برطانوی سائنسدانوں نے بچپن کے ٹیومر کی جینیاتی جانچ شروع کردی۔ برطانوی سائنسدانوں کو امید ہے کہ جینیاتی جانچ سے کم عمر مریضوں کو نئے اور ذاتی نوعیت کے علاج ملیں گے جس سے ان کی بقا میں اضافہ ہوگا۔ نئے ٹیسٹ میں کینسر کی 81 مختلف جینیاتی تبدیلیوں کا تجزیہ کیا گیا ہے۔
Scientists say the test will lead to “a higher level of playing field” and accelerate children’s access to important new drug treatments. The test was performed at the Royal Marsden National Health System Hospital in London and will be tested on 400 children from all over the UK over the next two years.
The test has been implemented with genetic funding from the National Institutes of Health (NIHR) foundation and the کینسر Institute. A charity called Christopher has provided more than £ 300,000 in funding to develop the test. The organization was founded by a couple whose children died of invasive دماغ کے ٹیومر at the age of six.
This is a real first step towards personalized کینسر کے علاج for children,” said Christopher’s parents, Karen and Kevin Capel. Christopher got a generic ٹیومر. Hopefully, in the future, children will know exactly what type of tumor they have.” “We almost feel that the treatment for the child is not to kill the cancer, but to kill our child.”
“He used to be a healthy, happy, very athletic 4-year-old kid. But he became unable to speak or even eat on his own, and lost weight. “In the year he was diagnosed, he was unable to grow into a child of his age. We tried to keep him from other children.”
بچوں میں مہلک ٹیومر بہت کم ہوتے ہیں، مریضوں کی تعداد زیادہ نہیں ہوتی، اور طبی ٹیسٹ for pharmaceutical companies will lack motivation. This means that children will miss the opportunity to receive targeted treatments for cancer cells without damaging healthy cells with innovative therapies.
Professor Louis Chesler, who is leading the genetic testing research, said: “Children often don’t have equal access to the most advanced and potentially beneficial cancer treatments.” “The cost of developing gene-targeted drugs is very high. They tend to Test it on adults first so that more people can get treatment and the results can be seen faster. ”
"یہ ٹیسٹ ناقابل یقین پیش قدمی ہے کیونکہ اس سے ٹیومر میں ہونے والی تمام جینیاتی تبدیلیوں کی واضح طور پر نشاندہی ہوگی۔" "جین کی جانچ معالجین کو ایک انتہائی طاقتور ٹول فراہم کرتی ہے — جس میں وہ اپنے بچوں کے لئے صحیح دوا کا انتخاب کرتے ہیں اور ان کی پوری کوشش کرتے ہیں۔ ممکن ہے کہ ان دوائیوں کی تاثیر کا فوری تعین کرنا ممکن ہو۔ "
Children’s tumors are usually genetically simpler than adult tumors, so eventually these drugs may be more effective in children.” The goal of جینیاتی جانچ is to give scientists and doctors detailed genes for childhood tumors within a few weeks of diagnosis. information.
Genetic testing gives doctors strong evidence to use ھدف بنائے گئے علاج for younger patients, potentially preventing these patients from experiencing the side effects associated with traditional chemotherapy and radiation therapy.
Jack Daly, 14, from Wokingham, was diagnosed with a brain tumor when he was 7 and is now a brain tumor زندہ بچنے والے. Radiotherapy helped save his life, but left him with sequelae. “My athletic ability is not very good,” Jack said. “I have to get someone to help me dress and undress at school.” “My balance is not good-I am awkward and often fall. I worked hard at school, where I found friendship.” Jack and his mother, Helen, use their donations to make ends meet in Capels-hoping that جینیاتی جانچ will make a huge difference in the quality of life of future children.
"لوگ واقعی اس مسئلے کو نہیں دیکھتے کیونکہ جیک کینسر سے صحت یاب ہوگیا ہے۔ اسے ویل چیئر میں رہنے کی ضرورت نہیں ہے۔ ہیلن نے کہا کہ اسے پٹی نہیں پہننی ہوگی۔
"اگر آپ نے جیک کو کبھی دیکھا ہے تو ، وہ ایک عام نوعمر لڑکے کی طرح لگتا ہے۔ لیکن جو آپ نہیں دیکھتے وہ علاج کی وجہ سے دماغی ٹشو کو پہنچنے والا نقصان ہے۔
اس مضمون کا ماخذ URL: http://www.bbc.com/news/health-35918744
