Funda umhlahlandlela wethu ukuze ufunde mayelana nezinkomba ezithule ze-myeloma eminingi. Funda ukuzibona kusenesikhathi, ukuze ukwazi ukwenza izinqumo ezihlakaniphile zempilo yakho. Ungazinaki izimpawu eziyisixwayiso, zinike amandla ngolwazi futhi ulawule inhlalakahle yakho namuhla!
Sawubona, ukulwa nomdlavuza! Le bhulogi ihlose ukukunikeza ukuqonda okungcono kwezimpawu nezimpawu ze-myeloma, umdlavuza odinga ukunakwa ngokushesha. Impilo yakho iyimpahla ebalulekile, nokuqaphela izimpawu zokuthi i-myeloma eminingi kungenza umehluko. Isayensi yethu yezokwelapha manje isithuthuke kakhulu ekunakekelweni komdlavuza ngokwethula ukwelashwa kwe-t cell therapy eNdiya. Uma ufuna ukwazi i izindleko zokwelashwa kwe-CAR T cell eNdiya, ungaxhumana nathi. Singakusiza ukuthi uxhumane nochwepheshe bomdlavuza abangcono kakhulu ukuze uthole ukunakekelwa okuphuthumayo, kanye nekusasa eligcwele amandla nethemba.
Iyini I-Multiple Myeloma Disease?
I-Myeloma eminingi ithinta amaseli e-plasma ayingxenye ebalulekile yamasosha omzimba. Ngokuvamile kuvela emnkantsheni wamathambo, kube nomthelela ekukhiqizeni amangqamuzana egazi avamile. Noma ubani angaba sengozini, kodwa izici ezithile zingase zandise ingozi. Lamangqamuzana anomdlavuza akhiqiza amaprotheni angavamile angaholela ezinkingeni ezinjengobuthakathaka bamathambo, ukuntuleka kwegazi emzimbeni, izinkinga zezinso, nokukhubazeka kwamasosha omzimba. Imbangela eqondile ye-myeloma eminingi ayiqondwa kahle, kodwa izici ezithile zobungozi, njengeminyaka yobudala, umlando womndeni, nokuchayeka kumakhemikhali athile, zingase zibe nomthelela ekuthuthukisweni kwayo. Kodwa-ke, ukukhomba izimpawu ze-myeloma eminingi kanye nokuthola usizo lwezokwelapha ngokushesha kuyadingeka ukuze kuphumelele ukwelashwa kwe-myeloma eminingi eNdiya.
Funda Manje: I-Immunotherapy Ingakusiza Ukunqoba Impi Ngokumelene Ne-Myeloma Eningi!
Izimbangela Nezici Zengozi Ye-Myeloma Eningi
Izici eziningana zingandisa ingozi yokuthuthukisa i-myeloma eminingi.
Izimpawu ze-myeloma eminingi kubantu abadala zivame kakhulu. Isilinganiso seminyaka yokuxilongwa sisondele ku-70. Kuphela ama-2% ezigameko ezenzeka kubantu abadala abangaphansi kweminyaka engama-40.
Abantu abaye bachayeka emisebeni, izibulala-zinambuzane, noma amakhemikhali asetshenziswa ekwenzeni irabha bangase babe sengozini enkulu. Imisebenzi ehlanganisa izinto zokhuni, enjengokubaza nefenisha ibhekene nengozi eyengeziwe.
Abantu abaye baba ne-plasmacytoma eyedwa yethambo banamathuba amaningi okuthuthukisa i-myeloma eminingi.
Ukuba khona kwenani elincane le-M protein egazini kwandisa ingozi ngo-1% kuya ku-2% ngonyaka.
Ucansi: I-Myeloma ivela kakhulu emadodeni kunabesifazane.
Funda kabanzi: Ukukhethwa Kwesiguli Kokwelashwa Kwe-CAR T: Umhlahlandlela Ophelele
Iqala Kanjani I-Myeloma Eningi?
