Abincin “ci” kansar kansa
A shekarar 2014, Mista Yang dan shekara 65 da matarsa sun yi tafiya zuwa kasashen waje. A lokacin, alamun rashin lafiya na ciki da alamomin maƙarƙashiya sun faru, amma ba su mai da hankali sosai a lokacin ba, suna tunanin cewa ba su gamsu da ƙasa da ruwa ba. Bayan dawowa China, alamun cutar sannu a hankali.
On National Day in 2014, when his son, daughter-in-law, and grandson went home for the holiday, Mr. Yang suddenly had nausea and vomiting when he went to the restaurant to eat. Everyone quickly took him to a nearby large hospital for an examination. Immediately apply for hospitalization.
However, even greater bad news fell from the sky. Further examination showed that Mr. Yang had not appendicitis but maganin ciwon daji.
A watan Nuwamba, Mista Yang ya sami aikin laparoscopic na dama semicolon. Yawancin lokaci, hangen nesa na cutar sankarau a gefen dama yana da muni fiye da na gefen hagu, amma sa'a, Mista Yang ya same shi da sauri kuma aikin yana da sauƙi. Pathology ya nuna cewa shine mataki na II, wanda ya ɗan fara da wuri.
Bayan tiyatar, Mista Yang ya koma rayuwarsa ta yau da kullun bayan hutu.
Chemotherapy is not effective, the genetic test is negative, is there any help for advanced colorectal cancer?
In May 2016, Mr. Yang clearly felt that he was always tired and fatigued. Sure enough, CT review showed nodules in the anastomosis of the previous operation. Further examination confirmed the recurrence of colorectal cancer and the metastasis of peritoneum and lymph nodes.
He immediately received the FOLFIRI ± cetuximab regimen, but the effect was not satisfactory. Under the advice of the doctor, he conducted a genetic test, and now there are many targeted and immunotherapy magunguna a kasuwa. Idan akwai maye gurbi, yana iya kasancewa Akwai rufin azurfa. Koyaya, sakamakon ya kasance abin ƙyama. Gwajin bai sami maye gurbi mai ma'ana ba, kuma microsatellite din tana da karko, wanda ke nufin cewa ba za a iya amfani da masu hana kariya na kariya wadanda ake daukar su a matsayin raunin ceton rai daga marasa lafiya.
Alurar rigakafin kwayar halitta ta Dendritic tana kawar da duk lahani
Just when the whole family was in despair, a friend in the medical circle recommended Mr. Yang to go to Japan to try dendritic cell vaccine treatment.
This is a dendritic cell vaccine that specifically identifies cancer cells in patients by extracting their own tumor cell antigens, because this is an advanced cell immunotherapy, has no side effects, and even cooperates with normal chemotherapy and targeted therapy Can also increase the effect.
I asked the attending doctor in Sin, and it was also recognized. The doctor said that although it is impossible to cure, Japan’s cell immunotherapy is indeed at the global leading level. If the economic conditions allow, you can try to achieve the purpose of prolonging survival and improving the quality of life.
A watan Agustan 2016, Mista Yang da matarsa sun isa Japan.
Da farko likitocin kasar Japan sun gudanar da cikakken gwajin aikin rigakafin sa kuma sun gano cewa adadin kwayar T a jiki yayi kadan, ma'ana, karfin jikin da zai kashe kwayoyin cutar kansa bai isa ba. Adadin wannan zai taimaka wa cutar sankara da kuma maganin rigakafin dendritic daga baya, yayin ɗiban jini don shirya rigakafin ƙwayoyin dendritic.
Nan da nan bayan kammala sakewarsa ta farko, babban abin da Mista Yang ya fahimta shi ne ya ji cikakken karfi a jikinsa. Ya kasance yana jin rauni da rauni, kuma an sauƙaƙe alamun cutar. Tare da ci, zai iya cin ɗan abinci mara nauyi. abinci.
A watan Oktoba 2016, Mista Yang ya fara shiga aikin maganin rigakafin kwayar halitta dendritic sau daya a kowane mako biyu.
A watan Janairun 2017, sakamakon binciken na PET ya ba kowa mamaki, kuma raunin da akai akai ya bace.
