Brukinsa zanubrutinib

Dis 2021: BRUKINSA (Zanubrutrinib) waa daawo la soo qoray oo ka timid BeiGene ltd. BRUKINSA waxaa loo isticmaalaa in lagu daweeyo dadka waaweyn ee qaba Mantle cell lymphoma (MCL), Waldenström macroglobulinemia (WM) iyo lymphoma aagga marginal (MZL) kuwaas oo lahaa ugu yaraan hal ka hor. kansarka daaweynta. Waldenström macroglobulinemia waa nooc ka mid ah macroglobulinemia oo uu keeno Waldenström's (WM). Bukaanku way awoodaan ka iibso Brukinsa online.

Marka la qaato wadarta qiyaasta maalinlaha ah ee la oggol yahay ee 320 mg, BRUKINSA® (zanubrutinib) ayaa la ogaaday in ay xannibto 100 boqolkiiba BTK unugyada dhiigga iyo 94 boqolkiiba ilaa 100 boqolkiiba BTK ee qanjidhada qanjidhada. Saamaynta gabi ahaanba joojinta BTK ee natiijooyinka daaweynta wali lama go'aamin.

BRUKINSA waa daawaynta dadka loo sameeyay ugu yaraan hal daawaynta hore ee lymphoma unugga mantle (MCL).

Oggolaanshaha BRUKINSA waxay ku salaysnayd heerka jawaabta. Isticmaalkan weli waa la qiimeeyaa si loo eego haddii ay leedahay wax faa'iido caafimaad ah. BRUKINSA looma yaqaan inay badbaado ama waxtar u leedahay carruurta.

Borotiinka Bruton's tyrosine kinase (BTK) wuxuu xiriir la leeyahay MCL.

Waa maxay sababta BTK inhibitor u caawiso daaweynta lymphoma unugga mantle (MCL)?

MCL waxaa keena unugyada B-ka ee xun kuwaas oo si degdeg ah u faafo.
BTK (Bruton's tyrosine kinase) waa borotiin ka caawiya unugyada B ee malignantiga ah inay koraan oo faafiyaan iyaga oo u soo diraya calaamadaha.
Xayiraadda BTK waxay kaa caawin kartaa in la joojiyo calaamadaynta.
Saamaynta gabi ahaanba joojinta BTK ee natiijooyinka daaweynta wali lama go'aamin.

Sidee buu u shaqeeyaa Brukinsa?

Labadii daraasadood ee caafimaadka, Bukaannada 118 iyadoo MCL ay heshay brukinsa ka dib ugu yaraan 1 daawayn kahor. Labada daraasadood ee bukaan-socodka, 84% bukaanku waxay ka jawaabeen daaweynta, oo loo yaqaan heerka jawaabta guud iyo ku dhawaad ​​​​80% ayaa sii waday inay ka jawaabaan hal sano ama ka badan. 

Waa maxay dhibaatooyinka ka iman kara Brukinsa?

BRUKINSA waxa laga yaabaa inay keento waxyeelo halis ah, oo ay ku jiraan:

Dhiigbax waa dhibaato dhiigbax oo khatar ah oo keeni karta dhimasho. Haddii aad sidoo kale qaadanayso khafiifiye dhiig, khatarta dhiigbaxa way kordhi kartaa. Haddii aad leedahay calaamado ama calaamado dhiigbax, u sheeg dhakhtarkaaga, oo ay ku jiraan:

• dhiig saxaradaada ama saxaradaada madow (waxay umuuqdaan daamur)
• kaadi casaan ama bunni ah
• dhiig bax lama filaan ah, ama dhiigbax daran ama aanad xakamayn karin
• matag dhiig ama matag u eg qaxwaha
• qufaco dhiig ama xinjirowga dhiigga
• nabarro kordhay
• dawakhaad
• daciifnimo
• wareer
• isbedelka hadalkaaga
• madax xanuun waqti dheer qaata.

Infections taasi waxay noqon kartaa halis waxayna keeni kartaa dhimasho. Isla markiiba u sheeg bixiyaha xanaanada caafimaadkaaga haddii aad leedahay qandho, qarqaryo, ama calaamado hargab oo kale ah.

• Hoos u dhaca tirada unugyada dhiigga. Hoos u dhaca tirooyinka dhiigga (unugyada dhiigga cad, platelets, iyo unugyada dhiigga cas) waxay ku badan yihiin brukinsa, laakiin sidoo kale waxay noqon karaan kuwo daran. Bixiyahaaga daryeelka caafimaadku waa inuu sameeyaa shaybaadhka dhiiga inta lagu jiro daawaynta BRUKINSA si loo eego tirada dhiigaaga.
• Kansarrada asaasiga ah ee labaad. Kansarro cusub ayaa ku dhacay dadka inta lagu jiro daawaynta BRUKINSA, oo ay ku jiraan kansarrada maqaarka. Isticmaal ilaalinta qorraxda marka aad dibadda joogto iftiinka qorraxda.
• Dhibaatooyinka garaaca wadnaha (atrial fibrillation iyo atrial flutter). U sheeg bixiyaha xanaanada caafimaadkaaga haddii aad leedahay mid ka mid ah calaamadaha soo socda:
  
  • garaaca wadnahaagu waa mid deg deg ah ama aan caadi ahayn
  • Dareen madax ama wareer
  • dhaaf (suuxsan)
  • neefta oo ku qabata
  • raaxo xanuun laabta

Sidee loo qaataa Brukinsa?