I-Myeloma eminingi iqala lapho kukhona ukukhula okungavamile nokungalawuleki kwamaseli e-plasma emnkantsheni wamathambo. Inqubo ngokuvamile ihilela izigaba ezimbalwa:
Amaseli e-Plasma Ajwayelekile:
Amaseli e-plasma ayingxenye yamasosha omzimba kumuntu ophile kahle futhi akha amasosha omzimba (ama-immunoglobulins) ukuze alwe nezifo.
I-Monoclonal Gammopathy Yokubaluleka Okunganqunyelwe (MGUS):
Abanye abantu bangase babe ne-MGUS ngaphambi kokuthuthukisa i-myeloma eminingi. Ku-MGUS, kuneprotheyini engavamile (M protein) ekhona egazini, kodwa azikho ezinye izimpawu noma izimpawu. I-MGUS yandisa ingozi yokuthuthukisa i-myeloma eminingi ngokuhamba kwesikhathi.
I-Myeloma eminingi ebhemayo:
Lesi sigaba sibonakala ngamazinga aphezulu amaseli e-plasma angavamile kune-MGUS, kodwa azikho izimpawu ezithile ze-myeloma ebhemayo. Kodwa-ke, kubeka engcupheni enkulu yokuqhubekela phambili ku-myeloma eminingi esebenzayo.
I-Active Multiple Myeloma:
Kulesi sigaba, kunokwenyuka okukhulu kwamaseli e-plasma angajwayelekile, aminyanisa amangqamuzana egazi anempilo emnkantsheni. Lawa mangqamuzana anomdlavuza angakwazi futhi ukukhiqiza amaprotheni angavamile, okuholela ezinkingeni ezihlukahlukene ezinjengobuthakathaka bamathambo, i-anemia, izinkinga zezinso, nokukhubazeka kwamasosha omzimba.
Thola imininingwane: Ulwazi Olujulile Ngenqubo Yokwelapha Amaseli e-CAR T - CancerFax
Yazi Izimpawu Nezimpawu Ze-Myeloma
Okulandelayo yizimpawu eziyisixwayiso ze-myeloma eminingi okungafanele neze uzigweme -
Ukukhathala
Kungani: I-Myeloma ingase ibangele umzimba wakho ukuthi udale izinto ezingavamile, zenze ukhathale.
Umthelela: Kuthinta amazinga akho wamandla nemisebenzi yansuku zonke. Lezi yizimpawu ezivame kakhulu ze-myeloma eminingi.
Ubuhlungu Bethambo:
Kuphi: Ngokuvamile kungemuva noma ezimbanjeni.
Imbangela: Amaseli e-Myeloma akhula emathanjeni, abangela ukulimala kwamathambo.
Nini: Ubuhlungu bukhulu kakhulu lapho uhamba nasebusuku.
Ukuba mfishane:
Nini: Lesi ngesinye sezimpawu ezijwayelekile zesigaba sokuphela kwe-myeloma.
Kungani: Amathambo acindezelwe emgogodleni angakwenza ulahlekelwe ngamasentimitha ubude.
Izinkinga Zesistimu Yezinzwa:
Umthelela: Ubuhlungu, ukuba ndikindiki, ubuthakathaka.
Kungani: Amathambo awile ecindezela umgogodla noma imizwa.
Izinkinga zezinso:
Izimpawu: Ukulunywa, ubuthakathaka, inkinga yokulala, noshintsho ekuchameni. Lezi ezinye izimpawu ezivamile eziningi ze-myeloma zesigaba sokuphela.
Imbangela: Amaprotheni e-Myeloma angalimaza izinso zakho.
Amazinga aphezulu eCalcium (Hypercalcemia):
Izimpawu: Ukozela, ukuqunjelwa, nokukhubazeka kwezinso yizo zonke izimpawu ezibonakalayo ze-myeloma.
Kwenzeka: Lapho amathambo akho ephuka ngokweqile.
Ukuzizwa Ukungalingani:
Ukuncipha kwesisindo, isicanucanu, ukoma, ubuthakathaka bemisipha, nokudideka konke kuyizimpawu zomdlavuza we-myeloma eminingi.
Izizathu: Izinkinga zezinso, i-calcium ephezulu, noma ezinye izinkinga zegazi.
