Waxa jira horumarkii ugu dambeeyay ee kansarka sambabada unugyada aan yarayn. Nooc ka mid ah tallaal daaweyn kara kansarka sanbabada ee aan yareyn (NSCLC) waxay soo martay marxaladda 3 ogolaanshaha daaweynta waxayna leedahay saameyn daaweyn oo weyn oo ku saabsan cudurka sambabada ee unugyada yar. Hada waa laga heli karaa wadamo aad u tiro yar.
As an anti-idiotype monoclonal antibody, the vaccine enables lung cancer patients to respond strongly to specific glycosylated gangliosides (NeuGcGM3) in cancer cells. Compared with the best supportive care, lung tallaalka kansarka waxay wanaajin kartaa heerka badbaadada bukaanada leh marxaladda dib u soo noqoshada iyo horumaray (marxaladda IIIB / IV) NSCLC.
Rather than numerous warm blooded creatures, including gorillas, we can’t recognize the nearness of NeuGcGM3 gangliosides in typical human tissues and liquids. Be that as it may, NeuGcGM3 gangliosides are profoundly communicated in certain human malignant growth cells. In non-little cell lung malignancy tests, gangliosides were identified in over 90% of non-little cell lung tumors. Thusly, NeuGcGM3 ganglioside can be utilized as a ground-breaking objective for lung malignant growth antibodies.
Ka dib markii qaabdhismeedka aan la fahmi karin uu soo saaro unugyada difaaca jirka oo cad antigen, waxay abuuri kartaa unugyada difaaca jirka ee ka soo horjeeda gaar ahaanshaha antigen-ka ugu weyn, kaasoo xakameyn kara qaabka iska caabinta gudaha. Ka dib markii laga tallaalay koritaankaan xun ee sambabka tallaal, it can advance the generation of antibodies against this antigen, assigned Ab1. These Ab1 antibodies are fit for delivering a progression of hostile to idiotypic antibodies, assigned Ab2. The idiotypes of these exceptional antibodies are fused into the antigen-restricting site of Ab1, with the goal that these extraordinary antibodies produce a particular resistant reaction to regular antigens. Hence, vaccination with Ab2 immunizer can advance the creation of Ab3 (hostile to against idiotype neutralizer), and this Ab3 counter acting agent can perceive the first antigen perceived by Ab1. Some Ab2 antibodies of this sort invigorate the safe framework to actuate defensive resistance against buro antigens.
Waxaa caafimaad ahaan lagu muujiyey in cudurka sambabka tallaal aad buu u adkaystay oo wuxuu ku fiicnaaday dil toogasho. Calaamado fara badan oo aasaasi ah ayaa ka dhaca deegaanka oo keliya (goobta faleebo) oo guud ahaan waa kuwo jilicsan oo dherer kooban. Iyadoo aan loo eegin haddii antibody-ka la siiyo bukaanka ka dib markii xaaladoodu kala tagtay, adkeysigooda guud wuu soo fiicnaaday.
Waqtigan xaadirka ah, tallaalka noocan ah ee tallaalka koritaanka halista ah ayaan lagu dhiirrigelinin Hindiya.
