Masu bincike a Memorial Sloan Kettering Cibiyar Ciwon daji da Cibiyar Fasaha ta Massachusetts sun kirkiro wani sabon tsari mai matakai uku da ke amfani da magungunan nukiliya don kai hari da kawar da cutar kansar launin fata. Masu binciken sun sami ƙimar warkarwa 100% a cikin ƙirar linzamin kwamfuta kuma ba su da wani tasiri mai guba da ya shafi magani. An buga rahoton binciken a cikin Jaridar Nuwamba na Magungunan Nukiliya.
Ya zuwa yanzu, radioimmunotherapy (farmaki da aka yi niyya) ta amfani da radionuclides da aka yi niyya don magance ƙaƙƙarfan ciwace-ciwacen yana da iyakance inganci. “Wannan sabon labari ne. Radiyon na biyu ba mai guba ba ne ga kyallen jikin mutum na yau da kullun wajen maganin ƙwayar tumor. ” Steven m. Larson da Dr. Sarah Cheal sun yi bayani, “Nasarar ƙirar ƙwayar ƙwayar linzamin kwamfuta ta samo asali ne daga ƙungiyar Ingancin ingantattun reagents, a gefe guda, ya samo asali ne daga rage hanyoyin aiwatarwa, gami da hanyar bincike na warkewa wanda za a iya sauƙaƙe sauyawa zuwa marasa lafiya. “Wannan hanyar tana amfani da magani ɗaya don tantancewa da magance cututtuka. Magungunan ya fara nemo kwayoyin cutar kansa sannan ya lalata su don kada a cutar da ƙwayoyin lafiya. Ta wannan hanyar, ana rage tasirin sakamako kuma ana inganta rayuwar mai haƙuri.
A cikin wannan binciken, an yi amfani da glycoprotein A33 (GPA33) don gane antigen tumor A33. An gwada DOTA-pretargeted radioimmunotherapy (PRIT) akan ƙirar linzamin kwamfuta. Don berayen gwajin da aka zaɓa ba da gangan ba, an yi amfani da hoton SPECT/CT don saka idanu kan martanin jiyya, kuma an ƙididdige adadin ƙwayar ƙwayar cuta. Berayen da aka gwada sun amsa da kyau. Babu wani daga cikin ɓerayen da aka tantance da ya nuna alamun ciwon daji a ƙarƙashin na'urar hangen nesa, kuma ba a ga wani gagarumin lahani na radiation a cikin mahimman gabobin da suka haɗa da maƙarƙashiya da koda.
Adadin warkarwa na 100% a cikin ƙirar linzamin kwamfuta shine abin marhabin, yana nuna cewa anti-GPA33-DOTA-PRIT zai zama ingantaccen tsarin radioimmunotherapy don GPA33-tabbataccen ciwon kansa.
Bisa ga CDC, ciwon daji na colorectal shine na uku mafi yawan cutar kansa da ke shafar maza da mata. A Amurka, akwai kusan sabbin maganganu 140,000 a kowace shekara da mutuwar 50,000.
Larson da Cheal sun yi imanin cewa idan an sami nasarar nasarar asibiti, wannan maganin na nukiliya za a iya fadada shi zuwa wasu cututtukan daji. An tsara tsarin azaman tsarin “toshe da wasa” wanda zai iya karɓar ƙwayoyin rigakafi daban -daban akan antigens tumor na ɗan adam, kuma bisa ƙa'idar aiki ya dace da duk ƙaƙƙarfan ƙwayar cuta da ruwa a jikin ɗan adam. Sun kara da cewa "fannin ilimin oncology, musamman munanan ciwace -ciwacen da suka hada da hanji, nono, pancreas, melanoma, huhu da esophagus, akwai matukar bukatar maganin cututtukan da suka ci gaba."
