Abacwaningi baseMayo Clinic e-United States babike emhlanganweni we-2018 Digestive Disease Week ukuthi benze ucwaningo lwegazi lwe-DNA olungakhomba kahle u-95% wezigameko zomdlavuza wesibindi ezivamile.
Njengamanje, ukutholwa kwe-ultrasound kanye ne-alpha-fetoprotein kusetshenziswa emtholampilo ukuthola umdlavuza wesibindi. Lokhu kutholakala kwamalunga akuzwela kakhulu kumdlavuza wesibindi owelaphekayo. Ucwaningo lwakamuva lubonise ukuthi lokhu kuhlolwa okuhlanganisiwe kungathola u-63% wabantu abanomdlavuza wesibindi. Lokhu kuhlola akuzweli kakhulu kumdlavuza wesibindi owelaphekayo, futhi abantu abaningi abadinga ukuhlolwa akulula ukuthola lolu hlobo lokuhlola ngokuhlanganyela noma abakwazi ukuhlolwa njalo ngokwanele ukuze bathole ukutholakala okuphumelelayo.
Abacwaningi basebenzise izimpawu zomdlavuza wesibindi ezaziwayo ezingavamile ze-DNA. Ocwaningweni lweziguli ezingama-244, amasampula egazi amaningi avela ezigulini ezinomdlavuza wesibindi oyinhloko anezimpawu ze-DNA ezingavamile. Izimpawu ezingavamile zingakhomba ngokunembile u-95% womdlavuza wesibindi. Iziguli, u-93% wazo usesigabeni eselaphekayo. Lezi zimpawu azitholakali kubantu abanempilo kanye neziguli ezine-cirrhosis.
Abacwaningi baveze ukuthi into ethokozisayo wukuthi izimpawu ze-DNA zikwazi ukubona iziguli ezingaphezu kuka-90% ezinomdlavuza wesibindi owelapheka, okuyinzuzo enkulu yalokhu kuhlolwa nokuhlolwa kwamanje. Isinyathelo esilandelayo siwukuqinisekisa lokhu kuhlolwa kwegazi umaka eqenjini elikhulu lesampula.
Abacwaningi bazinikele ekuhloleni ama-biomarker ezinhlobo eziyi-16 zamathumba, okuhloswe ngawo ukwenza izivivinyo ezimbili ezinkulu, okungukuthi, ukuhlolwa kwendle kusetshenziselwa izimila zesisu, futhi ukuhlolwa kwegazi kusetshenziselwa ezinye izimila ezihlanganisa umdlavuza wesibindi nomdlavuza wamaphaphu.
