Ososayensi babika ukuthi umthamo omncane wansuku zonke we-Viagra unganciphisa kakhulu ingozi yomdlavuza obala kumamodeli wezilwane, okuyimbangela yesithathu ehamba phambili yokufa komdlavuza.
UDkt.Darren D. Browning, umcwaningi womdlavuza eGeorgia Cancer Center kanye noMnyango Wezinto Eziphilayo kanye neMelecular Biology, uthe iViagra inganciphisa ukwakheka kwama-polyps ngesigamu. Ama-polyps ayiqoqo lamaqoqo wamathumbu angaphakathi angajwayelekile futhi ajwayele ukuba ne-asymptomatic, kepha ama-polyps anethuba lokuba ngumdlavuza.
I-Viagra ingavimbela i-enzyme eyenzeka ngokwemvelo i-PDE5 kumaseli e-colon kanye nezinye izicubu ezijikelezayo ze-GMP ezibolayo, ngakho-ke ingasetshenziswa ukunciphisa ukwanda kwamangqamuzana futhi ithuthukise ukuhlukaniswa kwamaseli, njengamaseli e-goblet afihla amafinyila avikelayo. Ucwaningo luthole ukuthi ukukhomba ukujikeleza kokusayina kwe-GMP kubonakala kuyisu elihle lokuvimbela iziguli ezisengozini enkulu.
The study found that placing Viagra in the drinking water of mice reduced polyps in the mouse model, and the mice had genetic mutations in adenomatous polyposis coli (APC). Like these mice, people with mutations in the APC gene can develop into hundreds or thousands of polyps in the colon and rectum, and ultimately eventually cause umdlavuza colorectal. At the same time, giving Viagra to young mice can reduce the number of tumors in these animals by half.
Uveze ukuthi iViagra isineminyaka eminingi isemakethe futhi yaziwa ngamandla ayo okuphumuza amangqamuzana emisipha abushelelezi emithanjeni yegazi. Isetshenziswa kubantu abanemithamo eminingi kanye namaqembu eminyaka yobudala, kusukela ezigulini ezinomfutho wegazi ophakeme ngaphambi kwesikhathi ukuya kubantu asebekhulile abanokungasebenzi kahle kwe-erectile. UDkt. Browning uthe isinyathelo esilandelayo kufanele sifake ukuhlolwa kwezidakamizwa kubantu abasengozini enkulu yomdlavuza wekoloni, njengalabo abanomlando oqinile womndeni, ama-polyps amaningi, nokuvuvukala kwamathumbu okungapheli okufana ne-colitis. Uma ukuhlolwa kuzuza imiphumela eyanelisayo, i-Viagra izovuselela izinkomba zokuvimbela umdlavuza.
