Deyarli barcha bachadon bo'yni saratoni jinsiy yo'l bilan yuqadigan infektsiyalarning "umumiy sovuqligi" deb ataladigan inson papillomavirusi (HPV) tufayli yuzaga keladi, chunki faol hayot xarakteriga ega deyarli har bir kishi u bilan kasallanadi. Yaxshiyamki, immunitet tizimi inson papillomavirusi infektsiyalarining ko'pini mag'lub qiladi va odamlarning faqat kichik bir qismi saratondan oldingi bosqichga o'tadi va oxir-oqibat saratonga aylanadi. Ammo nega ba'zi odamlar infektsiyani yo'q qilishlari mumkin, agar boshqalar unga qarshi tura olmasa?
To answer this question, Dr. Melissa M.Herbst-Kralovetz of the University of Arizona Cancer Center, an associate professor at the Phoenix Medical School at Union University, studied 100 premenopausal women and found a link between vaginal bacteria and cervical cancer. Compared with cervical cancer and precancerous patients, women with no cervical abnormalities have different vaginal bacterial communities. This difference reveals the direct relationship between “good” bacteria and cervical health. “Bad” bacteria increase the risk of cancer.
Bu yerdagi mikroblar hamjamiyati inson tanasida parazitlik qiluvchi bakteriyalar birlashmasi. Masalan, sut kislotasi bakteriyalari yogurtdagi probiotiklar bilan bog'liq, ammo yogurtdagi probiotiklardan farqli o'laroq, bu erda uchraydigan ba'zi bakteriyalar qin muhitining sog'lig'iga yordam berishi mumkin. Masalan, avvalgi tadqiqotlar shuni ko'rsatdiki, qin mikroblari bo'lgan ayollar asosan gazsimon Laktobatsillus HPV infektsiyasini tez-tez tozalaydi. Yaxshi bakteriyalar ham o'z hududlarini saqlab, yomon bakteriyalar kirib kelishining oldini oladi. Biroq, ba'zan ular bu yer uchun kurashda yutqazishadi.
Bachadon bo'yni saratoni va prekanseröz bemorlarda sut kislotasi bakteriyalari - foydali bakteriyalar zararli bakteriyalar aralashmasi bilan almashtiriladi. Tadqiqotda sut kislotasi bakteriyalari kamayganligi sababli bachadon bo'yni anormalliklari jiddiylashdi. Boshqa tomondan, Sneathia deb nomlangan zararli bakteriyalar saratondan oldin, HPV infektsiyasi va bachadon bo'yni saratoni bilan bog'liq.
Sneathia are rod-shaped bacteria that can grow into fiber chains. They are related to other gynecological diseases, including bacterial vaginosis, miscarriage, premature delivery, HPV infection and cervical cancer. Dr. Herbst-Kralovetz ’s research found for the first time that a large number of Sneathia populations are associated with all stages of the HPV-to-cancer continuum, from the initial HPV infection to precancerous lesions to invasive cervical cancer.
Sneathia HPV infektsiyalari yoki saraton kasalligining shakllanishiga faol yordam beradimi yoki ular shunchaki o'yin-kulgi uchunmi, aniq emas. Hozirgi tadqiqot faqat vaqt o'tishi bilan ayollarning suratlarini taqdim etadi. Nedensellikni aniqlash uchun kelajakdagi tadqiqotlar vaqt o'tishi bilan amalga oshirilishi kerak.
