-barzi-on-available-and-emerging-neoadjuvant-approaches-in-pancreatic-cancer

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Susan Hau is a distinguished researcher in the field of cancer cell therapy, with a particular focus on T cell-based approaches and cancer vaccines. Her work spans several innovative treatment modalities, including CAR T-cell therapy, TIL (Tumor-Infiltrating Lymphocyte) therapy, and NK (Natural Killer) cell therapy.

Hau's expertise lies in cancer cell biology, where she has made significant contributions to understanding the complex interactions between immune cells and tumors.

Her research aims to enhance the efficacy of immunotherapies by manipulating the tumor microenvironment and exploring novel ways to activate and direct immune responses against cancer cells.

Throughout her career, Hau has collaborated with leading professors and researchers in the field of cancer treatment, both in the United States and China.

These international experiences have broadened her perspective and contributed to her innovative approach to cancer therapy development.

Hau's work is particularly focused on addressing the challenges of treating advanced and metastatic cancers. She has been involved in clinical trials evaluating the safety and efficacy of various immunotherapy approaches, including the promising Gamma Delta T cell therapy.

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