Gwajin kwayar cutar kansa
Bayan kusan shekaru goma na haɓakawa, gwajin ƙwayoyin cuta na ƙwayar cuta ya zama buƙatar babban adadin masu cutar kansa nan da nan. Jagoran rahoton gwajin da aka bayar ta hanyar gwajin kwayoyin cutar tumo ya yi daidai da ra'ayin ci gaban ingantaccen magani, kuma ya shiga cikin dukkan bangarorin bincike da kuma kula da majinyata. Ga marasa lafiya, za su iya zaɓar magungunan da aka yi niyya don madaidaicin magani, guje wa karkata, da kuma guje wa illolin da ba dole ba. daci.
Matsayi na yau da kullun na maganin cutar kansa
In most cases, surgery is still the main treatment for gastric cancer. However, the heterogeneity of gastric cancer is very strong, and its biological behavior is affected by the huge gene regulation in the cell. Therefore, only by classifying the essential characteristics of gastric cancer from the molecular level can early diagnosis and prognosis judgment of the tumo be more reasonable and accurate , Application of molecular targeted drugs for individualized and precise treatment of patients.
A halin yanzu, an amince da bin magungunan da aka yi niyya:
| Lambar Serial | Target | magani |
| 1 | HER2 | Trastuzumab (Trastuzumab, Herceptin) |
| 2 | VEGFR | Ramucirumab |
| 3 | NTRK | Larotrectinib (LOXO-101) |
| 4 | PD-1 | Pembrolizumab (K magani) |
| 5 | Bayani na VEGFR-2 | Apatinib (Apatinib, Aitan) |
Bugu da ƙari, akwai wasu magungunan da aka yi niyya da yawa waɗanda ke da alaƙa da ciwon daji na ciki a cikin gwaje-gwaje na asibiti, irin su magungunan da ke toshe HER2: lapatinib (Tykerb ®), pertuzumab (Perjeta ®) da trastuzumab emtansine (Kadcyla ®). Magungunan da ke toshe EGFR: Panitumumab (Victibi®) magani ne wanda ke kaiwa ga EGFR da ake gwada cutar kansar ciki.
Cibiyar Sadarwar Oncologist ta Duniya tana tunatar da kowa cewa ana buƙatar gwajin ƙwayoyin cuta kafin maganin da aka yi niyya. Ta hanyar fahimtar nau'in maye gurbi na ƙwayar cuta ne kawai za'a iya samar da ingantaccen tsarin kulawa don amfanin marasa lafiya. Bugu da ƙari, a zaɓin fasahar gwajin kwayoyin halitta, ya zama dole a zaɓi fasahar gwajin da ta dace daidai da maƙasudinta. Ta zaɓar samfuran da Hukumar Abinci da Magunguna ta Jiha ta amince kawai za a iya tabbatar da daidaito da amincin sakamakon gwajin.
Ta yaya marasa lafiya da ciwon daji na ciki suke zaɓar gwajin ƙwayoyin halitta?
Cibiyar Nazarin Oncologist ta Duniya tana tunatar da marasa lafiya cewa gwajin kwayoyin cutar kansa da kuma nazarin jiyya na asibiti wani shiri ne na tsari wanda ke buƙatar goyon bayan dakin gwaje-gwaje mai ƙarfi, ingantaccen gwajin ingancin ingancin gwaji da ƙungiyar nazarin bayanai masu girma. Kyakkyawan gwajin gwajin kwayoyin halitta zai iya guje wa asarar damar jiyya da kuma ceton rayukan masu cutar kansa. A halin yanzu, akwai cibiyoyin gwajin kwayoyin halitta da dama a kasuwa, kuma dole ne marasa lafiya su zabi kamfanonin gwajin kwayoyin halitta a hankali don tabbatar da daidaiton sakamakon gwajin.
Anan ga fasahar gwajin kwayar halitta wacce FDA ta amince da ita!
GidauniyarOne®CDx
Gidauniyar FDA ta amince da FoundationOne theCDx a matsayin farkon samfurin samfuran cututtukan ƙwayar cuta . As a research tool, it assisted the discovery of countless scientific research results, and accumulated a large amount of data during this period. The current test coverage includes 324 genes and two molecular markers (MSI / TMB) that can predict the efficacy of immune checkpoint inhibitors. It can cover all solid tumors (except sarcoma) and can directly correspond to 17 hanyoyin kwantar da hankali da FDA ta amince da su!
Don kimantawa na asibiti na ƙwayoyin cutar kansa, dabarun da aka saba amfani da su sun haɗa da jerin Sanger, mass spectrometry genotyping, fluorescence in situ hybridization (FISH) da kuma nazarin immunohistochemical (IHC). "Ganewar alamar alama guda ɗaya" kamar FISH, IHC da gano wuri mai yawa na gene (hotspot panel) na iya samun nau'i ɗaya ko biyu kawai na rashin lafiyar kwayoyin halitta (kamar maye gurbin tushe kawai). Nazarin ya nuna cewa sabuwar fasaha ta zamani mai zuwa don cikakken gwajin cutar kansa na iya gano duk nau'ikan rashin daidaituwa na kwayoyin halitta guda hudu (maye gurbin tushe; sakawa da gogewa; bambancin lambar kwafi da sake tsarawa), kuma ya fi na gargajiya, daidaitattun gwaje-gwaje.
Ta yaya masu cutar kansar za su iya yin gwaji na FoundationOne® CDx?
A cikin Sin, sabis ne na bincike wanda Dean Diagnostics ya bayar. Hanyoyin sadarwar Oncologist na Duniya na iya taimaka wa masu cutar kansa don karɓar wannan sabis ɗin, ko gwajin kwayar halitta don takaddun lasisi na cikin gida. Hanyar sadarwar Oncologist ta Duniya, a matsayin sanannen sanannen tsarin kula da masu cutar kansa, ya kasance cibiyar kula da cututtukan daji da sanannun masanan kansar suna aiki tare a kai a kai don tsara irin waɗannan manyan tarurruka na musayar ra'ayi tsakanin likitoci da haƙuri da kuma laccocin kimiyya masu mahimmanci don taimakawa marasa lafiya samun daidaito da bincikar iko da tsare-tsaren magani ta hanyar shawarwari na kwararru a cikin gida da waje, da inganta saurin warkarwa. Har ila yau, za mu ci gaba da himma don ci gaba da gabatar da manyan bayanai game da cutar kansar, fasahar kere-kere, masana, magunguna, gwajin asibiti, da sauransu, da kuma yin duk kokarin samar da karin marasa lafiya da ingantattun ayyukan cutar kansa.
Faxar Cancer a matsayin sanannen sanannen cutar daji ta gida da kuma neman magani da kuma dandamali na sabis, an himmatu don samar da sabis na rigakafin cutar kansa na farko ga marasa lafiyar kansar cikin gida, gami da sabuwar fasahar yaƙi da cutar kansa da mafi ƙwarewar masanan kansar, kafa mafi girma ƙari shawara da cibiyar ba da shawara a Indiya, da Haɗin kai tare da shahararrun cibiyoyin tuntuɓar tumo da ƙwararru a Amurka, China, Isra’ila, da Turai don zama mafi amintaccen ganewar asali da ƙwararren masani a duniya.
