Ciwon daji na pancreatic a halin yanzu yana ɗaya daga cikin mafi muni kuma mai jurewa chemotherapy. Kwanan nan, masu binciken ciwon daji a Ostiraliya sun kirkiro wata hanya mai ban sha'awa mai ban sha'awa wadda za ta inganta maganin ciwon daji na pancreatic.
This technology wraps drugs that can silence specific genes in nanoparticles and transport them to pancreatic tumors . It is expected to provide pancreatic cancer patients with alternatives to traditional treatments such as chemotherapy.
Experiments conducted on mice showed that the new nanomedicine method reduced tumo growth by 50% and also slowed the spread of pancreatic cancer.
Binciken da aka buga a cikin Biomacromolecules an gudanar da shi ne daga masana kimiyya daga Jami'ar New South Wales (UNSW). Yana kawo sabon fata ga mafi yawan marasa lafiyar cutar sankara wanda zai iya rayuwa tsawon watanni 3-6 bayan ganowar cutar.
Dokta Phoebe Phillips daga Cibiyar Nazarin Ciwon Kankara ta UNSW Roy (Cibiyar Nazarin Ciwon Kankara ta Lowy) ita ce babban mai kula da binciken. Ta ce a duk lokacin da takwarorinta likitoci suka sanar da masu ciwon daji na pancreatic, Ko da mafi kyawun maganin chemotherapy zai iya taimaka musu su tsawaita rayuwarsu na tsawon makonni 16, likitocin ba za su iya jurewa ba.
Dokta Phillips ya ce: “Babban dalilin da ya sa chemotherapy ba ya aiki shi ne, ciwace-ciwacen daji na pancreatic yana da nau’in tabo mai yawa, wanda zai iya kai kashi casa’in cikin 90 na ciwace-ciwacen da ake samu. Nama na tabo yana aiki azaman shinge na jiki wanda ke hana magunguna isa ga ƙari, yana haifar da ciwon daji na pancreatic. Kwayoyin suna jure wa chemotherapy. "
She explained: “Recently, we have discovered a key gene that promotes the growth, spread and resistance of pancreatic cancer-βIII-tubulin. Inhibiting this gene in mice not only reduced tumor growth by half, It also slows down the spread of cancer cells. “
Duk da haka, don murkushe wannan kwayar halitta ta asibiti, dole ne mutum ya shawo kan wahalar sarrafa magunguna: ketare tabo na ciwace-ciwacen daji. Don magance wannan matsala, masu bincike na Ostiraliya sun ƙera hanyar nano-likita, ƙananan ƙwayoyin RNA (ana iya fahimtar su a matsayin kwafin DNA na salula) wanda aka nannade a cikin nano-barbashi na ci gaba, waɗannan kwayoyin RNA sun kai ga ciwon daji bayan ya sami damar da yawa, hana βIII-tubulin gene.
Waɗannan masu binciken sun nuna yuwuwar sabbin nanoparticles a cikin mice. Nanoparticles ɗin su na iya isar da alluran warkewa na microRNA zuwa ciwace-ciwacen ƙwayar cuta a cikin mice a gaban ƙwayar tabo, kuma cikin nasarar hana βIII-tubulin.
"Mahimmancin fasahar mu na nanomedicine ita ce ana sa ran ta danne duk wani nau'in kwayar cutar ciwon daji, ko wani nau'in kwayoyin halittar da aka keɓance ta sirri" bisa la'akari da bayanin kwayar cutar tumor mara lafiya." Dr. Phillips ya ce.
"Wannan nasarar da aka samu za ta taimaka wa mutane wajen samar da sabbin magunguna game da wannan cutar ta kansar da kuma inganta tasirin hanyoyin da ake amfani da ita don inganta rayuwar masu cutar kansar."
