23 Kurume 2023: Iyo preclinical uye yekutanga-danho kenza maseru ekurapa ari kugadzirwa neShanghai biotech Oricell awana imwe madhora makumi mana nemashanu emamiriyoni emari, kambani yakazivisa neChipiri.
Kutevera kuratidzwa kuASCO gore rapfuura neGPRC5D-inotungamirwa CAR-T kurapwa kweakawanda myeloma, Oricell akakwidza $120 miriyoni Series B muna Chikunguru. Vatsva vemariyori vatsva Qiming Venture Partners uye C&D Emerging Indasitiri Equity Investment inoteverwa nevaivepo vatengesi RTW Investments neQatar Investment Authority yakatungamira kusimudzwa kwazvino, kuri kuwedzera kwechikamu ichocho.
Kambani yebiotech yakataura kuti mari ichangobva kuwanikwa yaizoshandiswa kunyanya kutsvaga kwekiriniki muUS.
Oricell ari kushanda pane akati wandei CAR-T kurapwa and solid tumour antibody candidates. A group of patients with treatment-resistant akawanda myeloma responded to Oricell’s GPRC5D-directed CAR-T with a 100% overall response rate and 60% stringent complete response in the Phase I trial that was presented at ASCO.
Unogona kuda kuverenga: CAR T-Cell kurapa muChina
Kunyanya, Oricell akasimbisa boka revarwere vashanu vakanga vatogamuchira BCMA CAR-T kurapa. Sekureva kwekambani, mhinduro imwe chete, mbiri "mhinduro dzakanaka kwazvo," uye mhinduro mbiri dzakaomarara dzakagamuchirwa dzese. Uye nekutevera kwepakati kubva pamazuva makumi matatu nemashanu kusvika kumazuva 35, ese aive asingafambire mberi pamusi wekupedzisira paASCO.
Sekureva kwaOricell, iyo parizvino iri muchikamu chekugonesa IND, inotarisira kuwedzera muyedzo wayo weGPRC5D-inotungamirwa CAR-T kurapwa kuUS.
Pamusoro pezvo, Oricell ine GPC3-inotungamirwa neCAR-T cell therapy inonzi Ori-C101, iyo iri kudzidza mune advanced hepatocellular carcinoma.
CAR T-Cell kurapa is among the breakthrough treatments for certain types of blood cancers. There are more than 750 ongoing kliniki miedzo in CAR T-Cell therapy in China at present. Patients who wish to enroll can contact the CancerFax runhare rwekubatsira murwere paWhatsApp + 91 96 1588 1588 kana email ku info@cancerfax.com.
