Fabrairu 2024: Tumor-infiltrating lymphocyte (TIL) far jiyya wata hanya ce mai yuwuwa wacce ke amfani da tsarin garkuwar jiki don yaƙar ciwace-ciwace. Wannan yanki na jiyya a kasar Sin yana samun ci gaba cikin sauri saboda karuwar jarin da al'ummar kasar ke yi a fannin aikin likitanci da gyaran kwayoyin halitta, duk da cewa tana da karancin shekaru. Magungunan TIL a kasar Sin suna fuskantar matsaloli kamar rashin isassun kayayyakin more rayuwa, rashin ingantaccen ka'idoji, da rashin isasshen fahimtar zaɓin marassa lafiya da haɗin gwiwar jiyya. Samuwar chimeric antigen receptor (CAR) -T cell magani a kasar Sin ya samar da yanayi mai kyau don ci gaban maganin TIL, inganta haɗin gwiwa tsakanin cibiyoyi da kamfanoni masu zaman kansu.
Ci gaba da Amfani
Dokta Steven Rosenberg ya yi nasarar magance cutar ta'addanci ta linzamin kwamfuta tare da TILs mai sarrafa kansa a ƙarshen 1980s, lokacin da ya fara haɓakawa. Maganin TIL. Tun daga wannan lokacin, maganin TIL ya ci gaba sosai, yana nuna tasiri sosai a cikin takamaiman ciwace-ciwacen ciwace-ciwace, musamman melanoma, kansar mahaifa, da kansar launi.
Kuna so karanta: CAR T-Cell Therapy a China
Gwaje-gwaje na asibiti da Ci gaba
Grit Biotechnology, mai hedkwata a Shanghai, ya sami dala miliyan 60 a cikin kudade na Series B don ciyar da ci gaban ƴan takararta na TIL, tare da fifikon farko kan cutar sankarau, mahaifa, da ciwon huhu. Waɗannan ƙoƙarce-ƙoƙarce sun yi daidai da tsarin duniya a cikin jiyya na TIL, wanda galibi yana haɗa jiyya tare da sauran magungunan rigakafi, kamar wuraren bincike na rigakafi.
Nazarin kwanan nan sun jaddada cewa abun da ke ciki da wuri na TILs a cikin ciwace-ciwacen daji sune mahimman abubuwan da suka shafi tsinkaya da sakamakon magani. Fahimtar ƙaƙƙarfan alaƙar da ke tsakanin TILs da ƙananan ƙwayoyin cuta yana da mahimmanci don haɓaka maganin TIL wanda aka keɓance da takamaiman nau'ikan ƙari da kuma daidaita rarraba marasa lafiya.
Shirye-Shirye masu zuwa
Manyan dalilai da yawa suna buƙatar kulawa don cikakken amfani da yuwuwar TIL magani a China.
Daidaitawa: Daidaitawa ya ƙunshi ƙirƙira daidaitattun ka'idoji don warewar TIL, haɓaka, da bayarwa don ba da damar kwatanta sauƙi tsakanin karatun asibiti da haɓaka fahimtar sakamakon gwaji.
Zaɓin mara lafiya: Haɓaka ƙwaƙƙarfan fa'idodin biomarker don zaɓin dogara ga marasa lafiya waɗanda za su amfana daga maganin TIL yana da mahimmanci don ingantaccen rabon albarkatu da haɓaka tasirin jiyya.
Haɗin kai: Ƙarfafa haɗin gwiwa tsakanin cibiyoyin ilimi, asibitoci, da abokan haɗin gwiwar masana'antu za su inganta ƙididdigewa da kuma hanzarta fassarar ingantaccen maganin TIL zuwa aikin asibiti.
ilimi: Bayar da shirye-shiryen horarwa na musamman da albarkatun ilimi don ƙwararrun kiwon lafiya waɗanda ke tsunduma cikin Maganin TIL zai haɓaka mafi kyawun ayyuka da kuma ƙara wayar da kan jama'a game da ci gaban da ake samu a yankin.
