Baarayaasha Jaamacadda New South Wales ee Sydney iyo Machadka California ee Biomedicine (CALIBR) waxay muujiyeen in "unugyada dilaaga ah ee sida gaarka ah u abaabulan" loo isticmaali karo daaweynta kansarka ganaca. Daraasadda, kooxdu waxay ka heleen unugyada kansarka ganaca unugyada bukaanka qaba kansarka ganaca ee horumarsan waxayna ku beeleen jiir. Kadibna wax ka beddel unugyada difaaca bukaanka si gaar ah loo aqoonsado loona tirtiro unugyada kansarka, waana sababtaas sababta loogu yeero unugyada dilaaga ah ee sida gaarka ah u carbisan ama unugyada CAR-T. Ka dib markii unugyadan CAR-T lagu duray jiir, waxay awoodeen inay ka helaan dhammaan unugyada kansarka ee jirka ku jira, iyaga ugu hoggaansamaan astaamaha dusha sare, ka dibna baabi'iyaan unugyada kansarka. Saameynta daaweynta waa mid aad u muhiim ah, unugyada kansarka ee jiirka ayaa gebi ahaanba baaba'aya, oo ay ku jiraan unugyada kansarka ee ku faafay beerka iyo sambabada. Daraasaddan taariikhiga ah ayaa dhowaan lagu daabacay joornaalka akadeemiyadda sare ee Gut.
Cilmi-baarayaashu kaliya ma muujin waxtarka tallaalka cusub ee CAR-T ee kansarka ganaca. Isla mar ahaantaana, tignoolajiyad cusub ayaa la soo bandhigay si ay uga caawiso inay si buuxda u xakameeyaan dhaqdhaqaaqa unugyada CAR-T. Isticmaalka waxa loogu yeero "unugyada CAR-T ee la bedeli karo," kooxdu waxay u adeegsatay fikradan cusub kansarka ganaca markii ugu horeysay waxayna u qaybisay aqoonsiga bartilmaameedka kansarka iyo dilaaga unugyada kansarka ee ku xiga laba hab oo kala duwan. Dr. Alexandra Aicher, oo ah qoraa la-xidhiidha qoraaga Jaamacadda New South Wales School of Medicine, ayaa sheegtay in daawaynta unuggu ee CAR-T ay aad u awood badan tahay balse ay u baahan tahay in si taxadar leh loo maareeyo.
Kooxda ayaa hadda rajeyneysa inay keenaan daaweyntan rajada leh rugta caafimaadka waxayna raadineysaa maalgelin si ay horumar u sameyso. Professor Chris Heeschen, oo ah qoraaga hormoodka ah ee Jaamacadda New South Wales School of Medicine, ayaa sheegay in talaabada xigta ay tahay in la isku daro unugyada CAR-T iyo daaweynta si looga dhigo unugyada CAR-T inay si fudud ku gaaraan unugyada kansarka.
