Ocwaningweni lwangaphambilini, abacwaningi baye bacacisa ukuthi ukuthatha i-aspirin kungasiza kanjani ukuvimbela umdlavuza wamathumbu. Lolu cwaningo luthole ukuthi ama-analgesics avimba izinqubo ezibalulekile ezihlobene nokwakheka kwesimila. Njengoba sonke sazi, i-aspirin evamile inganciphisa ingozi yomdlavuza wekoloni, kodwa izakhiwo ze-anti-tumor zalo muthi aziqondwa ngokugcwele.
Researchers at the University of Edinburgh are concerned with a structure called nucleolus found in cells. The activation of nucleoli causes isisu formation, and dysfunction is also associated with Alzheimer’s disease and Parkinson’s disease. A team from the University of Edinburgh Cancer Research Centre in the United Kingdom tested the effect of aspirin on laboratory-grown cells and tumor biopsies in patients with colon cancer.
Bathole ukuthi i-aspirin ingavimba i-molecule eyisihluthulelo ebizwa nge-TIF-IA, eyi-molecule eyisihluthulelo somsebenzi we-nucleolus.
Akuzona zonke iziguli ezinomdlavuza wekoloni eziphendula i-aspirin, kepha abacwaningi bathi okutholakele kwabo kungasiza ekunqumeni ukuthi iziphi okungenzeka zizuze.
I-Aspirin inemiphumela engemihle, kufaka phakathi ukuphuma kwegazi kwangaphakathi, okungadala izinhlobo ezithile zesifo sohlangothi futhi akunconywa ukusetshenziswa kwesikhathi eside. Abaphenyi bathi lolu cwaningo luvula indlela yokwakhiwa kwemithi yokwelashwa emisha nephephile elingisa imiphumela ye-aspirin. Ucwaningo lushicilelwe ephephabhukwini iNucleic Acid Research futhi lwaxhaswa nguMkhandlu Wezocwaningo Lwezokwelapha, iBiotechnology neBiological Sciences Research Council. Ucwaningo lomdlavuza emhlabeni wonke, ucwaningo lwamathumbu nomdlavuza, kanye neRose Tree Trust nawo uyawusekela lo msebenzi.
Abaphenyi eCancer Cancer Center e-Edinburgh, e-UK, bathe: “Sijabule kakhulu ngalokhu okutholakele ngoba baphakamise indlela ye-aspirin yokuvimbela izifo eziningi. Ngokuqonda kangcono ukuthi i-aspirin iyivimba kanjani i-TIF-IA nomsebenzi we-nucleolar, Inikeza ithemba elikhulu ngokuthuthukiswa kwezindlela zokwelapha ezintsha kanye nokwakhiwa kwemithi ehlosiwe. ”
