Isitatimende sephephandaba
Febhuwari 2023: – I-Kite, Inkampani yaseGileyadi (NASDAQ: GILD), namuhla imemezele ukuphothulwa komsebenzi owamenyezelwa ngaphambilini wokuthola i-Tmunity Therapeutics (Tmunity), okuyisiteji somtholampilo, inkampani yangasese ye-biotech egxile esizukulwaneni esilandelayo se-CAR T-therapies kanye nobuchwepheshe.
Ukutholwa kwe-Tmunity kuhambisana namakhono e-Kite akhona okucwaninga ngokwelashwa kwamaseli angaphakathi ngokwengeza izimpahla zamapayipi ezengeziwe, amakhono enkundla, kanye nesivumelwano samasu socwaningo neselayisensi neNyuvesi yasePennsylvania (Penn). Izohlinzeka iKite ngokufinyelela ezinhlelweni zangaphambi komtholampilo nezomtholampilo, okuhlanganisa inkundla yobuchwepheshe 'yezikhali' ze-CAR T, okungenzeka isetshenziswe ezinhlobonhlobo zama-CAR T ukuze kuthuthukiswe umsebenzi wokulwa nesimila, kanye nezinqubo zokukhiqiza ngokushesha. Ukwengeza, njengengxenye yokutholwa, abasunguli be-Tmunity, abasasele ezindimeni zabo e-Penn, bazophinde banikeze izinsizakalo zokubonisana ku-Kite njengabeluleki abakhulu besayensi.
I-University of Pennsylvania Relationship
UCarl June waseNyuvesi yasePennsylvania, uBruce Levine, uJames Riley, u-Anne Chew babengabanikazi bokulingana ngabanye e-Tmunity futhi manje sebekhokhelwa abeluleki besayensi kuKite. U-Penn naye ubengumnikazi wezabelo e-Tmunity. U-Penn uthole uxhaso lwezimali locwaningo oluxhaswe kwa-Tmunity, futhi manje usezothola uxhaso lwezimali locwaningo oluxhaswe kwa-Kite ngemva kokuvalwa kwanamuhla. Njengabasunguli bobunye ubuchwepheshe obunelayisensi, uDkt. U-June, u-Levine, u-Riley, no-Chew, kanye no-Penn, bangathola izinzuzo zezezimali ezengeziwe ngaphansi kwelayisensi esikhathini esizayo.
Mayelana neKite
I-Kite, Inkampani yaseGileyadi, yinkampani yomhlaba wonke ye-biopharmaceutical ezinze e-Santa Monica, eCalifornia, egxile ekwelashweni kwamaseli ukwelapha kanye nokwelapha umdlavuza okungenzeka. Njengomholi we-cell therapy emhlabeni jikelele, u-Kite welapha iziguli eziningi Ukwelashwa kwe-CAR T-cell than any other company. Kite has the largest in-house cell therapy manufacturing network in the world, spanning process development, vector manufacturing, isivivinyo somtholampilo supply, and commercial product manufacturing.
Mayelana neSayensi yaseGileyadi
I-Gilead Sciences, Inc. yinkampani ye-biopharmaceutical ephishekele futhi yazuza impumelelo kwezokwelapha iminyaka engaphezu kwamashumi amathathu, ngenhloso yokudala umhlaba onempilo kubo bonke abantu. Le nkampani izibophezele ekuthuthukiseni imithi emisha yokuvimbela nokwelapha izifo ezisongela ukuphila, okuhlanganisa i-HIV, i-viral hepatitis kanye nomdlavuza. IGileyadi isebenza emazweni angaphezu kuka-35 emhlabeni wonke, inendlunkulu eFoster City, eCalifornia. ISayensi yaseGileyadi yathola iKite ngo-2017.
Izitatimende Ezibheke Phambili ZaseGileyadi
Lokhu kukhululwa kwabezindaba kufaka phakathi "izitatimende ezibheke phambili" ngaphakathi kwencazelo ye-Private Securities Litigation Reform Act of 1995 engaphansi kwezingozi, ukungaqiniseki, nezinye izici, okuhlanganisa ingozi yokuthi i-Gilead neKite ingase ingaziboni izinzuzo ezilindelekile zalo msebenzi. , okuhlanganisa ikhono leKite lokuqhubekisela phambili izimpahla ezitholwe kwa-Tmunity ngocwaningo lwamacebo nesivumelwano selayisensi noPenn noma ngenye indlela; ubunzima noma izindleko ebezingalindelekile mayelana nokutholwa kanye nokuhlanganiswa; umphumela ongase ube khona wanoma yikuphi osekushiwo emalini eholwa iGileyadi neKite; kanye nanoma yikuphi ukucatshangelwa okuhambisana nanoma yikuphi kwalokhu osekushiwo. Lezi nezinye izingozi, ukungaqiniseki, nezinye izici zichazwe ngokuningiliziwe kuMbiko Wekota WaseGileyadi Wefomu 10-Q wekota ephele ngo-September 30, 2022, njengoba ufakwe kuKhomishini Yezimboni Nezokuhwebelana YaseMelika. Lezi zingozi, ukungaqiniseki, nezinye izici zingabangela imiphumela yangempela ukuthi ihluke kakhulu kulezo okubhekiselwe kuzo ezitatimendeni ezibheke phambili. Zonke izitatimende ngaphandle kwezitatimende zamaqiniso omlando ziyizitatimende ezingathathwa njengezibikezelo ezibheke phambili. Umfundi uyaxwayiswa ukuthi noma yiziphi izitatimende ezinjalo ezibheke phambili azisona isiqinisekiso sokusebenza kwesikhathi esizayo futhi zibandakanya ubungozi nokungaqiniseki, futhi uyaxwayiswa ukuthi angabeki ukuthembela ngokungafanele kulezi zitatimende ezibheke phambili. Zonke izitatimende ezibheke phambili zisekelwe olwazini olutholakala eGileyadi neKite njengamanje, futhi iGileyadi neKite azibophezeleki futhi azinanjongo yokuvuselela noma yiziphi izitatimende ezibheke phambili.
