2021 Juli: Beta-thalassemia mangrupikeun kaayaan turunan anu disababkeun ku mutasi gén anu aub dina produksi komponén hémoglobin, protéin anu ngangkut oksigén ka sakumna awak. Mutasi ieu ngalarang atanapi ngawatesan formasi hémoglobin, nyababkeun kakurangan sél getih beureum dewasa sareng anémia anu terus-terusan, ogé kaleuwihan beusi.
Mutasi anu ngabalukarkeun talasemia béta mangaruhan kira-kira 80-90 juta jalma di sakuliah dunya, atawa kira-kira 1.5 persén populasi.
Children frequently inherit the gene mutation from parents who are carriers but show no signs of the condition. The child has a 25% probability of acquiring beta-thalassemia and a 50% chance of being an asymptomatic carrier like their parents in this circumstance.
Many individuals with beta-thalassemia need regular blood transfusions for the rest of their lives (transfusion-dependent thalassemia), which can cause a variety of health problems, including iron excess, which can harm the heart, liver, and endocrine system.
Anu sanésna henteu meryogikeun transfusi rutin pikeun salamet (henteu gumantung kana transfusi), tapi aranjeunna ogé kaserang trombosis, hipertensi pulmonal, gagal ginjal, sareng borok suku, diantara masalah kaséhatan anu sanés.
Talasemia Béta nyebarkeun langkung gancang tibatan kantos
People from the Mediterranean, the Middle East, North Africa, India, and Central and Southeast Asia have been reported to have the highest prevalence of talasemia béta. As a result of the rise in modern migration, instances are increasingly sprouting up in more places.
Nagara-nagara di Laut Tengah anu ngagedéan sumberdaya pikeun ngatasi permintaan anu tumuh pikeun pasién béta-talasemia. Sedengkeun ahli kaséhatan sareng politikus di Éropa Kalér sareng Kulon ngakuan trend ieu, aranjeunna kakurangan data anu padet ngeunaan kajadian sareng pola panyakit. Hésé ngadamel kasus pikeun investasi dina inisiatif pikeun méréskeun masalah tanpa data, sahingga langkung hésé pikeun pasién pikeun ngaidentipikasi panyadia anu leres.
Béta-talasemia & COVID-19
Perlakuan béta-talasemia meryogikeun sajumlah ageung élmu sareng sumber, kalebet sumbangan getih anu aman. Pandemi COVID-19 ngagaduhan pangaruh penting kana suplai getih global, hasilna turunna sumbangan getih di kaseueuran nagara-nagara Uni Éropa sareng masalah unik di nagara-nagara berkembang sareng berpenghasilan rendah kalayan sumber daya terbatas sareng konsentrasi tinggi pasien panyawat. Nyingkahan donor sareng kapasitas terbatas di situs sumbangan, ogé pangolahan getih sareng gangguan ranté suplai, sadayana nyumbang kana turunna sumbangan getih.
Rézim pangobatan anu énggal pikeun béta-talasemia
The only solution for beta-thalassemia now available is a stem cell transplant, although many individuals may not be eligible. Only around 10% of patients who are eligible for a stem cell transplant actually get one, owing to exorbitant expenses or a lack of a donor. Another long-term strategy is prevention through carrier screening and education, which has proven to be effective in several countries.
Nanging, kamajuan anu anyar dina bentang perawatan parantos nyayogikeun pilihan anu diperyogikeun pikeun ngungkulan anémia anu disababkeun ku béta-talasemia sareng ngamungkinkeun pasién janten kirang ngandelkeun transfusi sél getih beureum.
