Ucwaningo lwaseSweden lubonise ukuthi ukugoma ikholera ngemva kokuxilongwa komdlavuza we-colorectal kunganciphisa ingozi yokufa okuhlobene nomdlavuza we-colorectal kanye nokufa okuyimbangela. (Uhlobo oluku-inthanethi lweGastroenterology Septhemba 15, 2017).
Lokhu kufanele kube yisifundo sokuqala esizinze ezweni lonke ukuhlola ubudlelwano phakathi kokugoma nekholera ngemuva kokutholakala komdlavuza obomvu kanye nengozi yokufa. Ucwaningo lwangaphambilini lukhombisile ukuthi umuthi wokugomela ikholera ungaba nemithelela eminingi ekulawuleni amasosha omzimba futhi unganciphisa nokwakheka kwama-colon polyp kumamodeli wegundane.
The researchers believe that umdlavuza colorectal is more common in developed countries than in developing countries. Perhaps less exposure to microbes in childhood is also associated with an increased risk of developing colorectal cancer in adulthood.
The researchers used the Swedish National Cancer Registration and Prescription Drug Registration Database to retrospectively analyze the data of 175 patients who received cholera vaccine after diagnosis of colorectal cancer from mid-2005 to 2012. As for the reason why the cholera vaccine is unknown, it may be that patients need to travel to other countries.
Ukuhlaziywa kubonise ukuthi uma kuqhathaniswa neziguli ezingazange zigonywe ikholera (iziguli ezingama-525), iziguli ezathola umuthi wokugomela ikholera ngemuva kokutholakala komdlavuza onamabala zinengcuphe ephansi engama-47% yokufa komdlavuza obomvu kanye ne-41% engcupheni yokufa. Le nzuzo yokusinda ikhona ezigulini ezineminyaka ehlukene, ubulili, nezigaba zomdlavuza obala kakhulu lapho kutholakala ukuxilongwa.
Abaphenyi bacabanga ukuthi umuthi wokugomela ikholera ungadlala indima ekuvimbeleni ukuqhubeka komdlavuza obala ngokuvuselela amaseli omzimba afana namaseli ama-CD8 ama-T, ama-macrophage namaseli we-NK, kanye / noma ngokuthinta ukubonakaliswa kwezakhi zofuzo ezihlobene ne-tumorigenesis. Abaphenyi bakholelwa ukuthi uma imiphumela yalezi zifundo ingaqinisekiswa kwezinye izifundo ezenzelwe abantu noma izifundo zomtholampilo ezingahleliwe, ukusetshenziswa komuthi wokugomela ikholera ekwelapheni i-adjuvant ukwelashwa komdlavuza wobala akunakwenzeka.
Abaphenyi abacwaninga ngokutheleleka ngamagciwane nezimila baveze ukuthi ubufakazi obuningi kakhulu bocwaningo buyasekela ukuthi amagciwane noma imikhiqizo yabo ingavuselela amasosha omzimba futhi ilethe izinzuzo zezempilo ekuvikeleni izinhlobo ezithile zamathumba nezifo ezihlobene nokuzivikela komzimba. izimo zisenza sinciphe amathuba okuthola amasosha omzimba aphilile abangelwa ukuvezwa kwamagciwane. Umuthi wokugoma ngomlomo ophephile ongaqinisa ukusebenza komzimba ungasilethela izinzuzo ezinkulu zezempilo.
