A watan Disambar 2007, Malama 54, wacce ta yi fama da cutar ta rashin lafiya tsawon watanni 2, ta rage kiba, rashin cin abinci, kuma tana da ciwon kashi. A CT hoton kirji ya saukar da 9 cm x 5.8 cm x 7.2 cm "babba, an gyara shi, an inganta shi iri-iri" a cikin hagu zuwa ƙasan huhu. Bugu da kari, an sami wani karamin rauni mai kama da allura a cikin babba na hagu na sama.
Daga baya, biopsy ya tabbatar da cutarwa, matsakaiciyar rarrabewar huhu mai cutar sankarau. A CT dubawa ya nuna shigar tsokoki na bangon kirji kuma ya sami metastasized. Duban kashinta ba ya da kyau (babu metastases). Saboda haka, an gano ta da matakin T4N1M0-IIIb mara karamin tantanin halitta kwayar cutar huhu.
A cikin watanni 3, an bi da Ms. M tare da paclitaxel (260 MG) da carboplatin (415 MG) don hawan hawan 3. Wannan yana raguwa da tumo zuwa 7 cm x 6 cm x 5 cm. Daga baya, an yi maganin chemoradiotherapy a layi daya tare da hawan 2 na cisplatin (50 MG) da 60 Gy na radiation.
Watanni biyu bayan kammala aikin chemoradiotherapy, Ms. M ta sami labarin cewa akwai gwajin asibiti na huhu. maganin ciwon daji kuma sun yanke shawarar karɓar maganin CIMAvax bayan yin tunani game da shi.
80% na mutanen da suka karɓi maganin cyclophosphamide kafin allurar CIMAvax sun nuna wasu ayyukan anti-EGF. Alurar riga kafi a shafuka da yawa zai ƙara haɓaka tasiri.
Wani CT scan na farko ya nuna raunin 3 cm x 3 cm a cikin ƙananan lobe (Figure 1). Raunin lobe na hagu na hagu bai wuce santimita 1 a diamita ba, kuma zubar da jini a cikin gida ya kasance na biyu zuwa aikin rediyo.
Bayan watanni 3 na maganin CIMAvax na maganin rigakafin huhu, kumburin ya ragu zuwa 2 cm x 2.1 cm
Zuwa watanni 6 na jinya, ciwon ya yanke daga asalinsa da kashi 30% zuwa 1.5 cm x 2.3 cm kafin daidaitawa. A wannan lokacin, gurɓataccen muryarta na ci gaba da raguwa, kuma lymph nodes na gida sun zama ƙarami.
Yayin harbi 16 na farko, Madam M ba ta sami wata illa ba. A cikin 'yan mintuna kaɗan na allurar ta 17, jinƙan kugu ya "karu" kuma ana ɗauka amsar rigakafi mai alaƙa da Mataki na 3. Kwayar cututtukan sun lafa bayan minti 10 na magani tare da 10 mg na chlorpheniramine, 200 mg na hydrocortisone da 50 mg na tramadol.
Daga baya, ta yanke shawarar dakatar da magani tare da rigakafin CIMAvax. Anyi hoton CT na kirji watanni uku bayan dakatar da jiyya (watanni 18 bayan fara maganin CIMAvax). Watanni shida sun shude tun bayan binciken ta na karshe, kuma babu wani “gagarumin canji” a girman ƙari (Hoto na 3), kuma yanayinta ya kasance mai karko.
A bin bayan-28 na ƙarshe bayan dakatar da allurar rigakafin-FNM mata na cikin ƙoshin lafiya da lafiya da kwanciyar hankali. Matsayinta na ECOG ya kasance a 0 (mafi kyau). A wannan lokacin, ta rayu tsawon watanni 48 tun lokacin da aka gano ta kuma yanayinta ya daidaita.
Madam M's maganin huhu na huhu An amince da shi don tallatawa a Cuba a cikin 2008 don kulawa da mataki na IIIB-IV marasa ciwon ciwon huhu na huhu (NSCLC). Wannan shi ne rajista na farko na rigakafin warkewa a Cuba da kuma rajista na farko na rigakafin cutar kansar huhu a duniya.
