Umdlavuza we-Pancreatic
Umdlavuza we-pancreatic, owaziwa nangokuthi inkosi yomdlavuza, ungesinye sezimila eziyingozi ezijwayelekile zohlelo lokugaya ukudla. Eminyakeni yamuva nje, womabili amazwe athuthukile nasathuthuka, izehlakalo nokufa komdlavuza we-pancreatic kubonise umkhuba okhuphukayo. Umdlavuza we-pancreatic wuhlobo olubi kakhulu lomdlavuza onezinga lokusinda eliphansi kakhulu.
Umdlavuza we-pancreatic one-malignancy ephezulu kanye ne-prognosis embi
Ukwelashwa ngokuhlinzwa kungase kwandise isikhathi sokusinda. Nakuba ukwelashwa okuyinhloko komdlavuza we-pancreatic kusahlinzwa, izinga lokusinda leminyaka engu-5 lomdlavuza we-pancreatic ngemva kokuhlinzwa liphansi kakhulu kuzo zonke izifo ezimbi zesisu, ngaphansi kwe-10%. Iziguli eziningi ezingakwazi ukuhlinzwa ziyafa phakathi nezinyanga eziyisithupha, ngakho ukubikezelwa komdlavuza we-pancreatic kubi kakhulu.
Ezigulini ezinomdlavuza we-pancreatic ezingakwazi ukuhlinzwa, ukuthola ukwelashwa ngasikhathi sinye noma ukwelashwa ngamakhemikhali kuyindlela eyinhloko yokwelashwa, futhi ukwelapha nge-chemoradiation ngesikhathi esisodwa kuwukwelashwa okubaluleke kakhulu ezigulini ezinomdlavuza we-pancreatic othuthukile. Ezigulini ezingcolile, i-radiotherapy kanye nokwelashwa ngamakhemikhali ngasikhathi sinye kungavala ukushiyeka kokuhlinzwa. Kodwa-ke, kwaziwa kahle ukuthi kungakhathaliseki ukuthi i-radiotherapy noma i-chemotherapy, imiphumela yemiphumela emibi ingumthwalo omkhulu emzimbeni weziguli ezinomdlavuza, futhi ngisho nangaphezulu ayikwazi ukubekezelela nokuyeka ukwelashwa.
I-Proton therapy iyikhandidethi elingcono kakhulu lomdlavuza we-pancreatic
Selokhu kwazalwa i-proton radiation therapy, ibilokhu ithola ukunakwa kwemboni ngokunemba kwayo okuphezulu nokuvikelwa kwezitho ezizungezile. Ngokunaka okwandayo kwe-proton radiotherapy, ukusetshenziswa kwe-proton radiation therapy yomdlavuza we-pancreatic nakho sekuphenduke inketho ezigulini ezinomdlavuza we-pancreatic Enye yezindlela zokwelapha ezingahlinzeki.
Nakuba eminye imidlavuza ye-pancreatic ingelapheka kahle ngokuhlinzwa, ngokwelashwa ngamakhemikhali nange-radiotherapy, ngenxa yokuthi izitho eziseduze kwama-pancreas-kuhlanganise nomgudu wamathumbu, izinso, nomgogodla-azikwazi ukumelana nemithamo ephezulu yemisebe, ukwelashwa ngemisebe yendabuko ngokuvamile kubangela izinkinga ezihlukahlukene Iziguli eziningi zihlushwa izifo eziningi. imiphumela emibi futhi uhlupheke kabuhlungu. I-Proton radiation therapy ingagxilisa imisebe eminingi endaweni yesimila, igweme izicubu ezinempilo ezungeze isimila, ngaleyo ndlela kwehlise imiphumela emibi ehlobene nokwelashwa. Ngasikhathi sinye, ngenxa yokuthi i-proton ikhipha umthamo omkhulu wemisebe endaweni yesimila, ingabulala amangqamuzana omdlavuza ngangokunokwenzeka.
