In previous studies, researchers have clarified how taking aspirin can help prevent bowel cancer. This study found that analgesics block key processes related to tumor formation. As we all know, regular aspirin can reduce the risk of colon cancer, but the anti-tumor properties of this drug are not fully understood.
Researchers at the University of Edinburgh are concerned with a structure called nucleolus found in cells. The activation of nucleoli causes shish formation, and dysfunction is also associated with Alzheimer’s disease and Parkinson’s disease. A team from the University of Edinburgh Cancer Research Centre in the United Kingdom tested the effect of aspirin on laboratory-grown cells and tumor biopsies in patients with colon cancer.
Ular aspirinning yadro funktsiyasi uchun asosiy molekula bo'lgan TIF-IA deb nomlangan asosiy molekulani to'sib qo'yishini aniqladilar.
Yo'g'on ichak saratoni bilan kasallangan bemorlarning hammasi ham aspiringa ta'sir o'tkazmaydilar, ammo tadqiqotchilar ularning topilmalari qaysi biri ko'proq foyda keltirishi mumkinligini aniqlashga yordam berishi mumkinligini aytishadi.
Aspirin ba'zi bir qon tomir turlarini keltirib chiqaradigan ichki qon ketishni o'z ichiga olgan nojo'ya ta'sirlarga ega va uzoq muddat foydalanish tavsiya etilmaydi. Tadqiqotchilarning ta'kidlashicha, tadqiqot aspirin ta'sirini taqlid qiluvchi yangi, xavfsizroq davolash usullarini ishlab chiqishga imkon beradi. Tadqiqot Nucleic Acid Research jurnalida chop etilgan va Tibbiy tadqiqotlar kengashi, Biotexnologiya va Biologiya fanlari tadqiqot kengashi tomonidan moliyalashtirilgan. Dunyo bo'ylab saraton tadqiqotlari, ichak va saraton tadqiqotlari va Rose Tree Trust ham ushbu ishni qo'llab-quvvatlaydi.
Buyuk Britaniyaning Edinburg shahridagi saraton kasalligini o'rganish markazining tadqiqotchilari: "Biz ushbu topilmalardan juda xursandmiz, chunki ular ko'plab kasalliklarning oldini olish uchun aspirin mexanizmini taklif qilishdi. Aspirinning TIF-IA va nukleolyar faollikni qanday oldini olishini yaxshiroq tushunib, yangi davolash usullari va maqsadli davolash usullarini ishlab chiqishga katta umid beradi. "
