Olunye ucwaningo lubonisa ukuthi ukudla amagilebhisi kungase kuvimbele umdlavuza. Ukonakala kwamaphaphu kuwuhlobo lwesimila esibulala kakhulu emhlabeni, futhi u-80% wokufa uhlobene nokubhema. Naphezu kokulawula ugwayi, amasu aphoqelelayo okuvimbela i-chemoprevention ayadingeka ngale ndlela. Iqembu labacwaningi abavela e- University of Geneva (I-UNIGE), eSwitzerland, yahlola into evamile evamile, i-resveratrol, etholakala emagilebhisini nasewayinini elibomvu. Ngenkathi izakhiwo zayo zokuvimbela i-chemopreventive ngokumelene nokukhula okuthonya ipheshana elihlobene nesisu zigcinwe kungobo yomlando ukuhlolwa kwangaphambilini, i-resveratrol kuze kube manje ayizange ibonise umthelela emazingeni amaphaphu. Ngenxa yokuhleleka kwamakhala, i I-UNIGE Iqembu lathola imiphumela ekhuthazayo ngokuhlukile kuphenyo oluqondiswe kumagundane futhi lakhonjiswa kwidayari Imibiko Yesayensi
Kunoma yikuphi, i-resveratrol ayibonakali inengqondo ekuvimbeleni ukonakala kwamaphaphu: lapho idliwe, isetshenziswa futhi ibulawe kungakapheli imizuzu, futhi ngale ndlela, ayinawo amandla anele okufinyelela emaphashini. “Lesi yisizathu sokuhlola kwethu ukuthola indlela i-resveratrol engancibilika ngayo ngamanani abanzi, naphezu kweqiniso lokuthi ayincibiliki ngokwanele emanzini, ngomgomo othile wokugcina wokuvumela inhlangano yamakhala. Lolu hlelo, olufanele abantu, lenza inhlanganisela ikwazi ukufeza amaphaphu,” kucacisa u-Aymeric Monteillier, umcwaningi eSikoleni Sesayensi Yezemithi se-UNIGE Faculty of Science, kanye nomdali oyinhloko wokuhlolwa. Ukulungiswa kwe-resveratrol okutholwe emaphashini ngemva kokuhlelwa kwekhala kwencazelo kwakuphakeme izikhathi ezingu-22 kunalapho kuthathwa ngomlomo. Ithuluzi le-chemoprevention cishe likhonjwa nge-apoptosis, inqubo lapho amaseli azihlela khona ukuwa kwawo futhi lapho amaseli wesimila aphuma khona. Iqembu lophenyo le-UNIGE manje selizogxila ekutholeni i-biomarker engangeza ekunqumeni kwabantu abafanelekela ukwelashwa kokuvimbela nge-resveratrol.
I-Resveratrol i-molecule eyaziwayo etholakala ezithasiselweni zokudla, okusho ukuthi akukho okunye ukuhlolwa okunobuthi okungadingeka ngaphambi kokuthengiswa njengendlela yokwelapha yokuvimbela. “Lokhu kuvezwa wumdlandla omangazayo wezezimali emibuthanweni yezemithi. Izinhlayiya ngokungangabazeki ziyisisekelo futhi azinalungelo lobunikazi, futhi ukugwema isimila kucabanga ngokudinga ukulandelelwa phakathi neminyaka eminingi,” kuzikhalela uMuriel Cuendet, ngaphandle kokuvimbela ukuthuthukiswa kokwelashwa kokuvimbela kubantu.