Ukugula Kaningi:
Ingozi: Ukutheleleka, ikakhulukazi emaphashini akho.
Kungani: I-Myeloma yenza buthaka amasosha akho omzimba.
Izinkinga Ezihlobene Negazi:
Izimpawu: Amahlule, ukopha, imihuzuko.
Imbangela: I-Myeloma ithinta igazi lakho.
Yikuphi Ukwelashwa Okungcono Kakhulu Kwe-Myeloma?
Ukwelashwa okungcono kakhulu kwe-myeloma eminingi kuncike ezintweni ezihlukahlukene, okuhlanganisa isigaba sesifo, impilo yonke yesiguli, nezici ezithile zamangqamuzana omdlavuza. Enye indlela yokwelashwa ethembisayo nentsha ukwelapha ngokwelashwa kwamaseli e-CAR T eNdiya. Ukwelashwa kwe-CAR T cell kuhilela ukuguqula amaseli omzimba esiguli ukuze abone futhi ahlasele amangqamuzana omdlavuza ngempumelelo kakhudlwana. Ukwelashwa kunamandla okukhomba nokususa amaseli e-plasma anomdlavuza, okuvumela isu lokwelapha elenzelwe umuntu siqu neligxile kakhulu. Ukwelashwa kwe-CAR T cell kukhombisa isithembiso njengendlela yokuguqula ekwelapheni i-myeloma eminingi e-India, okuletha ithemba elisha kulabo abathintwe yilesi sifo esiyinkimbinkimbi nesinzima. Ngakho-ke, uma ubona noma yiziphi izimpawu ze-myeloma eminingi okukhulunywe ngenhla, ngokushesha thintana nochwepheshe ongcono kakhulu ukuze ululame ngokushesha.
Qaphela - Ulwazi olunikezwe kule bhulogi luhloselwe ulwazi olujwayelekile kuphela. Njalo funa iseluleko somhlinzeki wezempilo oqeqeshiwe nganoma yimiphi imibuzo ongase ube nayo mayelana nezimpawu ze-myeloma eminingi.
Imibuzo Evame Ukubuzwa Ehlobene Nezimpawu Ze-Myeloma Eningi
Ikuphi Ukwelashwa Okungcono Kakhulu Kwe-Myeloma Eningi Ezigulini Ezikhulile?
Ukwelashwa okungcono kakhulu kwe-myeloma eminingi ezigulini esezikhulile kuncike ezicini ezihlukahlukene futhi kunqunywa isigaba sesifo, kanye nesimo sezempilo somuntu ngamunye.
Yiziphi Izimpawu Zesigaba Sakamuva Se-Myeloma Eningi?
Izimpawu ze-myeloma eziningi zesigaba sekwephuzile zingabandakanya ubuhlungu obukhulu bethambo, ukukhathala, izinkinga zezinso, i-anemia, kanye nezifo ezivamile.
Iyini Isilinganiso Sokuphila Kweziguli Eziningi Ze-Myeloma?
Isilinganiso sokuphila kweziguli eziningi ze-myeloma siyahlukahluka, kodwa ukuthuthuka ekwelashweni kuye kwaba nemiphumela engcono, futhi abantu abaningi bangaphila iminyaka engaphezu kwengu-5-10 ngokunakekelwa okufanele.
Yiziphi Izimbangela Eziyinhloko Ze-Myeloma Eningi?
Izimbangela eziyinhloko ze-myeloma eminingi azaziwa, nokho, ubudala, uhlanga, izakhi zofuzo, kanye nokuchayeka ezintweni ezithile kungase kube nendima ekuthuthukisweni kwayo.
Yiziphi Izimpawu Zomlomo Eziningi ze-Myeloma?
Izimpawu eziningi zomlomo we-myeloma zingase zihlanganise ubuhlungu bomhlathi, amazinyo axegayo, nokuba ndikindiki ngenxa yethonya lesifo kugebhezi namathambo obuso.
Yiziphi Izimpawu Zokuqala Ze-Myeloma Eningi?
Izimpawu nezimpawu ze-myeloma eminingi zihlanganisa ubuhlungu bamathambo, ukukhathala, kanye nezifo ezivamile.