Kuna so karanta: CAR T Cell far don Multi myeloma a China
Kara mai da hankali kan bincike da ilimi a kasar Sin zai taimaka wa ci gaban fasahar TIL don inganta ciwace-ciwacen ciwace-ciwace ta hanyar inganta kirkire-kirkire da samar da amintattun jiyya.
Menene halin da ake ciki a halin yanzu na ƙwayar cutar ƙwayar cuta ta lymphocyte a China?
Tumor-infiltrating lymphocyte (TIL) therapy is still at an advanced stage in China. According to recent rumors, the US Food and Drug Administration may provide approval to employ TIL treatment to treat some cancers. It has great promise for treating solid cancers. Using chimeric antigen receptor (CAR)-T cells for treatment has sped up the growth of TIL therapy in China, making it easier for companies that work in cell therapy and gene editing to do well.
Mahimman halaye na maganin TIL a China sune:
• Iyakantattun ababen more rayuwa da ƙayyadaddun ka'idoji
• Mai da hankali kan melanoma, mahaifa, da kansar launin fata
• Haɗin kai tare da ƙungiyoyin ƙasa da ƙasa da kamfanoni masu zaman kansu
• Shirye-shiryen ilimi don ƙwararrun likita
Yayin da maganin TIL ya nuna nasara mai ban mamaki a cikin takamaiman nau'in ƙari, aiwatar da shi yana da wahala saboda dalilai kamar ƙarancin amfanin TIL, rashin dacewar TIL bayan jiko, da ƙalubalen haɓaka ƙa'idodi masu dacewa.
Dama a gaba don maganin TIL a China sun haɗa da:
• Daidaitaccen keɓewar TIL, faɗaɗawa, da dabarun gudanarwa
• Ingantattun zaɓin haƙuri da haɗin jiyya
• Inganta haɗin gwiwa tsakanin malamai, asibitoci, da abokan masana'antu
• Fadada albarkatun ilimi don masu samar da lafiya
Wadannan matakan suna da nufin haɓaka amfani da maganin TIL a kasar Sin, a ƙarshe yana haifar da mafi aminci da ingantaccen maganin ƙwayar cuta.
Wadanne nau'ikan ciwon daji ne aka fi sani da maganin TIL?
Mafi yawan nau'o'in ciwon daji da ake bi da su tare da maganin lymphocyte mai shiga ciki (TIL) sune:
Melanoma: Maganin TIL yana da tasiri wajen magance melanoma, irin ciwon daji na fata.
Ciwon daji na mahaifa: Jiyya na TIL ya nuna sakamako mai ban sha'awa a cikin masu ciwon daji na mahaifa, wanda ya haifar da raguwar ƙari da karuwar yawan rayuwa.
Ciwon daji mai launi: Maganin TIL ya nuna nasarar farko a cikin masu fama da cutar kansar launin fata, yana nuna yiwuwar irin wannan ciwon daji.
Yayin da maganin TIL har yanzu yana cikin matakan farko a kasar Sin, ci gaba da bincike da nazarin asibiti suna binciken aikace-aikacensa a cikin ciwace-ciwacen ciwace-ciwace da yawa, yana nuna daidaitawarsa da alƙawarin amfani da shi a nan gaba.
Farashin TIL therapy a China
Maganin TIL yana cikin matakan gwaji a halin yanzu, kuma gabaɗaya Farashin maganin TIL a China na iya zuwa tsakanin $ 60,000 da $ 125,000 USD. Farashin CAR T Cell a China tsakanin $45,000 da $80,000 USD. Kudin maganin TIL na iya bambanta dangane da takamaiman shirin jiyya, asibiti, da sauran dalilai. Ana ba da shawarar tuntuɓar mai ba da lafiya ko asibiti a China don ƙarin bayani kan farashin maganin TIL.
