UMingyang Song waseHarvard Medical School kanye neMassachusetts General Hospital ibike ukuthi ngemva kokuxilongwa komdlavuza we-colorectal non-metastatic, ukudla i-fiber eyengeziwe kuzonciphisa ukufa okuqondile kanye nokufa okuphelele komdlavuza we-colorectal. Ukwanda kokudla kwe-fiber ngemuva kokuxilongwa kungazizuzisa iziguli ezinomdlavuza omhlophe. (JAMA Oncol. Uhlobo oluku-inthanethi ngoNovemba 2, 2017).
Although it has been shown that high dietary fiber intake reduces the risk of colorectal cancer, it is not clear whether high fiber intake will benefit colorectal abasinde emdlavuzeni.
Ukuhlola ubudlelwano phakathi kokudla kwe-fiber kanye nokufa, lolu cwaningo lubandakanye iziguli eziyi-1575 ezinomdlavuza wesigaba I kuya ku-III wemibala emikhulu evela kumaqembu amabili angaba khona; ngemuva kokulungiswa kokunye ukubikezela okusinda komdlavuza, ukucaciswa komdlavuza obala ngamanqamu kwanqunywa Ukufa nokufa okuphelele.
Phakathi kwezinyanga eziyi-6 neminyaka eyi-4 ngemuva kokutholakala komdlavuza obucayi, abacwaningi basebenzise uhlu lwemibuzo oluqinisekisiwe ngobuningi bokudla ukuze kuhlolwe inani lokudla kwe-fiber, inani le-fiber evela emithonjeni ehlukene kanye nenani likakolweni ophelele.
Among the 1575 participants, 963 (61.1%) were women; the average age was 68.6 years. With a median follow-up of 8 years, 773 patients died, of which 174 died from colorectal cancer. A high total fiber intake after diagnosis is associated with a lower mortality rate. For every 5g increase in daily intake, the multivariable HR for colorectal cancer specific mortality and all-cause mortality were 0.78 (95% CI 0.65 ~ 0.93; P = 0.006) and 0.86 (95% CI 0.79 ~ 0.93) P <0 .001). According to fiber sources, cereal fiber can reduce colorectal cancer-specific mortality (for every 5 g / d increase in intake, HR = 0.67, 95% CI 0.50 ~ 0.90; P = 0.007) and all-cause mortality (HR = 0.78, 95% CI 0.68 ~ 0.90; P <0.001); vegetable fiber can reduce all-cause mortality (HR = 0.83, 95% CI 0.72 ~ 0.96; P = 0.009), but it does not reduce colorectal cancer-specific mortality (HR = 0.82, 95% CI 0.60 ~ 1.13; P = 0.22); No correlation was found between fruit fiber and mortality. Ingestion of whole wheat food can reduce the specific mortality of colorectal cancer (for every 20 g / d increase in intake, HR = 0.72, 95% CI 0.59 ~ 0.88; P = 0.002), but the correlation It will weaken after entry (HR = 0.77, 95% CI 0.62 ~ 0.96; P = 0.02).