Amacala aphumelele wokwelashwa kwe-proton ezigulini ezinomdlavuza we-pancreatic ongasebenzi
Isiguli: Owesilisa, oneminyaka engama-51 ubudala
Isikhalazo esikhulu: ukuhlanza ngokuphatheka kabi kwesisu isikhathi esingaphezu kwesigamu sonyaka
Umlando: Ukuhlanza okuhambisana nokungakhululeki kwesisu nokungakhululeki. Isibhedlela sendawo saba ngcono futhi saphinde sabuyela emuva ngemva kokwelashwa okunezimpawu. I-laparotomy yenziwa esibhedlela esiseningizimu. Ngesikhathi sokuhlinzwa, kwavela ingwegwe ye-pancreatic futhi kwatholakala isisindo esingu-4 * 3 * 3 cm. Umthambo wamathumbu wangenwa eduze komthambo we-mesenteric. I-Biopsy yabonisa ukuthi i-metastatic adenocarcinoma
Ukuhlolwa kwe-CT kubonise ukuthi inqubo engasetshenzisiwe yekhanda le-pancreatic yandisiwe, imiphetho yayingajwayelekile futhi ilukhuni, futhi ukuminyana kwakusefana. I-bile duct evamile ngokusobala yayicindezelwe ngemuva, okwathuthukisa imithambo yegazi eminyene eduze kwesithwebuli. Ithunzi, elihlanganiswe ngokwengxenye, eliqiniswe kancane, izithunzi zokuminyana okufana namanzi zibonakala endaweni yamathumbu e-peritoneal, ngemuva kwe-fundus yesisu, ezungeze isibindi nobende.
Ukuxilongwa nokwelashwa: ngemuva kokungeniswa, thuthukisa zonke izivivinyo ezisizayo, ngemuva kokuxilongwa okuqondile, yenza ukwelashwa ngemisebe ye-proton, unikeze amanyikwe + izilonda ze-lymph node ze-retroperitoneal.
I-DT: 48CGE / 12f
Umphumela wokwelapha: Ukulandelela ngemva kweminyaka emithathu, i-ascites yesiguli yanyamalala, isimo esivamile sihle, akukho ukusabela okubi okusobala okubonakalayo; isimila siyancipha kakhulu futhi silawulwa ngokuphumelelayo.
Isithombe ngaphambi kokwelashwa kwe-proton: isimila sitholakala eduze kwe-aorta yesisu enobuningi obungalingani
Ukusatshalaliswa komthamo we-proton therapy kunezinzuzo ezisobala, futhi kunomphumela omuhle wokuvikela entanjeni yomgogodla, izinso kanye nezicubu nezitho eziseduze ezijwayelekile.
Ukuhlaziywa kwecala le-Proton therapy
Ukwelashwa kweProton kunokusabalalisa umthamo womzimba ophakeme kakhulu. Ihlukile kwe-radiotherapy yendabuko, ukwelashwa kwe-proton kungakha indawo “yokuqhuma okuhlosiwe” enethamo eliphezulu endaweni yesimila, futhi ngasikhathi sinye, izicubu ezijwayelekile ezizungeze isimila azivezwa emisebeni emincane noma emincane, ngakho-ke kunganciphisa imiphumela. ye-radiotherapy noma i-chemotherapy ehlanganisiwe kanye ne-radiotherapy Imiphumela engathandeki yangaphambi kwesikhathi nangemuva kwepheshana lamathumbu, isibindi, izinso nomgogodla ingakhuphula umthamo wemisebe yesimila ukuze kuzuzwe izinga eliphezulu lokulawula isimila.
Yiziphi izimila okufanele ukwelashwa kwe-proton?
Ukusetshenziswa kwe-proton therapy kubanzi kakhulu. Ngaphezu komdlavuza we-pancreatic, ukwelashwa kwe-proton kunomthelela omuhle kumdlavuza ojwayelekile njengomdlavuza wesibindi, umdlavuza wamaphaphu, umdlavuza wendlala yesinye, umdlavuza webele kanye nomdlavuza wesibeletho. Umdlavuza we-nasopharyngeal, izimila zamehlo), izimila zezingane kanye neminye imiphumela ingcono. Ukwelashwa kwe-Proton kuzwela kakhulu ekwelapheni umdlavuza ezinganeni nasebancane, futhi kungathuthukisa ngempumelelo izinga lempilo nokuphila kwezingane ngemuva kokwelashwa. Imiphumela engemihle mincane kakhulu, engavimbela ngempumelelo ukukhula nokuthuthukiswa kwezingane ekulimazeni ukwelashwa komdlavuza.
Iziguli ezinomdlavuza zingayithatha kanjani i-proton therapy?
Okuqukethwe kwale akhawunti yomphakathi okokuxhumana nokubhekisela kuphela, hhayi njengesisekelo sokuxilongwa nokwelashwa, futhi yonke imiphumela ebangelwa izenzo ezenziwe ngokuvumelana nalesi sihloko iwumthwalo wemfanelo womdlali kuphela. Ngemibuzo yezokwelapha echwepheshile, sicela uthintane nesikhungo sezokwelapha esichwepheshile.
