The latest research found that some statins can improve the efficacy of chemotherapy drugs used to treat blood cancer in mouse models. Statins are drugs that treat patients with reduced fat in the blood. They are commonly used to lower triglyceride and cholesterol levels and reduce fat associated with heart attacks and strokes. In this new experiment, the researchers found that they may also be used to treat certain blood cancers.
Panaliti saméméhna nunjukkeun yén statin ngamajukeun apoptosis (maot sél alami) dina sababaraha jinis kanker, sareng panemuan ieu nunjukkeun yén éta tiasa mangpaat pikeun ngubaran kanker ieu. Dina ulikan ieu, peneliti manggihan yén simvastatin ningkatkeun efficacy of Venetoclax ngalawan leukemia limfositik kronis dina model mouse. Éta ngabantosan ngirangan limfoma ku cara ningkatkeun sinyal apoptosis dina sél kanker, nyababkeun paningkatan waktos salamet. Éta ogé nunjuk kaluar yén Pananjung ieu leuwih éféktif batan sagala ubar dibikeun nyalira.
The researchers were encouraged by the results of this study and began three clinical trials involving the testing of Venetoclax for the treatment of chronic lymphocytic leukemia, looking for data on patients who had received statins. They found that these patients responded better to cancer by 2.7 times than those who did not take statins.
Panaliti nyarios yén upami statin gaduh pangaruh anu sami pikeun manusa, jutaan jalma di panjuru dunya sering ngagunakeunana pikeun nurunkeun kadar kolesterol. Salaku tambahan pikeun ngirangan gajih dina getih, éta ogé parantos kabuktosan teu gaduh efek samping. Panaliti yakin yén uji klinis kedah dilakukeun pikeun nangtoskeun naha statin tiasa ningkatkeun ramalan pasién anu leukemia sareng kanker getih sanés.
