Vatsvakurudzi vepaYunivhesiti yeNew South Wales muSydney uye California Institute of Biomedicine (CALIBR) vakaratidza kuti "masero anouraya ane tsika" anogona kushandiswa kurapa kenza yepancreatic. Muchidzidzo ichi, timu yakawana pancreatic cancer maseru kubva kuvarwere vane advanced pancreatic cancer ndokuvaisa mumakonzo. Wobva wagadzirisa masero ezvirwere zvemurwere kuti anyatso ziva uye abvise maseru egomarara, ndosaka achidaidzwawo kuti masero emhondi ane tsika kana CAR-T masero. Mushure mekunge masero eCAR-T aya abaiwa mumakonzo, akakwanisa kuwana maseru ese egomarara mumuviri, ndokunamatira paari kuburikidza nemakasi epamusoro, uye ndokuparadza maseru egomarara. Mushonga wekurapa wakakosha, uye maseru ekenza mumakonzo anonyangarika zvachose, kusanganisira maseru ekenza akapararira kuchiropa nemapapu. Ichi chidzidzo chakakosha chakaburitswa munguva pfupi yapfuura mupepanhau repamusoro rezvidzidzo Gut.
Vatsvagiri havana kungoratidza kushanda kweiyo CAR-T immunotherapy yepancreatic cancer. Panguva imwecheteyo, tekinoroji nyowani yakaunzwa kuti ivabatsire kudzora zvizere basa remasero eCAR-T. Ichishandisa inonzi "switchable CAR-T masero," timu yakashandisa iyi pfungwa nyowani mupancreatic cancer kekutanga uye yakakamura kucherechedzwa kwechinangwa chegomarara uye kuuraya kwakazotevera kenza kuita maitiro maviri akasiyana. Dr. Alexandra Aicher, mumwe munyori weYunivhesiti yeNew South Wales School of Medicine, akataura kuti CAR-T cell therapy ine simba zvikuru asi inoda kunyatsoshandiswa.
Chikwata ichi chava kutarisira kuunza chirwere ichi chinovimbisa kukiriniki uye chiri kutsvaga mari yekufambira mberi. Muzvinafundo Chris Heeschen, anotungamira munyori weYunivhesiti yeNew South Wales Chikoro cheMishonga, akati danho rinotevera nderekubatanidza masero eCAR-T nekurapa kuita kuti masero eCAR-T asvike maseru ekenza zviri nyore.
