Ciwon daji na huhu yana daya daga cikin abubuwan da ke haifar da mutuwar dan Adam saboda ciwace-ciwacen daji, kuma yawan kamuwa da cutar da mace-mace ya kasance na daya a birane. Cutar sankarar mahaifa ita ce cutar kansar huhun ƙananan ƙwayoyin cuta (NSCLC), wanda ya kai kusan 85%. Yawancin marasa lafiya suna cikin tsaka-tsaki da ƙarshen matakan lokacin da aka gano su, kuma kashi 60 zuwa 80% na masu cutar kansar huhu sun rasa damar yin tiyata idan an gano su. A lokaci guda kuma, huhu shine na biyu mafi sauƙi na ƙwayar cuta mai ƙarfi na ciwace-ciwacen ƙwayoyi, sannan kuma hanta ya biyo baya. Ana amfani da maganin tiyata sau da yawa ga marasa lafiya tare da iyakacin adadin metastases. Tiyata na buƙatar cire wani ɓangare na ƙwayar huhu tare da aiki na yau da kullun. Sabili da haka, ana kuma buƙatar sabbin hanyoyin magani don maye gurbin tiyata.
In recent years, the minimally invasive radiofrequency ablation (RFA) technology has been used more and more as a minimally invasive treatment method in the treatment of primary / secondary lung tumors, and has made great progress, known as the treatment “Dinghaishen Needle” for kwayar cutar huhu.
Menene ablation na mitar rediyo?
Radiofrequency ablation consists of an electrode needle inserted into the tumo tissue and an electrode plate attached to the patient’s body to form a current loop. After the RF generator is turned on, high-frequency alternating current at the electrode tip is injected into the target tissue (Figure 2A), causing ions in the tissue to occur Shock, friction and heat generation will follow, causing cell death and coagulation necrosis in the target tissue around the electrode (Figure 2B). At the same time, the vascular tissue around the tumor will coagulate to form a reaction zone, preventing it from continuing to supply blood to the tumor and preventing tumor metastasis. Radio frequency waves can also cause tumor blood vessels to coagulate and reduce blood supply. At the same time, the ablated tumor tissue remains in the body. Due to its composition and structural changes, it can stimulate the body’s immunity and produce anti-tumor cytotoxic antibodies, and induce cytotoxic T cell immunity.
Wadanne cututtukan daji na huhu ne RFA ke amfani da su?
1. Used for cututtukan daji na kansa marasa kansar that cannot tolerate surgery. Tumor diameter ≤2cm, 78 ~ 96% of patients can achieve complete ablation; tumor diameter ≤3cm, 5-year survival rate exceeds 50%. The treatment effect is better for primary lung cancer with a diameter ≤5cm.
2. For the treatment of lung metastases. Studies have shown that lung metastases with a diameter ≤2-3 cm, patients with lung metastases receiving RFA treatment have a 3-year survival rate of 53.7% and a 4-year survival rate of 44.1%. As shown in Figure 3, a ciwon nono patient relapsed with a single left lung metastasis. After RFA treatment, the follow-up and follow-up for nearly 3 years showed a good quality of life and no distant recurrence.
3. Mara lafiya, mace, mai shekaru 48, tare da ciwon huhu guda ɗaya bayan tiyatar ciwon nono. Don kula da marasa lafiya masu ciwon huhu marasa ƙananan ƙwayoyin cuta, ciki har da masu hana tyrosine kinase (TKI), irin su Kemena, Iressa ko Trocaine bayan juriya na magungunan gida. Misali, maganin TKI ya zama zaɓi na farko na jiyya ga marasa lafiya tare da ci-gaba mai karɓar haɓakar haɓakar haɓakar epidermal (EGFR) a cikin ci gaban ciwon huhu mara ƙanƙanta. Cibiyar Nazarin Ciwon daji ta Shao Yifu tana amfani da fasahar RFA don maganin ciwon huhu mara karami da kuma daya daga cikin madadin hanyoyin magani don shawo kan juriyar TKI.
4: Mace mai shekaru 59 mai ci gaban ciwon huhu mara karama (EGFR) tare da metastasis na cikin huhu, watanni 15 bayan maganin TKI na baki, ciwon huhu na dama (Figure B) ya fi bayyane fiye da wanda ya gabata. (Hoto A) kamar yadda aka nuna ta kibiya Ƙara, ci gaban cuta; CT-gudanar da RFA magani na ƙananan ƙwayar huhu na dama (Figure C), wanda ya biyo bayan watanni 3 (Figure D), watanni 6 (Figure E) ya nuna kulawa mai kyau.
4. Haɗe da chemotherapy da radiotherapy. Chemotherapy da radiotherapy hade da radiofrequency ablation far ana amfani da metastatic hanta da kuma huhu ciwace-ciwacen daji. Haɗaɗɗen aikace-aikacen biyun na iya daidaita ƙarancin su da haɓaka inganci. Idan aka kwatanta da kowane yanayin jiyya guda ɗaya, yana tsawaita lokacin rayuwa na majiyyaci kuma yana inganta yanayin rayuwa.
The patient, a 58-year-old male, has colon cancer with multiple liver and lung metastases in the distance, making it difficult to operate and treat. Combined with chemotherapy and targeted drug therapy, especially combined with minimally invasive radiofrequency ablation technology, it successfully cured liver and lung metastases.
5. RFA can also be used for palliative treatment to relieve various discomfort symptoms of patients with advanced lung cancer.
6: Wani tsoho mai shekaru 88 da haihuwa mai fama da cutar kansar huhu ya sake dawowa tare da intra-pulmonary and pleural metastasis (wanda aka nuna a Figures A da B). Ciwo mai tsanani yana da wuya a yi barci. Ciwon mara lafiya ya sami sauƙi sosai bayan maganin RFA na ciwon huhu, kuma ingancin barci ya inganta sosai. Bayan shekara guda na bibiyar, majiyyaci gabaɗaya yana cikin yanayi mai kyau tare da bargawar ciwan huhu.