Qiyaasta lagu taliyey ee BRUKINSA waa 320 mg maalintii, taas oo ah afar kaabsal oo 80-mg ah. Waxa laga yaabaa in dhakhtarkaagu kugula taliyo qaadashada brukinsa: laba jeer maalintii ama hal mar maalintii.

Kaabsoosha BRUKINSA waa in lagu wada qaadaa biyo-ha furin, jabin, ama calallin. BRUKINSA waxa lagu qaadan karaa cunto ama la'aan.

Qiyaastaada iyo jadwalkaaga ayaa laga yaabaa in la beddelo ama la joojiyo dhakhtarkaaga si uu u daboolo baahiyahaaga daawaynta ee gaarka ah oo ay ku jiraan maaraynta waxyeelada.

Codsiyo 

Ansixinta sida Dec 2021.

BRUKINSA waxaa lagu ansixiyay calaamadaha soo socda iyo gobollada:

• Daawaynta lymphoma unugga mantle (MCL) ee bukaanada qaangaarka ah ee helay ugu yaraan hal daawayn kahor (Mareykanka, Noofambar 2019)^a;
• Daawaynta MCL ee bukaanada qaangaarka ah ee helay ugu yaraan hal daawayn kahor (Shiinaha, Juun 2020) ^b;
• Daawaynta leukemia dabadheeraad ah (CLL) ama lymphocytic lymphoma yar (SLL) ee bukaanada qaangaarka ah ee helay ugu yaraan hal daawayn kahor (Shiinaha, Juun 2020) ^b;
• Daawaynta soo laabatay ama MCL (United Arab Emirates, February 2021);
• Daawaynta Waldenström macroglobulinemia (WM) ee bukaanka qaangaarka ah (Kanada, Maarso 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba WM ee helay ugu yaraan hal daawayn kahor (Shiinaha, Juun 2021)^b;
• Daawaynta MCL ee bukaanka qaangaarka ah ee helay ugu yaraan hal daawayn hore (Kanada, Luulyo 2021);
• Daawaynta MCL ee bukaanka qaangaarka ah ee helay ugu yaraan hal daawayn hore (Chile, Luulyo 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba MCL ee helay ugu yaraan hal daawayn hore (Brazil, Ogosto 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba WM (Mareykanka, Ogosto 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba lymphoma aagga marginal (MZL) kuwaas oo helay ugu yaraan hal nidaam anti-CD20 ku salaysan (Mareykanka, Sebtembar 2021)*;
• Daawaynta bukaanada qaangaarka ah ee qaba MCL ee helay ugu yaraan hal daawayn hore (Singapore, Oktoobar 2021);
• Daawaynta MCL ee bukaanada helay ugu yaraan hal daawayn hore (Israel, Oktoobar 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba WM ee helay ugu yaraan hal daawayn hore, ama daawaynta safka kowaad ee bukaanada aan ku haboonayn kiimiko-immunotherapy (Australia, Oktoobar 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba MCL ee helay ugu yaraan hal daawayn hore (Australia, Oktoobar 2021);
• Daawaynta bukaanada qaangaarka ah ee qaba MCL ee helay ugu yaraan hal daawayn hore (Ruushka, Oktoobar 2021);
• Daawaynta lymphoma unugga mantle (MCL) ee bukaannada qaangaarka ah ee helay ugu yaraan hal daawayn hore (Sacuudi Carabiya, Noofambar 2021); iyo
• Daawaynta bukaanada qaangaarka ah ee qaba WM kuwaas oo helay ugu yaraan hal daawayn hore ama daawaynta safka kowaad ee bukaanada aan ku haboonayn kiimiko-immunotherapy (Ururka Yurub, Noofambar 2021).

Qiimaha Brukinsa ee Hindiya

The Qiimaha kaabsal afka ee Brukinsa 80 mg ayaa u dhexeeya $ 3500-4000 sahayda 120 kaabsoosha, waxay kuxirantahay farmasiga aad booqato.

Ma ka iibsan karaa Brukinsa online?

Haa, waxaad ka iibsan kartaa Brukinsa online. Farmasiyo badan oo onlayn ah ayaa ku iibinaya onlayn laakiin wata warqad dhakhtar oo sax ah.

Wixii macluumaad dheeraad ah fadlan wac, fariin ama WhatsApp +91 961588 1588.

Fadlan guji halkan si aad u qorto macluumaadka Brukinsa.