A watan Janairun 2018, sakamakon sake dubawar da Mista Yang ya yi ya sake nuna cikakkiyar gafartawa, kuma an cire cututtukan da ke cikin jikin gaba ɗaya.
A halin yanzu, an daidaita tsarin maganin Mista Yang don ya dawo sau daya a kowane watanni shida don hana sake afkuwar hakan. Ya zuwa yanzu, Mista Yang na cikin koshin lafiya kuma ya koma rayuwarsa ta yau da kullun.
Menene maganin rigakafin kwayar halitta dendritic?
After reading Mr. Yang’s case, I believe that many patients who are not effective for chemotherapy and whose genetic testing does not have targeted drugs see hope.
Dendritic cell vaccine is an ideal therapy. We all know that one of the reasons for the formation of cancer is that cancer cells hide very well. Dendritic cells cannot recognize cancer cells. Imagine that you can put your own cancer cells and dendrites. The cells are fused to form dendritic cells that carry specific antigens on the surface of various cancer cells. These dendritic cells have the ability to recognize tumo cells. When we put these cells back into the conductor, he will teach somatic cells to recognize different Cancer antigen cancer cells, one group to find a antigen, one group to find b antigen cancer cells, all of them are eliminated, and at the same time used in combination with the adjuvant therapy of interleukin 12, which enhances T cells in the body, can effectively increase killer T cells The number, so as to achieve the best anti-cancer effect.
Fa'idodi uku na rigakafin ƙwayoyin dendritic
1. Bisa ga takamaiman takamaiman tsari da sake gina garkuwar salula na cikin gida, an fi niyya, mafi daidaito da inganci don cire ƙwayoyin kansa.
Faruwar wasu cututtukan cututtukan ƙwayoyin cuta na yau da kullun da ciwace-ciwacen jiki suna da alaƙa kai tsaye da asara ko lahani na aikin DC, don haka dawo da takamaiman aikin DC a cikin jiki ya zama mabuɗin magani da rigakafin irin waɗannan cututtukan. Saboda amfani da takamaiman babban peptides na epitope, T-DC ya sanya ƙwayoyin T da ke aiki takamaiman kuma aka nufa, da gyara, ya dawo da haɓaka aikin mara lafiyar mara lafiyar, karya tsarin garkuwar jiki da haƙurin gida Karbar jihar, don cimma nasarar sake gina dukkan jiki da rigakafin jikin gida.
2. Ci gaba da fara aikin cirewa tare da rashin cytolysis azaman ainihin yanayin kashewa, tare da babban aminci
Nazarin ya nuna cewa T-DC yafi amfani da tarin cytokines daban-daban a cikin jiki a matsayin babbar hanyar kawar da abin da aka nufa, wanda hakan ya sanya garkuwar garkuwar da aka sake ginawa ta rage lalacewar kwayoyin al'ada yayin cire abin.
3. Yana da tasirin dogon lokaci na halayen alurar riga kafi kuma ya fahimci haɗin ƙwayoyin cuta na rigakafi da magani
DC ɗin da aka sake gina shi a cikin vitro na iya kunna ƙwayoyin T masu hutawa don samar da amsawar rigakafi na farko lokacin da aka sake dawo da su cikin jiki, kuma za a iya ƙara ƙwayoyin T da ke kunnawa kuma su ƙara ƙaruwa. Daya daga cikin dendrite zai iya kunna ƙwayoyin 100-3000 T. Yawancin kwayoyin T masu tasiri suna taka rawa wajen cire ƙwayoyin cuta, kuma ɗayan ɓangaren zai rayu shekaru da yawa zuwa shekaru da yawa don zama ƙwayoyin T. Lokaci na gaba da suka gamu da ƙananan antigens, zazzabi mai ƙarfi mai ƙarfi zai faru. Sabili da haka, tsarin kariya na rigakafi wanda ya dogara da gyaran T-DC da sake ginawa zai iya ci gaba da aiki shekaru da yawa, kuma zai iya sake shiga cikin sake zagayowar don aiki ƙarƙashin yanayin da ya dace.
Wadanne marasa lafiya ne ke iya karɓar maganin rigakafin ƙwayar dendritic?
