Ndichiri kushanda pagadziriro yokudzivirira zvirwere, ndakangoerekana ndawana rudzi rutsva rwesero rinouraya kenza yakawanda. Kubudirira kutsva uku kunogona kuve mubatsiri mukuru kune varwere vegomarara, sezvo ichangobva kuwanikwa t-cell inouraya akawanda marudzi ekenza maseru. Nekudaro, izvi zvakaganhurirwa kumarabhoritari kusvika zvino, uye kutsvagisa kwenguva refu kunodiwa kugadzira mushonga wakazara.
Masayendisiti ekuBritain anobva kuCardiff Medical University akawana netsaona rudzi rwesero (iyo t-cell) inoparadza marudzi mazhinji egomarara. Sekureva kweTelegraph iyi inogona kuve yakakura budiriro kuwanikwa mukuvhima kwekurapa gomarara kune ese marudzi egomarara. Chiremba, achiongorora masero machena eropa mubhangi reropa, akawana rudzi rutsva rwe t-sero inotakura nyowani-isati yamboonekwa receptor inoita kunge hoko inobata, inonamatira kune vanhu vazhinji kenza, uku ichifuratira masero ane hutano, Iyo Telegraph inoshuma. Mumamiriro emurabhoritari, masero ekudzivirira emuviri akashongedzerwa neanogamuchira mutsva, akakwanisa kuuraya masero egomarara kubva munhengo dzakawanda, kusanganisira mapapu, ropa, mapfupa, uye itsvo.
Sekureva kwaPurofesa Andrew Sewell, mukuru wechidzidzo, uye nyanzvi yemhando yesero pa Cardiff Medical University, kuwanikwa uku kunogona kushandiswa kugadzira mushonga wepasi rose wemagomarara mazhinji.
Cancer inodaro mamiriyoni 10 anogara gore rimwe nerimwe munyika, uye mugove weIndia une zvishoma 8% izvo. Huwandu uhu hunotyisa uye huri kuwedzera gore rega rega nenzira itsva uye matekinoroji ekukurumidza kuongororwa kwegomarara.
Iyo data yeWHO inoratidza kuti India ine nyaya nyowani dzinosvika miriyoni imwe chete gore rega rega, uye zvinopfuura makumi mashanu muzana ezviitiko izvi zvichaonekwa muvakadzi. Kansa yepabonde yakwira nezvikamu zvinodarika makumi matatu nepfumbamwe kubva muzana pakati pa39 na1990 uye ndiro gomarara rinonyanyozivikanwa pakati pevakadzi. Chirevo cheLancet chinoenderera mberi chichiwedzera kuti pakati pa2016 na1990, nhamba yevakafa negomarara muIndia yakawedzera ne2016 muzana. Panguva imwe cheteyo, nhamba dzekenza dzegomarara dzakawedzerawo nechikamu che112%. Gwaro iri rinoratidzawo kuti muna 48.7, munyika maive nevarwere vegomarara remapapu vanosvika zviuru makumi matanhatu nezvinomwe, makumi manomwe nemazana maviri kubva muzana vaive varume, uye gomarara rechiropa yakawedzerawo nezvikamu makumi matatu nezviviri kubva muzana kubva muzana kubva muna 32.2, nezviitiko zviuru makumi matatu zvakashumwa muna 1990.
Kuwanikwa kutsva pakurapa kenza
Pamhando ipi neipi yehutachiona, immune system yemuviri inotanga kushanda uye inoita sechidziviriro chemusikirwo pachiri. Zvisinei, inorwisawo masero egomarara. Masayendisiti epaCardiff Medical University, Britain, aitsvaga nzira dzisina kujairika uye dzisina kuwanikwa nzira dzinorwisa zvirwere zvinorwisa mamota. Zvakaonekwa kuti kune t-cell inorwisa nekuuraya marudzi mazhinji emakenza.
Iyi t-cell inoshanda sei kurapa cancer?
Chikwata cheCardiff Medical University, Britain, chakawana T-sero uye receptor yayo inogona kuwana nekuuraya akasiyana siyana maseru ane cancer murabhoritari, anosanganisira kenza yemapapu, kenza yeganda, kenza yeropa, colon cancer, kenza yemazamu, gomarara repfupa, kenza yeprostate, kenza yechibereko, kenza yeitsvo, uye masero egomarara remuchibereko. Chaizvoizvo kuti izvi zvinoitika sei zvichiri kuda kuongororwa uye masayendisiti ari kushanda pazviri.
Iyi chaiyo T-cell receptor inopindirana nemamolekemu inonzi MR1, iri pamusoro pechiso chega chega mumuviri wemunhu.
Unogona kuda kuverenga: Mota T-cell kurapwa muIndia
Zvinofungidzirwa kuti MR1 iri mureza yakakanganiswa metabolism inoenderera mukati mesero regomarara kune immune system.
"Isu ndisu vekutanga kutsanangura T-sero rinowana MR1 mumasero egomarara - izvo zvisati zvamboitwa, iyi ndiyo yekutanga yerudzi rwayo," mumwe muongorori Garry Dolton akaudza BBC.
Ndezvipi zvimwe zvinotaurwa necancer nezvekuwanikwa kwekenza?
Lucia Mori naGennaro De Libero, vanobva kuYunivhesiti yeBasel muSwitzerland, vakati tsvagiridzo iyi yaive ne "kugona kukuru" asi yaive pachinhanho chekutanga kuti ichazoshanda mukenza dzese.
"Tiri kufara kwazvo pamusoro pemabasa ekuzvidzivirira muviri kweiyo itsva T-cell huwandu uye nekugona kushandiswa kweTCRs kwavo mune tumor cell therapy," vakadaro.
Daniel Davis, purofesa wezvekudzivirira muviri paUniversity yeManchester, akati: "Panguva ino, uku kutsvagisa kwekutanga uye kwete padyo nemishonga chaiyo yevarwere.
"Hapana mubvunzo kuti chinhu chinonakidza kuwana, kusimudzira ruzivo rwedu rwekutanga nezve immune system uye mukana wemishonga mitsva munguva yemberi."
Unogona kuda kuverenga: CAR T Cell kurapa muChina
