O'pka saratoni, oshqozon saratoni, ichak saratoni va ko'krak saratoni fizik tekshiruv orqali nisbatan oson tekshirilishini hamma biladi, shuning uchun erta tashxis qo'yilgan saraton bemorlari yaxshi prognozga ega va ularning yashash muddati ancha uzaytiriladi.
However, liver cancer, another serious life-threatening cancer that accounts for more than 55% of the world’s cancers in China, is difficult to be diagnosed early. Most patients are diagnosed late and lose the chance of surgery. Although other treatments are diverse, it is difficult to maintain long-term survival. The early diagnosis of jigar saratoni has always been a difficult problem in the tumor world.
Bu safar xitoylik olimlarning muvaffaqiyati, ayniqsa, faxrimizga arziydi!
12 mart kuni Amerika Fanlar Akademiyasi (PNAS) ma'lumotlari Milliy saraton markazi, Xitoy Tibbiyot fanlari akademiyasining saraton kasalxonasi va Pekin Panshengzi Gen Technology Co tomonidan to'ldirilgan hujayrasiz DNK (cfDNK) va oqsil belgilarini chiqardi. ., Ltd. HBV tashuvchilarning istiqbolli guruhida jigar saratoni uchun erta skrining natijalari.
Tadqiqotda xitoylik olimlar tomonidan mustaqil ravishda ishlab chiqilgan protein markerlari bilan birlashtirilgan cfDNK gen mutatsiyasining suyuq biopsiya usuli - HCCscreen ishlatilgan. Qattiq klinik tekshiruvdan so'ng, tadqiqot natijalari jigar saratonini erta tekshirish uchun ishlatilishi kutilmoqda.
Ushbu tadqiqotda 3 sm dan kam bo'lgan erta jigar saratoni aniqlanishi mumkin. Tadqiqotchilar hujayrasiz DNK mutatsiyalari va oqsil markerlarining periferik qon namunalarini oldilar va normal alfa-fetoprotein va B-ultratovush natijalariga ega 331 HBV tashuvchisini tekshirdilar.
Natijalar 24 ta holat (ehtimol jigar saratoni bilan) aniqlandi va 6-8 oylik kuzatuvda 4 ta holatda jigar saratoni aniqlandi. Qolgan 307 bemor salbiy edi va kuzatuv davrida jigar saratoni aniqlanmadi. 100% sezgirlik, 94% o'ziga xoslik va 17% ijobiy bashoratli qiymatga erishing.
Early-stage liver cancer can be detected by blood testing from asymptomatic HBV carriers. This technology can achieve accurate detection of common mutations in liver cancer such as cfDNA point mutations, insertion deletion mutations, and HBV virus integration. At present, the research method has been further optimized, the sensitivity is stable at more than 93%, and the specificity can be increased to more than 98%.
Biroq, hozirgi vaqtda ushbu texnologiya hali tadqiqot bosqichida va jigar saratonini erta tekshirish uchun klinik skrining uchun rasman tasdiqlanmagan. Shu bilan birga, yuqori xavfli yoki saratonni erta skriningga muhtoj bo'lgan odamlar saratonni erta tekshirish uchun tibbiy ko'rikdan o'tish uchun oddiy shifoxona yoki tibbiy ko'rik muassasasiga borishni tanlashlari mumkin!
Hozirgi vaqtda Xitoyda ko'p odamlar Yaponiyada sayohat qilishni va xarid qilishni yaxshi ko'radilar. Darvoqe, har xil saraton kasalliklarini erta skriningdan o‘tkazishni o‘z ichiga olgan keng qamrovli tibbiy ko‘rikdan o‘ting va sog‘lom tanani ta’minlash uchun o‘yin davomida o‘zingizga xotirjamlik bering.