Ya kamata a lura cewa maganin alurar rigakafin kwayar dendritic ba shi da wani tasiri a bayyane kan rage tumbin marasa lafiya da ke fama da cutar kansa, kuma marasa lafiya da ke fama da cutar kansa suna da tasirin tsawaita rayuwa yayin kiyaye ingancin rayuwa; azaman magani na adjuvant bayan tiyata, zai iya kawar da sake dawowa da kuma magance Tasirin ana iya kiyaye shi na dogon lokaci; haɗe tare da wasu hanyoyin kwantar da hankali irin su chemotherapy, magungunan da aka yi niyya, masu hana PD1, sakamakon zai fi kyau. Saboda haka, waɗannan nau'ikan marasa lafiya guda biyar sune mafi dacewa:
- Marasa lafiya marasa lafiya kafin ayi musu tiyata, jinkirin murmurewa bayan tiyata, da kuma fargabar ƙwayoyin cuta na ɓoye ba a kawar da su gaba ɗaya.
- After radiotherapy and chemotherapy, immunity is low, and side effects are obvio
mu (kamar rashin ci, tashin zuciya, zubewar gashi, kumburin fata, da sauransu), marasa lafiyar da ke sa ran ƙara tasirin tasirin cutar. - Dangane da tsoron illolin da ke tattare da aikin rediyo da kuma maganin ƙwaƙwalwa, marasa lafiyar da ke fatan yin amfani da magunguna daban-daban don cimma tasirin warkewa.
- Kwayoyin sankara a cikin ciwace-ciwacen ci gaba sun bazu cikin jiki, amma hanyoyin jiyya na yau da kullun ba su da ƙarfi, kuma marasa lafiya waɗanda ke tsammanin tsawaita rayuwa da haɓaka ƙimar rayuwa.
- Marasa lafiya masu karɓar masu hana kariya
Mainly applicable to solid tumors: head and neck tumors, esophageal cancer, lung cancer, gastric cancer, breast cancer, liver cancer, pancreatic cancer, colorectal cancer, ovarian cancer, cutar sankarar mahaifa, renal cancer, prostate cancer, malignant melanoma, sarcoma, partial malignancy Lymphoma.
Ta yaya marasa lafiya na gida ke karɓar maganin rigakafin ƙwayoyin dendritic?
A halin yanzu, babu ayyukan gwaji na asibiti da yawa da aka amince da su don magance rigakafin salula a cikin Sin, kuma har yanzu ba a taɓa faɗakar da darajar, aminci da yuwuwar maganin kwayar DC ba. An yi imanin cewa da zarar an ƙaddamar da manufar gaba ɗaya, za ta fitar da aiwatar da ƙa'idodin aikin kulawa na asibiti da ƙa'idodi a cikin Sin da ƙara sabbin zaɓuɓɓuka don kula da masu cutar kansa a China. A Amurka, Jamus, Japan da sauran ƙasashe waɗanda ke da ƙa'idodin aikin likita, haɓakawa da aikace-aikacen asibiti na ƙwayoyin dendritic suna kan gaba a duniya. An sami nasarar inganta allurar rigakafin ƙwayoyin cuta na Dendritic a cikin Jamus da Japan kuma sun shiga aikace-aikacen asibiti. Kuna iya kimantawa da amfani ta hanyar Yanar gizo Oncologist Network (+ 91 96 1588 1588).
Ya kamata a sani cewa tasirin kwayar cutar sankarau a kan kankancewar ciwace-ciwace a cikin marasa lafiya masu fama da cutar kansa ba bayyananne bane. Ga marasa lafiya masu fama da cutar kansa, yana da tasirin tsawaita rayuwa yayin kiyaye ingancin rayuwa; a matsayin magani na adjuvant bayan tiyata, zai iya kawar da sake dawowa da tasirin warkewa Kula da lokaci mai tsawo; haɗe tare da chemotherapy, magungunan da aka yi niyya, masu hana PD1 da sauran hanyoyin kwantar da hankali, sakamakon zai fi kyau.
Cellular immunotherapy is not suitable for all cancer patients. For example, the sarcoma of Wei Zexi is a rare tumor with a high degree of malignancy. There is currently no good treatment in the world. Therefore, cell immunotherapy is naturally not suitable. Therefore, please ensure that you, family members and patients are kept away from false information on the Internet. Before choosing treatment, it must be evaluated by experts in formal and authoritative cancer hospitals. It is very important to choose carefully according to the economic conditions of the family.
