Janaayo 2023: Xarunta caafimaadka ee Asan (AMC) ayaa furtay xaruntii ugu horaysay ee daawaynta unug CAR-T ee dalka ka dib markii ay dawladu ansixisay faa'iidooyinka caymiska caafimaadka ee Kymriah's CAR-T therapy cell.
AMC ayaa Talaadadii ku dhawaaqday in cisbitaalkeeda kansarka uu furay xarun CAR-T oo uu bilaabay bixinta kharashka daawaynta Kymriah ee uu ansixiyay Novartis.
Daawaynta CAR-T, unugyada difaaca (unugyada T) ee bukaanka ayaa laga saaraa oo lagu beddelaa qaboojiyeyaasha antigen-ka ee chimeric kuwaas oo bartilmaameedsada unugyada kansarka gaarka ah. Bukaanka ayaa markaa lagu duraa unugyada T si loo ciribtiro unugyada kansarka.
When treating patients with relapsed and refractory B-cell acute lymphoblastic leukaemia (ALL) who are 25 years of age or younger as well as individuals with refractory diffuse large B-cell lymphoma, Kymriah is covered by insurance (DLBCL).
Unugyada B ee soo noqnoqday iyo kuwa soo noqnoqday iyo DLBCL dib u soo noqday ayaa aad ugu dhib badnaa in la daweeyo ilaa hadda, iyada oo badi bukaannadan ay si dhib yar u nool yihiin lix bilood ka dib ogaanshaha.
Marka loo eego tirakoobka, CAR-T daaweyntu waxay dishaa kansarka 50% bukaanada qaangaarka ah ee qaba dib u soo noqoshada DLBCL iyo ku dhawaad 80% bukaanada carruurta ee leh soo noqoshada iyo dib u celinta B-cell ALL.
Sawirka: Baby Lee oo helay hadiyad yar oo kirismaska ah Professor Ho Joon Im (Courtsey: websaydka Xarunta caafimaadka Asan)
Bukaannada qaangaarka ah oo keliya ayaa lagu arki doonaa xarunta AMC ee CAR-T takhaatiirta kansarka Yoon Dok-hyun, Cho Hyung-woo, iyo dhakhaatiirta dhiiga ee Lee Jung-hee iyo Park Han-seung.
Im Ho-joon, Koh Kyung-nam, Kim Hye-ry, iyo Kang Sung-han, dhakhaatiirta dhiigbaxa-kankolojiyada carruurta, ayaa bixin doona daryeel bukaanada da'da yar.
Yoon Dok-hyun, oo ah maamulaha xarunta CAR-T ee AMC, ayaa sheegay in inkasta oo daawaynta CAR-T ay leedahay saameyn aad u weyn, ay sidoo kale keeni karto waxyeelo xun. Rugta edbinta ugu horraysa ee daawaynta CAR-T waxaa soo saartay xarunta AMC ee CAR-T iyadoo la kaashanaysa waaxyo badan, oo ay ku jiraan unugga daryeelka degdegga ah, neerfaha, iyo cudurrada faafa, si loo dhiso hab-raacyo lagu ogaanayo dhibaatooyinka soo raaca goor hore oo loo bixiyo daawaynta badbaadsan.
